April 7, 2015 Issue of JAMA

糖心vlog

April 7, 2015, Vol 313, No. 13, Pages 1291-1386

This Week in JAMA

Highlights

Abstract Full Text

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JAMA. 2015;313(13):1291-1293. doi:10.1001/jama.2014.11665

Podcast: Folate for stroke prevention, bivalirudin during PCI for myocardial infarction, cancer risk by BRCA type and location, and more.

Original Investigation

Efficacy of Folic Acid Therapy in Primary Prevention of Stroke Among Adults With Hypertension in China: The CSPPT Randomized Clinical Trial

Yong Huo, MD; Jianping Li, MD, PhD; Xianhui Qin, PhD; et al.

Abstract Full Text

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JAMA. 2015;313(13):1325-1335. doi:10.1001/jama.2015.2274

This randomized, double-blind clinical trial found that among adults with hypertension in China without a history of stroke or myocardial infarction, the combined use of enalapril and folic acid, compared with enalapril alone, significantly reduced the risk of first stroke.

Video: Efficacy of Folic Acid Therapy in Primary Prevention of Stroke Among Adults With Hypertension in China: The CSPPT Randomized Clinical Trial

Podcast: Folic Acid for Stroke Prevention in Hypertension

Editorial
Folate Supplements for Stroke Prevention: Targeted Trial Trumps the Rest
Meir Stampfer, MD, DrPH; Walter Willett, MD, DrPH

JAMA

Bivalirudin vs Heparin With or Without Tirofiban During Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction: The BRIGHT Randomized Clinical Trial

Yaling Han, MD, PhD; Jincheng Guo, MD; Yang Zheng, MD; et al.

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JAMA. 2015;313(13):1336-1346. doi:10.1001/jama.2015.2323

This randomized superiority trial in China found that among patients undergoing PCI, bivalirudin was associated with reduced adverse effects compared with heparin alone and heparin plus tirofiban.

Editorial
Can BRIGHT Restore the Glow of Bivalirudin?
Matthew A. Cavender, MD, MPH; David P. Faxon, MD

JAMA

Association of Type and Location of BRCA1 and BRCA2 Mutations With Risk of Breast and Ovarian Cancer

Timothy R. Rebbeck, PhD; Nandita Mitra, PhD; Fei Wan, MS; et al.

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JAMA. 2015;313(13):1347-1361. doi:10.1001/jama.2014.5985

This genetic epidemiology study reports that risk of breast and ovarian cancer among women with BRCA1 and BRCA2 mutations varies by mutation type and location.

Research Letter

Patients With Next-of-Kin Relationships Outside the Nuclear Family

Andrew B. Cohen, MD, DPhil; Mark Trentalange, MD, MPH; Terri Fried, MD

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JAMA. 2015;313(13):1369-1370. doi:10.1001/jama.2015.2409

Viewpoint

Vitamin D Research and Clinical Practice: At a Crossroads

JoAnn E. Manson, MD, DrPH; Shari S. Bassuk, ScD

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JAMA. 2015;313(13):1311-1312. doi:10.1001/jama.2015.1353

This Viewpoint discusses vitamin D screening and supplemental vitamin D for nonskeletal health benefits in light of existing recommendations and large-scale trials in progress.

Podcast: Vitamin D Research and Clinical Practice

Hospital Credentialing and Privileging of Surgeons: A Potential Safety Blind Spot

Jason C. Pradarelli, BS; Darrell A. Campbell Jr, MD; Justin B. Dimick, MD, MPH

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JAMA. 2015;313(13):1313-1314. doi:10.1001/jama.2015.1943

This Viewpoint reviews an important legal ruling on robotic surgery that highlights potential safety concerns in hospital credentialing and privileging with regard to new technologies.

Podcast: Hospital Credentialing and Privileging of Surgeons

The Rise of the Medical Scribe Industry: Implications for the Advancement of Electronic Health Records

George A. Gellert, MD, MPH, MPA; Ricardo Ramirez, LVN; S. Luke Webster, MD

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JAMA. 2015;313(13):1315-1316. doi:10.1001/jama.2014.17128

This Viewpoint argues that the increasing use of medical scribers to record patient data will impede the development of electronic health record management systems.

State Innovation Model Initiative: A State-Led Approach to Accelerating Health Care System Transformation

Lauren S. Hughes, MD, MPH; Alon Peltz, MD, MBA; Patrick H. Conway, MD, MSc

Abstract Full Text

JAMA. 2015;313(13):1317-1318. doi:10.1001/jama.2015.2017

This Viewpoint describes the State Innovation Model initiative, including innovations states have made for health care delivery systems as well as lessons learned.

A Piece of My Mind

The Other Generation

Shlok Gupta, MD; Susanna Mak, MD, PhD; Allan S. Detsky, MD, PhD

Abstract Full Text

JAMA. 2015;313(13):1319-1320. doi:10.1001/jama.2015.1082

Editorial

Folate Supplements for Stroke Prevention: Targeted Trial Trumps the Rest

Meir Stampfer, MD, DrPH; Walter Willett, MD, DrPH

Abstract Full Text

JAMA. 2015;313(13):1321-1322. doi:10.1001/jama.2015.1961

Can BRIGHT Restore the Glow of Bivalirudin?

