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November 2024 - July 1883

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March 24/31, 2015, Vol 313, No. 12, Pages 1185-1284

This Week in JAMA

Highlights

Abstract Full Text
free access has audio
JAMA. 2015;313(12):1185-1187. doi:10.1001/jama.2014.11651
  • Podcast: Oral antivirals for HCV/HIV coinfection, stent vs medical treatment for intracranial stenosis, a preliminary postexposure Ebola vaccine, and more.
Original Investigation

Ombitasvir, Paritaprevir Co-dosed With Ritonavir, Dasabuvir, and Ribavirin for Hepatitis C in Patients Co-infected With HIV-1: A Randomized Trial

Mark S. Sulkowski, MD; Joseph J. Eron, MD; David Wyles, MD; et al.
Abstract Full Text
free access
JAMA. 2015;313(12):1223-1231. doi:10.1001/jama.2015.1328

This randomized trial reports high rates of sustained virologic response in the first part of a open-label study of ombitasvir, paritaprevir (co-dosed with ritonavir), and dasabuvir with ribavirin for 63 patients with hepatitis C virus genotype 1 and human immunodeficiency virus 1 co-infection.

Virologic Response Following Combined Ledipasvir and Sofosbuvir Administration in Patients With HCV Genotype 1 and HIV Co-infection

Anu Osinusi, MD, MPH; Kerry Townsend, BA; Anita Kohli, MD, MS; et al.
Abstract Full Text
free access
JAMA. 2015;313(12):1232-1239. doi:10.1001/jama.2015.1373

This pilot study reports high rates of posttreatment sustained virologic response after use of combined ledipasvir and sofosbuvir among patients co-infected with hepatitis C virus genotype 1 and human immunodeficiency virus.

Effect of a Balloon-Expandable Intracranial Stent vs Medical Therapy on Risk of Stroke in Patients With Symptomatic Intracranial Stenosis: The VISSIT Randomized Clinical Trial

Osama O. Zaidat, MD, MS; Brian-Fred Fitzsimmons, MD; Britton Keith Woodward, MD; et al.
Abstract Full Text
free access
JAMA. 2015;313(12):1240-1248. doi:10.1001/jama.2015.1693

This randomized controlled trial compares use of a balloon-expandable stent vs medical therapy in patients with symptomatic intracranial arterial stenosis.

Preliminary Communication

Emergency Postexposure Vaccination With Vesicular Stomatitis Virus鈥揤ectored Ebola Vaccine After Needlestick

Lilin Lai, MD; Richard Davey, MD; Allison Beck, MPAS; et al.
Abstract Full Text
free access has multimedia has audio
JAMA. 2015;313(12):1249-1255. doi:10.1001/jama.2015.1995

This report summarizes the experience of 1 patient with needlestick exposure to the Ebola virus and postexposure vaccination with VSV螖G-ZEBOV.

  • Podcast: Ebola Vaccine After Needlestick
Research Letter

Salary Differences Between Male and Female Registered Nurses in the United States

Ulrike Muench, PhD, RN; Jody Sindelar, PhD; Susan H. Busch, PhD; et al.
Abstract Full Text
free access
JAMA. 2015;313(12):1265-1267. doi:10.1001/jama.2015.1487
Viewpoint

Scientific Discovery and the Future of Medicine

Harnessing RNA Interference for Therapy: The Silent Treatment

Judy Lieberman, MD, PhD; Phillip A. Sharp, PhD
Abstract Full Text
has audio
JAMA. 2015;313(12):1207-1208. doi:10.1001/jama.2015.1241

This Viewpoint discusses the role of RNA interference in therapy.

Hospital-Based Active Shooter Incidents: Sanctuary Under Fire

Eli Y. Adashi, MD, MS; Hans Gao, BA; I. Glenn Cohen, JD
Abstract Full Text
JAMA. 2015;313(12):1209-1210. doi:10.1001/jama.2015.1733

This Viewpoint discusses the evolving frequency of hospital-based active shooter incidents, the relevant legal framework, and the role of hospitals and physicians in countering this threat.

