Ingrid M. Libman, MD, PhD; Kellee M. Miller, PhD; Linda A. DiMeglio, MD, MPH; et al.
free access
has audio
JAMA. 2015;314(21):2241-2250. doi:10.1001/jama.2015.16174
This randomized trial reports that the addition of metformin to insulin does not improve glycemic control in overweight adolescents with type 1 diabetes and increases incidence of gastrointestinal adverse events.
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Podcast:
Metformin for Adolescents With Type 1 Diabetes
Mihai Gheorghiade, MD; Stephen J. Greene, MD; Javed Butler, MD, MPH, MBA; et al.
free access
JAMA. 2015;314(21):2251-2262. doi:10.1001/jama.2015.15734
This phase 2 study investigates the optimal dose and tolerability of vericiguat, a soluble guanylate cyclase stimulator, in patients with worsening chronic heart failure with reduced left ventricular ejection fraction.
George Molina, MD, MPH; Thomas G. Weiser, MD, MPH; Stuart R. Lipsitz, ScD; et al.
free access
has multimedia
has audio
JAMA. 2015;314(21):2263-2270. doi:10.1001/jama.2015.15553
This ecological study uses World Bank World Development database data to investigate associations between national cesarean delivery rates and maternal and neonatal mortality rates in 194 World Health Organization member countries in 2012.
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Podcast:
Cesarean Delivery Rate and Maternal and Neonatal Mortality
Mairead Black, MRCOG; Siladitya Bhattacharya, MD; Sam Philip, MD; et al.
free access
JAMA. 2015;314(21):2271-2279. doi:10.1001/jama.2015.16176
This population epidemiology study uses national health databases in Scotland to investigate associations between planned cesarean delivery in a first pregnancy and childhood asthma requiring hospital admission between 1993 and 2015.
Daniel J. Bratton, PhD; Thomas Gaisl, MD; Annette M. Wons, MD; et al.
free access
JAMA. 2015;314(21):2280-2293. doi:10.1001/jama.2015.16303
This meta-analysis of trials comparing treatments for obstructive sleep apnea investigates associations between continuous positive airway pressure vs mandibular advancement devices and change in blood pressure.