June 2, 2015 Issue of JAMA

June 2, 2015, Vol 313, No. 21, Pages 2099-2196

This Week in JAMA

Highlights

Abstract Full Text

free access has audio

JAMA. 2015;313(21):2099-2101. doi:10.1001/jama.2014.11777

Podcast: Preventing acute kidney injury with remote ischemic preconditioning, maternal antidepressant use and newborn pulmonary hypertension, a comparison of ACO and fee-for-service healthcare delivery models, and more.

Original Investigation

Caring for the Critically Ill Patient

Effect of Remote Ischemic Preconditioning on Kidney Injury Among High-Risk Patients Undergoing Cardiac Surgery: A Randomized Clinical Trial

Alexander Zarbock, MD; Christoph Schmidt, MD; Hugo Van Aken, MD; et al.

Abstract Full Text

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JAMA. 2015;313(21):2133-2141. doi:10.1001/jama.2015.4189

This randomized trial reports that in high-risk patients undergoing cardiac surgery, remote ischemic preconditioning performed via blood pressure cuff inflation significantly reduced the rate of acute kidney injury and renal replacement therapy.

Editorial
Remote Ischemic Preconditioning for Kidney Protection
Jenny Szu-Chin Pan, MD; David Sheikh-Hamad, MD

JAMA

Antidepressant Use Late in Pregnancy and Risk of Persistent Pulmonary Hypertension of the Newborn

Krista F. Huybrechts, MS, PhD; Brian T. Bateman, MD, MSc; Kristin Palmsten, ScD; et al.

Abstract Full Text

free access has multimedia has audio

JAMA. 2015;313(21):2142-2151. doi:10.1001/jama.2015.5605

An analysis of more than 3.7 million pregnant women enrolled from 2000 through 2010 in Medicaid found an association between use of selective serotonin reuptake inhibitors and newborns with persistent pulmonary hypertension.

Podcast: Antidepressant Use Late in Pregnancy and Effects on Newborn

Association of Pioneer Accountable Care Organizations vs Traditional Medicare Fee for Service With Spending, Utilization, and Patient Experience

David J. Nyweide, PhD; Woolton Lee, PhD; Timothy T. Cuerdon, PhD; et al.

Abstract Full Text

free access has audio

JAMA. 2015;313(21):2152-2161. doi:10.1001/jama.2015.4930

This population epidemiology study uses administrative data to compare differences in spending, utilization, and patient experiences associated with an accountable care organization vs traditional fee for service among Medicare beneficiaries.

Podcast: Outcomes for ACOs vs Traditional Medicare Fee for Service

Editorial
Pioneer Accountable Care Organizations: Traversing Rough Country
Lawrence P. Casalino, MD, PhD

JAMA
Accountable Care Organizations and Evidence-Based Payment Reform
Mark McClellan, MD, PhD

JAMA

Association of a Bundled Intervention With Surgical Site Infections Among Patients Undergoing Cardiac, Hip, or Knee Surgery

Marin L. Schweizer, PhD; Hsiu-Yin Chiang, MS, PhD; Edward Septimus, MD; et al.

Abstract Full Text

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JAMA. 2015;313(21):2162-2171. doi:10.1001/jama.2015.5387

Schweizer and coauthors evaluate whether the implementation of an evidence-based bundle is associated with a lower risk of Staphylococcus aureus surgical site infections in patients undergoing cardiac operations or hip or knee arthroplasties.

Editorial
Bundled Approaches for Surgical Site Infection Prevention: The Continuing Quest to Get to Zero
Preeti N. Malani, MD, MSJ

JAMA

Research Letter

Appropriateness of Advanced Diagnostic Imaging Ordering Before and After Implementation of Clinical Decision Support Systems

Peter S. Hussey, PhD; Justin W. Timbie, PhD; Lane F. Burgette, PhD; et al.