Hospital Community Benefit Programs: Increasing Benefits to Communities

Janet Corrigan, PhD, MBA; Elliott Fisher, MD, MPH; Scott Heiser, MPH
Abstract Full Text
free access
JAMA. 2015;313(12):1211-1212. doi:10.1001/jama.2015.0609

This Viewpoint describes the coordination of health-related activities at the regional level through such initiatives as accountable health communities and hospital community benefit programs.

Naltrexone Extended-Release Plus Bupropion Extended-Release for Treatment of Obesity

Susan Z. Yanovski, MD; Jack A. Yanovski, MD, PhD
Abstract Full Text
JAMA. 2015;313(12):1213-1214. doi:10.1001/jama.2015.1617

This Viewpoint discusses the potential use of combined naltrexone extended-release plus bupropion extended-release for adjunctive treatment of obesity.

A Piece of My Mind

The Absence of Something

Lawrence J. Hergott, MD
Abstract Full Text
JAMA. 2015;313(12):1215-1216. doi:10.1001/jama.2015.0874
Editorial

Hepatitis C and HIV Co-infection: Closing the Gaps

Camilla S. Graham, MD, MPH
Abstract Full Text
JAMA. 2015;313(12):1217-1218. doi:10.1001/jama.2015.1111

Endovascular Therapy for Atherosclerotic Intracranial Arterial Stenosis: Back to the Drawing Board

Marc I. Chimowitz, MBChB; Colin P. Derdeyn, MD
Abstract Full Text
JAMA. 2015;313(12):1219-1220. doi:10.1001/jama.2015.1276

This Editorial discusses the need for more randomized clinical trials to evaluate therapeutic approaches for stroke prevention in patients with intracranial arterial stenosis.

Emergency Treatment for Exposure to Ebola Virus: The Need to Fast-track Promising Vaccines

Thomas W. Geisbert, PhD
Abstract Full Text
free access
JAMA. 2015;313(12):1221-1222. doi:10.1001/jama.2015.2057
From the 糖心vlog

Surveillance of Adverse Psychiatric Medication Events

Mark Olfson, MD, MPH
Abstract Full Text
JAMA. 2015;313(12):1256-1257. doi:10.1001/jama.2014.15743
JAMA Clinical Evidence Synopsis

Systemic Corticosteroid Therapy for Acute Sinusitis

Roderick P. Venekamp, MD, PhD; Matthew J. Thompson, MBChB, MPH, DPhil; Maroeska M. Rovers, PhD
Abstract Full Text
JAMA. 2015;313(12):1258-1259. doi:10.1001/jama.2014.14418

This Clinical Evidence Synopsis discusses whether oral or parenteral corticosteroids are associated with improved clinical outcomes in patients with acute sinusitis compared to placebo or standard clinical care.

JAMA Diagnostic Test Interpretation

Evaluating Hyponatremia

David M. Cohen, MD; David H. Ellison, MD
Abstract Full Text
JAMA. 2015;313(12):1260-1261. doi:10.1001/jama.2014.13967
Medical News & Perspectives

Putting Chagas Disease on the US Radar Screen

Bridget M. Kuehn, MSJ
Abstract Full Text
JAMA. 2015;313(12):1195-1197. doi:10.1001/jama.2015.1867
The JAMA Forum

Nudging Medical Practice Change One Regulation at a Time

Andrew B. Bindman, MD
Abstract Full Text
free access
JAMA. 2015;313(12):1197-1198. doi:10.1001/jama.2015.0546
News From the Centers for Disease Control and Prevention

Missed Fetal Alcohol Syndrome Cases

Abstract Full Text
JAMA. 2015;313(12):1201. doi:10.1001/jama.2015.1856

Controlling Tickborne Fever

Abstract Full Text
JAMA. 2015;313(12):1201. doi:10.1001/jama.2015.1858
Clinical Trials Update

