May 5, 2015 Issue of JAMA

糖心vlog

May 5, 2015, Vol 313, No. 17, Pages 1689-1770

This Week in JAMA

Highlights

Abstract Full Text

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JAMA. 2015;313(17):1689-1691. doi:10.1001/jama.2014.11721

Podcast: Spores for prevention of recurrent C difficile infection; 2 studies of newer antivirals for HCV; and more.

Original Investigation

Administration of Spores of Nontoxigenic Clostridium difficile Strain M3 for Prevention of Recurrent C difficile Infection: A Randomized Clinical Trial

Dale N. Gerding, MD; Thomas Meyer, MD; Christine Lee, MD; et al.

Abstract Full Text

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JAMA. 2015;313(17):1719-1727. doi:10.1001/jama.2015.3725

This phase 2 randomized trial reports that spores of nontoxigenic Clostridium difficile strain M3 were well tolerated, appeared to be safe, and reduced recurrence of C difficile infection (CDI) among patients who had previously had CDI treated with metronidazole or vancomycin.

Podcast: Nontoxigenic Clostridium difficile for Prevention of Recurrent Infection

Fixed-Dose Combination Therapy With Daclatasvir, Asunaprevir, and Beclabuvir for Noncirrhotic Patients With HCV Genotype 1 Infection

Fred Poordad, MD; William Sievert, MD; Lindsay Mollison, MD; et al.

Abstract Full Text

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JAMA. 2015;313(17):1728-1735. doi:10.1001/jama.2015.3860

This cohort study reports the effects of an oral fixed-dose regimen of daclatasvir, asunaprevir, and beclabuvir on sustained virologic response in patients without cirrhosis who had chronic hepatitis C virus infection.

Editorial
Continued Progress Against Hepatitis C Infection
Hari Conjeevaram, MD, MSc

JAMA

Daclatasvir in Combination With Asunaprevir and Beclabuvir for Hepatitis C Virus Genotype 1 Infection With Compensated Cirrhosis

Andrew J. Muir, MD; Fred Poordad, MD; Jacob Lalezari, MD; et al.

Abstract Full Text

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JAMA. 2015;313(17):1736-1744. doi:10.1001/jama.2015.3868

This open-label uncontrolled study of patients with chronic HCV genotype 1 infection and cirrhosis reports high rates of SVR₁₂ in those who received a 12-week oral fixed-dose regimen of daclatasvir, asunaprevir, and beclabuvir, with or without ribavirin.

Podcast: DCV/ASV/BCV for HCV Infection With Cirrhosis

Editorial
Continued Progress Against Hepatitis C Infection
Hari Conjeevaram, MD, MSc

JAMA

Viewpoint

Change From the Inside Out: Health Care Leaders Taking the Helm

Donald M. Berwick, MD, MPP; Derek Feeley, DBA; Saranya Loehrer, MD, MPH

Abstract Full Text

JAMA. 2015;313(17):1707-1708. doi:10.1001/jama.2015.2830

This Viewpoint discusses the need for leaders in health care to steer the next phase of health care reform.

An Affordable Care Act at Year 5: Key Issues for Improvement

Timothy Stoltzfus Jost, JD

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JAMA. 2015;313(17):1709-1710. doi:10.1001/jama.2015.2769

This Viewpoint discusses issues for improvement of the Affordable Care Act.

Podcast: An Affordable Care Act at Year 5: Key Issues for Improvement

Family Health History: The Case for Better Tools

Brandon M. Welch, MS, PhD; Willard Dere, MD; Joshua D. Schiffman, MD

Abstract Full Text

JAMA. 2015;313(17):1711-1712. doi:10.1001/jama.2015.2417

This Viewpoint discusses the importance of the family health history and the need for novel family history tools in the changing health care environment.