Matthew A. Cavender, MD, MPH; David P. Faxon, MD

Abstract Full Text

JAMA. 2015;313(13):1323-1324. doi:10.1001/jama.2015.2345

From the 糖心vlog

Multiple Blood Pressure Medications and Mortality Among Elderly Individuals

Wilbert S. Aronow, MD

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JAMA. 2015;313(13):1362-1363. doi:10.1001/jama.2015.248

JAMA Clinical Evidence Synopsis

Association Between Perioperative Low-Molecular-Weight Heparin vs Unfractionated Heparin and Clinical Outcomes in Patients With Cancer Undergoing Surgery

Elie A. Akl, MD, MPH, PhD; Lara A. Kahale, BSN; Holger J. Schünemann, MD, PhD, MSc

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JAMA. 2015;313(13):1364-1365. doi:10.1001/jama.2015.498

JAMA Clinical Challenge

Painful Rash in a Patient With Bronchiectasis

Sruthi Renati, BS; Adam Raff, MD, PhD; Susan Burgin, MD

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JAMA. 2015;313(13):1366-1367. doi:10.1001/jama.2015.0985

Medical News & Perspectives

Exome Sequencing Comes to the Clinic

Ricki Lewis, PhD

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JAMA. 2015;313(13):1301-1303. doi:10.1001/jama.2015.1389

News From the Food and Drug Administration

Testosterone Medications Need New Label Information

Rita Rubin, MA

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JAMA. 2015;313(13):1306. doi:10.1001/jama.2015.2192

New Antibacterial Drug Approved

Rita Rubin, MA

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JAMA. 2015;313(13):1306. doi:10.1001/jama.2015.2800

Diabetes: 1 Pen, 1 Patient

Rita Rubin, MA

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JAMA. 2015;313(13):1306. doi:10.1001/jama.2015.2802

FDA Okays First Direct-to-Consumer Genetic Test

Rita Rubin, MA

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JAMA. 2015;313(13):1306. doi:10.1001/jama.2015.2809

The JAMA Forum

How Useful Are Screening Tests?

Aaron E. Carroll, MD, MS

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JAMA. 2015;313(13):1304. doi:10.1001/jama.2015.1496

Lab Reports

Nanoparticle Delivery Approach Targets Atherosclerotic Plaques

Tracy Hampton, PhD

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JAMA. 2015;313(13):1305. doi:10.1001/jama.2015.2440

Bacteria Protect Colorectal Cancer Cells From Immune Destruction

Tracy Hampton, PhD

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JAMA. 2015;313(13):1305. doi:10.1001/jama.2015.2854

DNA Damage Continues Long After Sun Exposure

Tracy Hampton, PhD

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JAMA. 2015;313(13):1305. doi:10.1001/jama.2015.2856

Role of Genes in Obesity and Body Fat Distribution

Tracy Hampton, PhD

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JAMA. 2015;313(13):1305. doi:10.1001/jama.2015.2858

The Art of JAMA

Abstraction: Windows: Jeanne Rij-Rousseau

Jeanette M. Smith, MD

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JAMA. 2015;313(13):1298-1299. doi:10.1001/jama.2014.11667

Poetry and Medicine

Cipher

Valerie Wohlfeld

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JAMA. 2015;313(13):1375. doi:10.1001/jama.2014.18663

JAMA Revisited

The Care of the Baby鈥檚 Eyes in the Perambulator

Mary E. Baldwin, M.D.

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JAMA. 2015;313(13):1376. doi:10.1001/jama.2014.11674

JAMA Patient Page

Measles Vaccination

Jill Jin, MD, MPH

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JAMA. 2015;313(13):1386. doi:10.1001/jama.2015.1555

Comment & Response

Hypofractionated Whole Breast Irradiation for Early-Stage Breast Cancer

Lior Z. Braunstein, MD; Alphonse G. Taghian, MD, PhD

Abstract Full Text

JAMA. 2015;313(13):1370-1371. doi:10.1001/jama.2015.1641

Hypofractionated Whole Breast Irradiation for Early-Stage Breast Cancer鈥擱eply

Justin E. Bekelman, MD; Jennifer Malin, MD; Ezekiel J. Emanuel, MD, PhD

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JAMA. 2015;313(13):1371. doi:10.1001/jama.2015.1644

Low vs High Glycemic Index Diet

Jennie C. Brand-Miller, PhD; Arne Astrup, MD; Anette E. Buyken, PhD

Abstract Full Text

JAMA. 2015;313(13):1371-1372. doi:10.1001/jama.2015.2078

Low vs High Glycemic Index Diet鈥擱eply

Frank M. Sacks, MD; Lawrence J. Appel, MD; Vincent J. Carey, PhD

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JAMA. 2015;313(13):1372-1373. doi:10.1001/jama.2015.2081

Electronic Health Records and Adolescent Privacy

Charles G. Kels, JD

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JAMA. 2015;313(13):1373. doi:10.1001/jama.2015.2411

Electronic Health Records and Adolescent Privacy鈥擱eply

John Santelli, MD, MPH; Ronald Bayer, PhD; Robert Klitzman, MD

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JAMA. 2015;313(13):1373-1374. doi:10.1001/jama.2015.2414

Correction

Incorrect Absolute Risk Values

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JAMA. 2015;313(13):1374. doi:10.1001/jama.2014.16845

Misspelled Author Name

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JAMA. 2015;313(13):1374. doi:10.1001/jama.2015.1851

Incorrect Author Affiliation

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JAMA. 2015;313(13):1374. doi:10.1001/jama.2015.2179

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April 7, 2015, Vol 313, No. 13, Pages 1291-1386

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