糖心vlog

This phase 2 randomized clinical trial evaluates the optimal dose, dosing interval, and safety of zerlasiran, a small-interfering RNA targeting hepatic synthesis of apolipoprotein(a), to treat patients with atherosclerotic cardiovascular disease and elevated lipoprotein(a) concentration.

This randomized clinical trial assesses the effect of muvalaplin on lipoprotein(a) concentrations in patients with high baseline lipoprotein(a) levels and cardiovascular risk factors.

This clinical trial evaluates whether linear ablation combined with ethanol infusion of the vein of Marshall and pulmonary vein isolation (PVI) is more effective than PVI alone in patients with persistent atrial fibrillation.

This study compares differences in caregiver-reported hospice quality across categories of ownership, including for-profit private equity firm (PEF)/publicly traded company (PTC)鈥搊wned and non-PEF/PTC鈥搊wned hospices as well as not-for-profit鈥搊wned hospices.

This Viewpoint summarizes how the US Preventive Services Task Force specifies target populations for its recommendations and highlights 3 problems鈥攊ncluding exacerbation of health inequities鈥攑osed by the proposed use of more complex risk models to better identify target populations and increase effectiveness and efficiency of prevention efforts (鈥減recision prevention鈥�).

This narrative review investigates the diagnosis, symptoms, and management of polycythemia vera and explores the efficacy of treatments like low-dose aspirin, therapeutic phlebotomy, and cytoreductive therapies.

This JAMA Insights explores how clinicians can use the harm reduction communication framework to engage with patients who have opioid use disorder, which could help prevent overdose and other substance use鈥搑elated harms.

This JAMA Insights explores harm reduction strategies for people who use drugs and the clinicians who treat them to help reduce the risk of unintentional drug overdose and infection.

This study aims to characterize the individual-level agreement of polygenic risk scores for coronary heart disease that perform similarly at the population level.

While watching the 2024 election night results and considering possible health care policies, a pediatrician reflects on his role in engaging in conversations about politics and policy as an advocate for patients.

This Medical News article is an interview with Sarah C. Hull, MD, MBE, a cardiologist and clinical ethicist at Yale School of Medicine, about appropriate boundaries for use of artificial intelligence in clinical settings.

This Medical News article discusses a popular bystander training program for on-the-job mental health crises.

This Medical News article discusses new research on how HPV infection in men may affect sperm.

This noninferiority randomized clinical trial investigates whether administering tenofovir to pregnant individuals with hepatitis B virus beginning at gestational week 16 is noninferior to administering tenofovir beginning at gestational week 28 in preventing mother-to-child transmission.

This study investigates trends in hospitalization and liver transplant rates in the US from 2005 to 2021 associated with alcohol-induced liver disease.

This study assesses artemisinin partial resistance, Pfkelch13 variations, and malaria recrudescence in Ugandan children with complicated malaria.

This Viewpoint discusses a sector-wide approach to hepatitis C virus elimination, including not only jails and prisons, but also community supervision and alternatives to incarceration programs.

This Viewpoint highlights 10 categories of recommendations for preparing for current and future hurricane seasons.

In this narrative medicine essay, a family planning fellow discusses how undergoing an abortion, the procedure she specializes in performing, has deepened her perception of the concept of the difficult components of choice and helped her understand the difference in providing vs experiencing care.

This JAMA Clinical Guidelines Synopsis summarizes the 2023 ACC/AHA/ACCP/HRS guideline for the diagnosis and management of atrial fibrillation.

This JAMA Patient Page describes knee osteoarthritis and its symptoms, diagnosis, and treatments.

This randomized cluster trial examines whether thrice-weekly symptom screening with symptom feedback and management care pathways, compared with usual care, improves overall self-reported symptoms in pediatric patients with cancer.

This study evaluates representation of older adults, women, and people of Black race and Hispanic ethnicity in Centers for Medicare & Medicaid Services national coverage determination (NCD) and coverage with evidence development (CED)鈥揳pproved studies.

This Viewpoint discusses the health benefits of glucagon-like peptide-1 receptor agonists (GLP-1 RAs); summarizes the clinical, policy, and equity implications of GLP-1 RA discontinuation; and calls for the identification and implementation of strategies to improve long-term adherence to GLP-1 RA therapy.

This randomized trial assesses the effect of intratracheal budesonide mixed with surfactant on survival free of bronchopulmonary dysplasia in extremely preterm infants.

This study assesses whether online vaping retailers adhere to age verification, shipping method, and flavor restrictions in California.

This Viewpoint discusses enrollment in Medicare Advantage vs traditional Medicare among older adults and common reasons for plan disenrollment, including the lack of in-network physicians and hospitals.

This narrative review explores treatment with surgical aortic valve replacement vs transcatheter aortic valve implantation in older adults with severe symptomatic calcific aortic stenosis, including the type and timing of valve replacement.

This Medical News article is an interview with National Academy of Sciences President Marcia McNutt, PhD, and JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, about responsible use of generative AI for scientific research.

This Medical News article discusses the first high-level meeting on antimicrobial resistance at the United Nations since 2016 and a new report on the global burden of bacterial antimicrobial resistance.

This study analyzes the extent and persistence of payments to physicians from competing manufacturers after receipt of payment from manufacturers of first-in-class products entering 6 novel therapeutic classes.

In this narrative medicine essay, a medical student discusses the challenges of conveying her grandmother鈥檚 feelings to her physician while serving as an interpreter for her grandparents鈥� clinic visits.

This JAMA Insights discusses the important role that interpreters play in facilitating communication between patients with limited English-language proficiency and their health care team and provides steps that can be taken to improve communication with remote interpreters for patients.

This JAMA Patient Page describes the types of chronic pruritus and its symptoms and signs and treatment strategies.

This prespecified, retrospective observational cohort study examines the trends in inferior vena cava filter insertion and retrieval for the prevention of venous thromboembolism among US Medicare beneficiaries.

This Viewpoint investigates the lack of a comprehensive infectious diseases alert system in the US and proposes solutions for such a system, including linking changing threat levels to specific response actions.

A 30-year-old nulliparous woman with obesity and history of migraines and depression had 1 month of daily headaches, transient bilateral visual blurring, persistent vision loss in the temporal region of one eye, pulsatile tinnitus, and mild bilateral papilledema. What is the diagnosis and what would you do next?

This study examines the relationship between pharmacy closures and anticonvulsant prescription fills and number of days supplied.

This Viewpoint discusses the implications that the 2024 presidential election may have on the status of the temporary expansions to the Affordable Care Act鈥檚 Advanced Premium Tax Credits.

This Viewpoint discusses ways for health systems, professional societies, and academic physicians to develop and share effective teaching materials and strategies with community-based colleagues.

This review summarizes evidence regarding cellular immunotherapies for cancer.

This randomized clinical trial compares the effect on child weight-for-length trajectory of adding a digital childhood obesity prevention intervention to health behavior counseling delivered by pediatric primary care clinicians.

This Medical News article discusses the impact of the Texas abortion ban on obstetrician-gynecologists and their patients in the state and beyond.