Improving the Safety of Epidural Steroid Injections

Honorio T. Benzon, MD; Marc A. Huntoon, MD; James P. Rathmell, MD

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JAMA. 2015;313(17):1713-1714. doi:10.1001/jama.2015.2912

This Viewpoint lists some recommendations to improve epidural steroid injections that were developed by a multidisciplinary working group.

A Piece of My Mind

The Hero in Medicine

Michael Radetsky, MD, CM

Abstract Full Text

JAMA. 2015;313(17):1715. doi:10.1001/jama.2015.3390

Editorial

Continued Progress Against Hepatitis C Infection

Hari Conjeevaram, MD, MSc

Abstract Full Text

JAMA. 2015;313(17):1716-1717. doi:10.1001/jama.2015.4368

This Viewpoint describes clinical progress in eradicating hepatitis C virus infection, but emphasizes the importance of making treatment more cost-effective and accessible to all patients.

JAMA Cardiovascular Disease Theme Issue: Call for Papers

Philip Greenland, MD; Eric D. Peterson, MD; J. Michael Gaziano, MD

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JAMA. 2015;313(17):1718. doi:10.1001/jama.2015.3049

From the 糖心vlog

Ramelteon for Prevention of Delirium in Hospitalized Older Patients

Stany M. T. Perkisas, MD; Maurits F. J. Vandewoude, MD, PhD

Abstract Full Text

JAMA. 2015;313(17):1745-1746. doi:10.1001/jama.2014.17394

JAMA Clinical Challenge

Tattoo Rash

Rotimi Ayoola, MD; William Mansour, BS; Jaspal Gujral, MBBS, MRCP, FRCP

Abstract Full Text

JAMA. 2015;313(17):1747-1748. doi:10.1001/jama.2015.0990

JAMA Diagnostic Test Interpretation

Testosterone Levels for Evaluation of Androgen Deficiency

Shehzad Basaria, MD

Abstract Full Text

JAMA. 2015;313(17):1749-1750. doi:10.1001/jama.2015.4179

Medical News & Perspectives

Unraveling the Influence of Gut Microbes on the Mind

M. J. Friedrich

Abstract Full Text

JAMA. 2015;313(17):1699-1701. doi:10.1001/jama.2015.2159

News From the Food and Drug Administration

New Anthrax Treatment Approved

Rita Rubin, MA

Abstract Full Text

JAMA. 2015;313(17):1704. doi:10.1001/jama.2015.3713

Final Guidance Issued on Abuse-Deterrent Opioids

Rita Rubin, MA

Abstract Full Text

JAMA. 2015;313(17):1704. doi:10.1001/jama.2015.4112

Black Box Warning for Anemia Drug

Rita Rubin, MA

Abstract Full Text

JAMA. 2015;313(17):1704. doi:10.1001/jama.2015.4114

Warning for Hepatitis C Treatments Given With Amiodarone

Rita Rubin, MA

Abstract Full Text

JAMA. 2015;313(17):1704. doi:10.1001/jama.2015.4116

The JAMA Forum

Innovating Care for Medicare Beneficiaries: Time for Riskier Bets and Embracing Failure

Ashish K. Jha, MD, MPH

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JAMA. 2015;313(17):1701-1702. doi:10.1001/jama.2015.2605

