January 13, 2015 Issue of JAMA

January 13, 2015, Vol 313, No. 2, Pages 111-212 | Scientific Discovery and the Future of Medicine

This Week in JAMA

Highlights

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JAMA. 2015;313(2):111-113. doi:10.1001/jama.2014.11511

Podcast: New JAMA series: Scientific Discovery and the Future of Medicine, CVD prevention and outcomes in a rural setting, asthma and OSA, and more.

Original Investigation

Community-Wide Cardiovascular Disease Prevention Programs and Health Outcomes in a Rural County, 1970-2010

N. Burgess Record, MD; Daniel K. Onion, MD, MPH; Roderick E. Prior, MD; et al.

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JAMA. 2015;313(2):147-155. doi:10.1001/jama.2014.16969

This 40-year observational study reports that sustained, community-wide programs targeting cardiovascular risk factors and behavior changes to improve a Maine county鈥檚 population health were associated with reductions in hospitalization and mortality.

Editorial
Improving Cardiovascular Health in a Rural Population: Can Other Communities Do the Same?
Darwin R. Labarthe, MD, MPH, PhD; Jeremiah Stamler, MD

JAMA

Association Between Asthma and Risk of Developing Obstructive Sleep Apnea

Mihaela Teodorescu, MD, MS; Jodi H. Barnet, MS; Erika W. Hagen, PhD; et al.

Abstract Full Text

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JAMA. 2015;313(2):156-164. doi:10.1001/jama.2014.17822

Dr Teodorescu and coauthors examine the prospective relationship of asthma with incident obstructive sleep apnea (OSA) among 547 adults in Wisconsin.

Differences in Breast Cancer Stage at Diagnosis and Cancer-Specific Survival by Race and Ethnicity in the United States

Javaid Iqbal, MD; Ophira Ginsburg, MD, FRCPC; Paula A. Rochon, MD, MPH, FRCPC; et al.

Abstract Full Text

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JAMA. 2015;313(2):165-173. doi:10.1001/jama.2014.17322

This observational database study using the Surveillance, Epidemiology, and End Results 18 registries reports that among US women diagnosed with invasive breast cancer, the likelihood of diagnosis at an early stage, and survival after stage I diagnosis, varied by race and ethnicity.

Podcast: Breast Cancer Stage at Diagnosis and Survival

Editorial
Race, Ethnicity, and the Diagnosis of Breast Cancer
Bobby Daly, MD, MBA; Olufunmilayo I. Olopade, MBBS, FACP

JAMA

Research Letter

Variation in and Factors Associated With Use of Episiotomy

Alexander M. Friedman, MD; Cande V. Ananth, PhD, MPH; Eri Prendergast, MS; et al.

Abstract Full Text

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JAMA. 2015;313(2):197-199. doi:10.1001/jama.2014.14774

Special Communication

Scientific Discovery and the Future of Medicine

The Anatomy of Medical Research: US and International Comparisons

Hamilton Moses III, MD; David H. M. Matheson, JD, MBA; Sarah Cairns-Smith, PhD; et al.

Abstract Full Text

JAMA. 2015;313(2):174-189. doi:10.1001/jama.2014.15939

This Special Communication compares investment in medical research in the United States and other developed countries over the past 2 decades by quantifying total public and private investment and personnel and evaluating resulting patents, publications, drug and device approvals, and value created.

Editorial
Restore the US Lead in Biomedical Research
Victor J. Dzau, MD; Harvey V. Fineberg, MD, PhD

JAMA
Scientific Discovery and the Future of Medicine
Phil B. Fontanarosa, MD, MBA; Howard Bauchner, MD

JAMA

Viewpoint

Scientific Discovery and the Future of Medicine

Exceptional Opportunities in Medical Science: A View From the National Institutes of Health

Francis S. Collins, MD, PhD

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JAMA. 2015;313(2):131-132. doi:10.1001/jama.2014.16736

This viewpoints reviews the health breakthroughs brought by the National Institutes of Health, considers new opportunities in research, and calls for adequate funding to ensure those promises are fulfilled.

Editorial
Scientific Discovery and the Future of Medicine
Phil B. Fontanarosa, MD, MBA; Howard Bauchner, MD

JAMA

Scientific Discovery and the Future of Medicine

Supporting Biomedical Research: Meeting Challenges and Opportunities at HHMI

Robert Tjian, PhD

Abstract Full Text

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JAMA. 2015;313(2):133-135. doi:10.1001/jama.2014.16543

This Viewpoint discusses how the Howard Hughes Medical Institute is responding the challenges and opportunities related to the training of patient-oriented physician-scientists.

Editorial
Scientific Discovery and the Future of Medicine
Phil B. Fontanarosa, MD, MBA; Howard Bauchner, MD

JAMA

Scientific Discovery and the Future of Medicine

Nanotechnology

Robert Langer, ScD; Ralph Weissleder, MD, PhD

Abstract Full Text

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JAMA. 2015;313(2):135-136. doi:10.1001/jama.2014.16315

This Viewpoint explores nanotechnology for therapeutics, diagnostics, and imaging.

Podcast: Nanotechnology

Editorial
Scientific Discovery and the Future of Medicine
Phil B. Fontanarosa, MD, MBA; Howard Bauchner, MD

JAMA

A Piece of My Mind

Take a Look at Me Now

Quinn Leslie, MD

Abstract Full Text

JAMA. 2015;313(2):137-138. doi:10.1001/jama.2014.15774

Editorial

Improving Cardiovascular Health in a Rural Population: Can Other Communities Do the Same?

Darwin R. Labarthe, MD, MPH, PhD; Jeremiah Stamler, MD

Abstract Full Text

JAMA. 2015;313(2):139-140. doi:10.1001/jama.2014.16963

Race, Ethnicity, and the Diagnosis of Breast Cancer

Bobby Daly, MD, MBA; Olufunmilayo I. Olopade, MBBS, FACP

Abstract Full Text

JAMA. 2015;313(2):141-142. doi:10.1001/jama.2014.17323

Scientific Discovery and the Future of Medicine

Restore the US Lead in Biomedical Research

Victor J. Dzau, MD; Harvey V. Fineberg, MD, PhD

Abstract Full Text

JAMA. 2015;313(2):143-144. doi:10.1001/jama.2014.17660

Editorial
Scientific Discovery and the Future of Medicine
Phil B. Fontanarosa, MD, MBA; Howard Bauchner, MD

JAMA

Scientific Discovery and the Future of Medicine

Phil B. Fontanarosa, MD, MBA; Howard Bauchner, MD

Abstract Full Text

JAMA. 2015;313(2):145-146. doi:10.1001/jama.2014.17937

Editorial
Restore the US Lead in Biomedical Research
Victor J. Dzau, MD; Harvey V. Fineberg, MD, PhD

JAMA

From the 糖心vlog

Rates of Psychiatrists鈥� Participation in Health Insurance Networks

Janet R. Cummings, PhD

Abstract Full Text

JAMA. 2015;313(2):190-191. doi:10.1001/jama.2014.12472

JAMA Clinical Guidelines Synopsis

Screening for Asymptomatic Carotid Artery Stenosis

George W. Weyer, MD; Andrew M. Davis, MD, MPH

Abstract Full Text

JAMA. 2015;313(2):192-194. doi:10.1001/jama.2014.16804

This JAMA Clinical Guidelines Synopsis article evaluates the most recent US Preventive Services Task Force guideline on screening for carotid artery stenosis in asymptomatic adults.

JAMA Diagnostic Test Interpretation