Shopping Vouchers Sweeten Incentive for Pregnant Women to Quit Smoking

Anita Slomski, MA
Abstract Full Text
JAMA. 2015;313(12):1200. doi:10.1001/jama.2015.1658

Enriched Formula Supplement Aids in Pressure Ulcer Healing

Anita Slomski, MA
Abstract Full Text
JAMA. 2015;313(12):1200. doi:10.1001/jama.2015.2207

ADHD Drug Decreased Binge Eating

Anita Slomski, MA
Abstract Full Text
JAMA. 2015;313(12):1200. doi:10.1001/jama.2015.2209

Neuroprotective Agent Given Soon After Stroke Shows No Benefit

Anita Slomski, MA
Abstract Full Text
JAMA. 2015;313(12):1200. doi:10.1001/jama.2015.2211
Health Agencies Update

Medicare Covers Lung Cancer Screening for Certain Beneficiaries

Tracy Hampton, PhD
Abstract Full Text
JAMA. 2015;313(12):1199. doi:10.1001/jama.2015.1655

New Tool for Down Syndrome Research

Tracy Hampton, PhD
Abstract Full Text
JAMA. 2015;313(12):1199. doi:10.1001/jama.2015.2193

New Drug Approved to Treat Metastatic Breast Cancer

Tracy Hampton, PhD
Abstract Full Text
JAMA. 2015;313(12):1199. doi:10.1001/jama.2015.2195
The Art of JAMA

Clown With Folded Arms: Walt Kuhn

Thomas B. Cole, MD, MPH
Abstract Full Text
JAMA. 2015;313(12):1192-1193. doi:10.1001/jama.2014.11653
Poetry and Medicine

Trumpets at Her Bedside

Margaret Roberts, MD
Abstract Full Text
JAMA. 2015;313(12):1272. doi:10.1001/jama.2014.18476
JAMA Revisited

Why Physicians Err in Diagnosis

Abstract Full Text
JAMA. 2015;313(12):1273. doi:10.1001/jama.2014.11660
JAMA Patient Page

Hypoglycemia

Amy E. Thompson, MD
Abstract Full Text
free access
JAMA. 2015;313(12):1284. doi:10.1001/jama.2015.0876
Comment & Response

Coronary Artery Disease Screening Using Coronary Computed Tomography Angiography

Louis Potier, MD, PhD; Nadia Matallah, MD; Kamel Mohammedi, MD, PhD
Abstract Full Text
JAMA. 2015;313(12):1267. doi:10.1001/jama.2015.1429

Coronary Artery Disease Screening Using Coronary Computed Tomography Angiography鈥擱eply

Joseph B. Muhlestein, MD; Donald L. Lappe, MD; Jeffrey L. Anderson, MD
Abstract Full Text
JAMA. 2015;313(12):1267-1268. doi:10.1001/jama.2015.1435

Duty Hour Reforms and Patient Outcomes

Haley Hunter-Zinck, PhD
Abstract Full Text
JAMA. 2015;313(12):1268-1269. doi:10.1001/jama.2015.1432

Treatment to Prevent Hepatitis B Virus Reactivation in Patients With Lymphoma Receiving Chemotherapy

Jihoon Baang, MD
Abstract Full Text
JAMA. 2015;313(12):1269-1270. doi:10.1001/jama.2015.1438

Duty Hour Reforms and Patient Outcomes鈥擱eply

Mitesh S. Patel, MD, MBA, MS; Dylan S. Small, PhD; Jeffrey H. Silber, MD, PhD
Abstract Full Text
JAMA. 2015;313(12):1269. doi:10.1001/jama.2015.1441

Treatment to Prevent Hepatitis B Virus Reactivation in Patients With Lymphoma Receiving Chemotherapy鈥擱eply

Tongyu Lin, MD; He Huang, MD; Xueying Li, MD
Abstract Full Text
JAMA. 2015;313(12):1270. doi:10.1001/jama.2015.1444
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2015;313(12):1189-1190. doi:10.1001/jama.2014.11652

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