In 1953, Watson and Crick ushered in the modern era of medical science. In a 1000-word report, they described 鈥淎 Structure for Deoxyribose Nucleic Acid鈥� and humbly suggested that this structure 鈥渉as novel features which are of considerable biological interest.鈥�1 Fifty years later, with completion of the sequencing of the human genome, these bookend scientific advances changed the landscape of modern biomedical science.