November 10, 2015 Issue of JAMA

November 10, 2015, Vol 314, No. 18, Pages 1889-1990 | Cardiovascular Disease

This Week in JAMA

Highlights

Abstract Full Text

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JAMA. 2015;314(18):1889-1891. doi:10.1001/jama.2014.12075

Podcast: Cardiovascular Disease Theme Issue

Original Investigation

Effect of Financial Incentives to Physicians, Patients, or Both on Lipid Levels: A Randomized Clinical Trial

David A. Asch, MD; Andrea B. Troxel, ScD; Walter F. Stewart, PhD, MPH; et al.

Abstract Full Text

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JAMA. 2015;314(18):1926-1935. doi:10.1001/jama.2015.14850

This randomized trial investigated the effects of financial incentives paid to physicians, patients, and both on low-density lipoprotein cholesterol levels among patients with high cardiovascular risk.

Podcast: Effect of Financial Incentives on Lipid Levels

Endovascular Revascularization and Supervised Exercise for Peripheral Artery Disease and Intermittent Claudication: A Randomized Clinical Trial

Farzin Fakhry, MD; Sandra Spronk, PhD; Lijckle van der Laan, MD, PhD; et al.

Abstract Full Text

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JAMA. 2015;314(18):1936-1944. doi:10.1001/jama.2015.14851

This randomized trial compares the effects of endovascular revascularization and supervised exercise vs supervised exercise alone on walking distance and quality of life among patients with peripheral artery disease and intermittent claudication.

Editorial
Erasing Disability in Peripheral Artery Disease: The Role of Endovascular Procedures and Supervised Exercise
Mary McGrae McDermott, MD

JAMA

Prevalence and Correlates of Myocardial Scar in a US Cohort

Evrim B. Turkbey, MD; Marcelo S. Nacif, MD, PhD; Mengye Guo, PhD; et al.

Abstract Full Text

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JAMA. 2015;314(18):1945-1954. doi:10.1001/jama.2015.14849

This population-based study assessed the prevalence of myocardial scarring, of which the majority were undetected by electrocardiography or clinical evaluation.

Research Letter

Consistency of Laboratory Monitoring During Initiation of Mineralocorticoid Receptor Antagonist Therapy in Patients With Heart Failure

Lauren B. Cooper, MD; Bradley G. Hammill, DrPH; Eric D. Peterson, MD, MPH; et al.

Abstract Full Text

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JAMA. 2015;314(18):1973-1975. doi:10.1001/jama.2015.11904

This study uses Medicare and Medicaid data to access the frequency of laboratory monitoring during initiation of therapy with mineralocorticoid receptor antagonists in beneficiaries with heart failure.

Viewpoint

Predicting the Overuse of PCSK-9 Inhibitors

Rene Rodriguez-Gutierrez, MD; Nilay D. Shah, PhD; Victor M. Montori, MD, MSc

Abstract Full Text

JAMA. 2015;314(18):1909-1910. doi:10.1001/jama.2015.13414

This Viewpoint anticipates widespread premature use of proprotein convertase subtilisin-kexin type 9 (PCSK-9) inhibitors in response to the challenges some patients experience taking statins and urges caution until trials and experience demonstrate the new drugs are safe.

Asymptomatic Atrial Fibrillation: The Case for Screening to Prevent Stroke

S. Ben Freedman, MBBS, PhD; Nicole Lowres, BPhty, PhD

Abstract Full Text

JAMA. 2015;314(18):1911-1912. doi:10.1001/jama.2015.9846

This Viewpoint proposes widespread screening for atrial fibrillation using accessible and inexpensive means as a public health intervention for preventing stroke.

Improving Awareness and Outcomes Related to Venous Thromboembolism

Mary Cushman, MD, MSc; Mark A. Creager, MD

Abstract Full Text

JAMA. 2015;314(18):1913-1914. doi:10.1001/jama.2015.15107

This Viewpoint discusses low public awareness about risk factors for and symptoms of venous thromboembolism and proposes quality initiatives that might improve recognition of venous thromboembolism and outcomes for patients.