Lab Reports

Snail Genetic Variation Associated With Resistance to Schistosomiasis

Tracy Hampton, PhD

Abstract Full Text

JAMA. 2015;313(17):1703. doi:10.1001/jama.2015.3711

RNA Targeting Strategy Regenerates Heart Tissue in Adult Mice

Tracy Hampton, PhD

Abstract Full Text

JAMA. 2015;313(17):1703. doi:10.1001/jama.2015.4093

Study Reveals Consistent Ebola Virus Mutation Rate Between Outbreaks

Tracy Hampton, PhD

Abstract Full Text

JAMA. 2015;313(17):1703. doi:10.1001/jama.2015.4095

Germline Gene Mutation May Increase Leukemia Risk

Tracy Hampton, PhD

Abstract Full Text

JAMA. 2015;313(17):1703. doi:10.1001/jama.2015.4098

The Art of JAMA

Bay Bridge Anchorage Construction: George Booth Post

Thomas B. Cole, MD, MPH

Abstract Full Text

JAMA. 2015;313(17):1696-1697. doi:10.1001/jama.2014.11723

Poetry and Medicine

the orange rind

Andrew Thurston, MD

Abstract Full Text

JAMA. 2015;313(17):1759. doi:10.1001/jama.2015.205

JAMA Revisited

Anatomic Nomenclature

Albert C. Eycleshymer, B.S., M.D., Ph.D.

Abstract Full Text

JAMA. 2015;313(17):1760. doi:10.1001/jama.2014.11730

JAMA Patient Page

Male Infertility

James A. Kashanian, MD; Robert E. Brannigan, MD

Abstract Full Text

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JAMA. 2015;313(17):1770. doi:10.1001/jama.2015.3222

Comment & Response

Hospitalization for Pneumonia and Risk of Cardiovascular Disease

Francesco Violi, MD; Roberto Cangemi, MD, PhD; Camilla Calvieri, MD

Abstract Full Text

JAMA. 2015;313(17):1753. doi:10.1001/jama.2015.3130

Hospitalization for Pneumonia and Risk of Cardiovascular Disease鈥擱eply

Vicente F. Corrales-Medina, MD, MSc; Karina N. Alvarez, MS; Sachin Yende, MD, MS

Abstract Full Text

JAMA. 2015;313(17):1753-1754. doi:10.1001/jama.2015.3133

Sedation Protocol for Critically Ill Pediatric Patients

Kenneth E. Remy, MD

Abstract Full Text

JAMA. 2015;313(17):1754. doi:10.1001/jama.2015.3459

Sedation Protocol for Critically Ill Pediatric Patients鈥擱eply

Martha A. Q. Curley, RN, PhD; David Wypij, PhD; Michael A. Matthay, MD; et al.

Abstract Full Text

JAMA. 2015;313(17):1754-1755. doi:10.1001/jama.2015.3462

Expanding Long-term Care Options for Persons With Serious Mental Illness

Kenneth J. Dudek, MSW

Abstract Full Text

JAMA. 2015;313(17):1755. doi:10.1001/jama.2015.3497

Expanding Long-term Care Options for Persons With Serious Mental Illness

Susan Rogers, BA

Abstract Full Text

JAMA. 2015;313(17):1755-1756. doi:10.1001/jama.2015.3500

Expanding Long-term Care Options for Persons With Serious Mental Illness

Mitchell D. Feldman, MD, MPhil; Eric A. Feldman, JD, PhD; Saul Feldman, DPA

Abstract Full Text

JAMA. 2015;313(17):1756-1757. doi:10.1001/jama.2015.3494

Expanding Long-term Care Options for Persons With Serious Mental Illness

Franklin G. Miller, PhD

Abstract Full Text

JAMA. 2015;313(17):1757. doi:10.1001/jama.2015.3488

Expanding Long-term Care Options for Persons With Serious Mental Illness

David Son, MA, MS Ed

Abstract Full Text

JAMA. 2015;313(17):1757. doi:10.1001/jama.2015.3491

Expanding Long-term Care Options for Persons With Serious Mental Illness鈥擱eply

Dominic A. Sisti, PhD; Andrea G. Segal, MS; Ezekiel J. Emanuel, MD, PhD

Abstract Full Text

JAMA. 2015;313(17):1757-1758. doi:10.1001/jama.2015.3503

Correction

Incorrect Alignment and Omitted Data in Tables

Abstract Full Text

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JAMA. 2015;313(17):1758. doi:10.1001/jama.2015.2720

Revisions in Table

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JAMA. 2015;313(17):1758. doi:10.1001/jama.2015.3923

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May 5, 2015, Vol 313, No. 17, Pages 1689-1770

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