June 23, 2015 Issue of JAMA

June 23/30, 2015, Vol 313, No. 24, Pages 2401-2508

This Week in JAMA

Highlights

Abstract Full Text

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JAMA. 2015;313(24):2401-2403. doi:10.1001/jama.2014.11819

Podcast: Cannabinoids for medical use, ICDs for patients with low ejection fraction after MI, PDE5 inhibitors and melanoma, early PDA screening and mortality in extremely preterm infants, and more.

Original Investigation

Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Acute Myocardial Infarction

Sean D. Pokorney, MD, MBA; Amy L. Miller, MD, PhD; Anita Y. Chen, MS; et al.

Abstract Full Text

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JAMA. 2015;313(24):2433-2440. doi:10.1001/jama.2015.6409

This cohort study uses registry and Medicare claims data to assess the frequency of ICD implantation within 1 year of myocardial infarction and to compare mortality in patients with vs without ICDs.

Podcast: ICD Use Among Medicare Patients After Acute MI

Editorial
Underutilization of Implantable Cardioverter-Defibrillators in Older Patients
Robert G. Hauser, MD

JAMA

Association Between Early Screening for Patent Ductus Arteriosus and In-Hospital Mortality Among Extremely Preterm Infants

Jean-Christophe Rozé, MD, PhD; Gilles Cambonie, MD, PhD; Laetitia Marchand-Martin, MS; et al.

Abstract Full Text

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JAMA. 2015;313(24):2441-2448. doi:10.1001/jama.2015.6734

This population-based cohort study reports that screening echocardiography before day 3 of life to identify patent ductus arteriosus among extremely preterm infants was associated with lower in-hospital mortality and likelihood of pulmonary hemorrhage.

Use of Phosphodiesterase Type 5 Inhibitors for Erectile Dysfunction and Risk of Malignant Melanoma

Stacy Loeb, MD, MSc; Yasin Folkvaljon, MSc; Mats Lambe, MD, PhD; et al.

Abstract Full Text

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JAMA. 2015;313(24):2449-2455. doi:10.1001/jama.2015.6604

This case-control study examines the association between use of phosphodiesterase type 5 (PDE5) inhibitors for erectile dysfunction and malignant melanoma risk.

Cannabinoids for Medical Use: A Systematic Review and Meta-analysis

Penny F. Whiting, PhD; Robert F. Wolff, MD; Sohan Deshpande, MSc; et al.

Abstract Full Text

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JAMA. 2015;313(24):2456-2473. doi:10.1001/jama.2015.6358

This meta-analysis summarizes the effectiveness of cannabis and cannabinoids for managing medical and psychotic disorders, including chemotherapy-induced nausea and vomiting, chronic pain, and mood and sleep disorders.

Editorial
Medical Marijuana: Is the Cart Before the Horse?
Deepak Cyril D'Souza, MBBS, MD; Mohini Ranganathan, MD

JAMA

Research Letter

Cannabinoid Dose and Label Accuracy in Edible Medical Cannabis Products

Ryan Vandrey, PhD; Jeffrey C. Raber, PhD; Mark E. Raber; et al.

Abstract Full Text

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JAMA. 2015;313(24):2491-2493. doi:10.1001/jama.2015.6613

This study analyzed the dose accuracy of labels from edibile medical cannabis products dispensed in 3 US cities.

Viewpoint

Scientific Discovery and the Future of Medicine

Broadly Neutralizing Antibodies and the Development of Vaccines

Barton F. Haynes, MD; Todd Bradley, PhD

Abstract Full Text

JAMA. 2015;313(24):2419-2420. doi:10.1001/jama.2015.2427

This Viewpoint discusses the importance and progress of neutralizing human immunodeficiency virus through efforts to induce broadly reactive neutralizing antibodies.