Exercise Is Medicine: At Any Dose?

Thijs M. H. Eijsvogels, PhD; Paul D. Thompson, MD

Abstract Full Text

JAMA. 2015;314(18):1915-1916. doi:10.1001/jama.2015.10858

This Viewpoint discusses evidence that the beneficial effects of physical activity may vary depending on activity levels.

Evidence-Based Management of Stable Ischemic Heart Disease: Challenges and Confusion

Sripal Bangalore, MD, MHA; David J. Maron, MD; Judith S. Hochman, MD

Abstract Full Text

JAMA. 2015;314(18):1917-1918. doi:10.1001/jama.2015.11219

This Viewpoint summarizes controversies about the findings of clinical trials of revascularization for treatment of stable ischemic heart disease and argues for informing patients about the uncertainties.

A Piece of My Mind

What Now?

Catherine Spaulding, MD

Abstract Full Text

JAMA. 2015;314(18):1919-1920. doi:10.1001/jama.2015.10138

Editorial

Erasing Disability in Peripheral Artery Disease: The Role of Endovascular Procedures and Supervised Exercise

Mary McGrae McDermott, MD

Abstract Full Text

JAMA. 2015;314(18):1921-1923. doi:10.1001/jama.2015.15116

Advancing Cardiovascular Science

J. Michael Gaziano, MD; Eric D. Peterson, MD; Philip Greenland, MD

Abstract Full Text

JAMA. 2015;314(18):1924-1925. doi:10.1001/jama.2015.15590

The Rational Clinical Examination

Does This Patient With Chest Pain Have Acute Coronary Syndrome?The Rational Clinical Examination Systematic Review

Alexander C. Fanaroff, MD; Jennifer A. Rymer, MD, MBA; Sarah A. Goldstein, MD; et al.

Abstract Full Text

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JAMA. 2015;314(18):1955-1965. doi:10.1001/jama.2015.12735

This Rational Clinical Examination examines the accuracy of initial history, physical examination, electrocardiogram, and risk scores combined with the first cardiac-specific troponin for diagnosing acute coronary syndrome in the emergency department.

Podcast: Ruling Out Acute Coronary Syndrome in Patients With Chest Pain
Podcast: Using Likelihood Ratios to Understand How Chest Pain Predicts Acute Coronary Syndrome
Podcast: Management of Chronic Stable Angina in 2020

JAMA Guide to Statistics and Methods

Multiple Imputation: A Flexible Tool for Handling Missing Data

Peng Li, PhD; Elizabeth A. Stuart, PhD; David B. Allison, PhD

Abstract Full Text

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JAMA. 2015;314(18):1966-1967. doi:10.1001/jama.2015.15281

This Guide to Statistics and Methods discusses the use of multiple imputation in statistical analyses when data are missing for some participants in a clinical trial.

Podcast: JAMA Guide to Statistics and Methods

JAMA Diagnostic Test Interpretation

Exercise Treadmill Testing

Tamar S. Polonsky, MD, MSCI; Ron Blankstein, MD

Abstract Full Text

JAMA. 2015;314(18):1968-1969. doi:10.1001/jama.2015.11719

A 53-year-old man with chest pain and treated hypertension undergoes an exercise treadmill test, which demonstrates 1.5-mm ST-segment depression in inferolateral leads during recovery. How do you interpret the test result?

Medical News & Perspectives

NHSC Students to Service Awardees Begin Residencies

Julie A. Jacob, MA

Abstract Full Text

JAMA. 2015;314(18):1901-1902. doi:10.1001/jama.2015.12520

This Medical News & Perspectives story takes a look at a federal scholarship program that awards graduating medical students with up to $120 000 in loan repayment in exchange for 3 years of full-time service in an area with a shortage of primary care physicians.

The JAMA Forum