Abstract Full Text

free access

JAMA. 2015;313(21):2181-2182. doi:10.1001/jama.2015.5089

This observational study uses computerized radiology order entry and clinical decision support systems to examine the proportion and appropriateness of those orders placed by participating clinicians in 8 states between the baseline and intervention periods.

Viewpoint

A Public Health Perspective on a National Precision Medicine Cohort: Balancing Long-term Knowledge Generation With Early Health Benefit

Muin J. Khoury, MD, PhD; James P. Evans, MD, PhD

Abstract Full Text

JAMA. 2015;313(21):2117-2118. doi:10.1001/jama.2015.3382

This Viewpoint discusses the potential public health benefits of using genomic information in a large population-based cohort.

The Precision Medicine Initiative: A New National Effort

Euan A. Ashley, MRCP, DPhil

Abstract Full Text

JAMA. 2015;313(21):2119-2120. doi:10.1001/jama.2015.3595

This Viewpoint discusses the distinction between personalized and precision medicine and the roles the US initiative can play in addressing unmet needs and remaining challenges.

Cognitive Aging: A Report From the Institute of Medicine

Dan G. Blazer, MD, MPH, PhD; Kristine Yaffe, MD; Jason Karlawish, MD

Abstract Full Text

has audio

JAMA. 2015;313(21):2121-2122. doi:10.1001/jama.2015.4380

This Viewpoint summarizes recommendations made by the Institute of Medicine in its April 2015 report on the clinical and public health dimensions of cognitive aging.

Podcast: IOM Report on Cognitive Aging

A Piece of My Mind

Penny Wise

Michael Melgar, MD

Abstract Full Text

JAMA. 2015;313(21):2123. doi:10.1001/jama.2015.5487

Editorial

Remote Ischemic Preconditioning for Kidney Protection

Jenny Szu-Chin Pan, MD; David Sheikh-Hamad, MD

Abstract Full Text

JAMA. 2015;313(21):2124-2125. doi:10.1001/jama.2015.5085

Pioneer Accountable Care Organizations: Traversing Rough Country

Lawrence P. Casalino, MD, PhD

Abstract Full Text

JAMA. 2015;313(21):2126-2127. doi:10.1001/jama.2015.5086

Accountable Care Organizations and Evidence-Based Payment Reform

Mark McClellan, MD, PhD

Abstract Full Text

JAMA. 2015;313(21):2128-2130. doi:10.1001/jama.2015.5087

Bundled Approaches for Surgical Site Infection Prevention: The Continuing Quest to Get to Zero

Preeti N. Malani, MD, MSJ

Abstract Full Text

JAMA. 2015;313(21):2131-2132. doi:10.1001/jama.2015.6018

From the 糖心vlog

Increasing Support for the Treatment of Complicated Grief in Adults of All Ages

Naomi M. Simon, MD, MSc

Abstract Full Text

JAMA. 2015;313(21):2172-2173. doi:10.1001/jama.2015.105

JAMA Clinical Challenge

Enlarged Thymus in a Patient With Dyspnea and Weight Loss

Wenyu Huang, MD, PhD; Mark E. Molitch, MD

Abstract Full Text

JAMA. 2015;313(21):2174-2175. doi:10.1001/jama.2015.2713

A 36-year-old woman reporting 1 month of dyspnea presents with weight loss, tongue and hand tremors, and tachycardia. What would you do next?

From The Medical Letter on Drugs and Therapeutics

An Inhaled Insulin (Afrezza)

Abstract Full Text

JAMA. 2015;313(21):2176-2177. doi:10.1001/jama.2015.5634

This Medical Letter drug review summarizes a newly approved inhaled, rapid-acting formulation of recombinant human insulin for treatment of adults with type 1 or type 2 diabetes.

Medical News & Perspectives

Improving the Quality of Life at the End of Life

Rita Rubin, MA

Abstract Full Text

JAMA. 2015;313(21):2110-2112. doi:10.1001/jama.2015.4234

This Medical News & Perspectives article discusses the challenges of end-of-life care and how innovations in health care delivery can change the decision-making and care process.

News From the Food and Drug Administration