The 2015 US Dietary Guidelines: Lifting the Ban on Total Dietary Fat

Dariush Mozaffarian, MD, DrPH; David S. Ludwig, MD, PhD

Abstract Full Text

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JAMA. 2015;313(24):2421-2422. doi:10.1001/jama.2015.5941

Based on the Dietary Guidelines Advisory Committee鈥檚 recent recommendations, this Viewpoint urges the US Department of Agriculture and US Department of Health and Human Services to remove limits on total fat consumption in their 2015 Dietary Guideline to promote consumption of healthful fat.

Podcast: US Dietary Guidelines and Lifting the Total Dietary Fat Ban

FDA Regulation of Indoor Tanning Devices and Opportunities for Skin Cancer Prevention

Darren Mays, PhD, MPH; John Kraemer, JD, MPH

Abstract Full Text

JAMA. 2015;313(24):2423-2424. doi:10.1001/jama.2015.5975

This Viewpoint describes the current regulation of indoor tanning equipment and the need for a broader public health approach to prevent and reduce skin cancer caused by indoor tanning.

Unrest in Baltimore: The Role of Public Health

Leana S. Wen, MD, MSc; Joshua M. Sharfstein, MD

Abstract Full Text

JAMA. 2015;313(24):2425-2426. doi:10.1001/jama.2015.5561

This Viewpoint reflects on recent events in Baltimore and the role of public health in the immediate response, in understanding the basis of unrest, and in long-term solutions to health inequities.

A Piece of My Mind

I鈥檓 Sorry

James S. Kahn, MD

Abstract Full Text

JAMA. 2015;313(24):2427-2428. doi:10.1001/jama.2014.6507

Editorial

Underutilization of Implantable Cardioverter-Defibrillators in Older Patients

Robert G. Hauser, MD

Abstract Full Text

JAMA. 2015;313(24):2429-2430. doi:10.1001/jama.2015.6408

Medical Marijuana: Is the Cart Before the Horse?

Deepak Cyril D'Souza, MBBS, MD; Mohini Ranganathan, MD

Abstract Full Text

JAMA. 2015;313(24):2431-2432. doi:10.1001/jama.2015.6407

This Editorial discusses some of the medical and legal considerations surrounding use of medical marijuana and cannabinoid drugs.

Clinical Crossroads

Medical Marijuana for Treatment of Chronic Pain and Other Medical and Psychiatric Problems: A Clinical Review

Kevin P. Hill, MD, MHS

Abstract Full Text

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JAMA. 2015;313(24):2474-2483. doi:10.1001/jama.2015.6199

This synopsis of a medicine grand rounds conference uses an example of a patient with chronic low back pain as the basis for discussing the use of medical marijuana for treating chronic pain and other disorders.

Podcast: Medical Marijuana for Treatment of Chronic Pain and Other Problems

Editorial
Medical Marijuana: Is the Cart Before the Horse?
Deepak Cyril D'Souza, MBBS, MD; Mohini Ranganathan, MD

JAMA

From the 糖心vlog

Metformin as Initial Oral Therapy in Type 2 Diabetes

Rachel J. Stern, MD; Elizabeth J. Murphy, MD, DPhil

Abstract Full Text

JAMA. 2015;313(24):2484-2485. doi:10.1001/jama.2015.2765

JAMA Clinical Guidelines Synopsis

Perioperative 尾-Blocker Therapy

Todd Stern, MD; Adam S. Cifu, MD

Abstract Full Text

JAMA. 2015;313(24):2486-2487. doi:10.1001/jama.2015.3086

This JAMA Clinical Guidelines Synopsis article summarizes the evidence for perioperative use of 尾-blockers in patients with or at risk of developing cardiovascular disease.

Medical News & Perspectives

Novel Programs and Discoveries Aim to Combat Antibiotic Resistance

Tracy Hampton, PhD

Abstract Full Text

JAMA. 2015;313(24):2411-2413. doi:10.1001/jama.2015.4738

In the wake of increasing antimicrobial resistance threats, this article discusses some recent government initiatives and efforts by scientists, physicians, and public health officials to combat drug-resistant bacteria.

News From the Centers for Disease Control and Prevention