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November 2024 - July 1883

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July 7, 2015, Vol 314, No. 1, Pages 3-98

This Week in JAMA

Highlights

Abstract Full Text
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JAMA. 2015;314(1):3-5. doi:10.1001/jama.2014.11837
Original Investigation

Six Months vs Extended Oral Anticoagulation After a First Episode of Pulmonary Embolism: The PADIS-PE Randomized Clinical Trial

Abstract Full Text
free access has audio
JAMA. 2015;314(1):31-40. doi:10.1001/jama.2015.7046

This randomized trial compared the efficacy and safety of 6 vs 24 months of warfarin treatment for preventing recurrent thromboembolism in patients with a first episode of symptomatic unprovoked pulmonary embolism.

Trajectory of Cognitive Decline After Incident Stroke

Abstract Full Text
free access has multimedia has audio
JAMA. 2015;314(1):41-51. doi:10.1001/jama.2015.6968

This prospective cohort study reports that incident stroke among participants aged 45 years or older without cognitive impairment was associated with acute decline in cognitive function and also accelerated and persistent cognitive decline over 6 years.

Association of Cardiometabolic Multimorbidity With Mortality

Abstract Full Text
free access
JAMA. 2015;314(1):52-60. doi:10.1001/jama.2015.7008

This study uses individual participant data from the Emerging Risk Factors Collaboration to estimate reductions in life expectancy associated with cardiometabolic multimorbidity.

Female Hormonal Factors and the Risk of Endometrial Cancer in Lynch Syndrome

Abstract Full Text
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JAMA. 2015;314(1):61-71. doi:10.1001/jama.2015.6789

Using colon cancer registry data, these investigators found that in women with a mismatch repair gene mutation, hormonal factors such as age at menarche, parity, and use of hormonal contraceptives were associated with a lower risk of endometrial cancer.

Research Letter

Trends in Management for Patients With Localized Prostate Cancer, 1990-2013

Abstract Full Text
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JAMA. 2015;314(1):80-82. doi:10.1001/jama.2015.6036

This analysis uses data from the Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE) national registry to report on changes in the types of treatment patients with low-risk prostate cancer received from 1990 through 2013.

Viewpoint

Scientific Discovery and the Future of Medicine

Direct Reprogramming: Bypassing Stem Cells for Therapeutics

Abstract Full Text
has audio
JAMA. 2015;314(1):19-20. doi:10.1001/jama.2015.4504

This Viewpoint discusses advancements in direct reprogramming in the treatment of heart failure, diabetes, and hearing loss.

Parental Consent for the Use of Residual Newborn Screening Bloodspots: Respecting Individual Liberty vs Ensuring Public Health

Abstract Full Text
JAMA. 2015;314(1):21-22. doi:10.1001/jama.2015.6175

Striking a balance between public health research based on residual newborn screening blood spots and preserving parental rights to consent their use is the focus of this Viewpoint.

Ideological Anachronism Involving Needle and Syringe Exchange Programs: Lessons From the Indiana HIV Outbreak

Abstract Full Text
JAMA. 2015;314(1):23-24. doi:10.1001/jama.2015.6303

This Viewpoint examines federal and state syringe access policies in light of a recent HIV outbreak among injection drug users.

The Role of Physicians in the Era of Predictive Analytics

Abstract Full Text
JAMA. 2015;314(1):25-26. doi:10.1001/jama.2015.6177

This Viewpoint unravels predictive analytics, a necessary component of setting clinical guidelines based on populations of patients, but stop short in estimating individual risk.

A Piece of My Mind

Stopping Time

Abstract Full Text
JAMA. 2015;314(1):27-28. doi:10.1001/jama.2015.1674
Editorial

Stroke and Cognitive Decline

Abstract Full Text
JAMA. 2015;314(1):29-30. doi:10.1001/jama.2015.7149
JAMA Clinical Evidence Synopsis

Long-term vs Short-term Therapy With Vitamin K Antagonists for Symptomatic Venous Thromboembolism

Abstract Full Text
JAMA. 2015;314(1):72-73. doi:10.1001/jama.2015.2693

This JAMA Clinical Evidence Synopsis describes the association of long-term duration vs short-term duration of vitamin K antagonist therapy among patients with venous thromboembolism.

JAMA Diagnostic Test Interpretation

Computed Tomographic Pulmonary Angiography for Pulmonary Embolism

Abstract Full Text
JAMA. 2015;314(1):74-75. doi:10.1001/jama.2015.4970

This article analyzes diagnostic testing methods for a patient with suspected pulmonary embolism.

From The Medical Letter on Drugs and Therapeutics

Edoxaban (Savaysa)—The Fourth New Oral Anticoagulant

Abstract Full Text
JAMA. 2015;314(1):76-77. doi:10.1001/jama.2015.7098

This From the Medical Letter article reviews the pharmacokinetics and indications for edoxaban, an oral anticoagulant for the treatment of venous thromoboembolism and prevention of stroke in patients with AF.

Medical News & Perspectives

Varmus Returns to His Roots in Cancer Genetics

Abstract Full Text
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JAMA. 2015;314(1):13-14. doi:10.1001/jama.2015.4231

Former NIH Director Harold Varmus, MD, discusses his career, cancer research, and a new role at the Weill Cornell Medical College in New York City.

News From the Food and Drug Administration

Diabetes Drug Warning

Abstract Full Text
JAMA. 2015;314(1):17. doi:10.1001/jama.2015.6849

New Therapies for Irritable Bowel Syndrome

Abstract Full Text
JAMA. 2015;314(1):17. doi:10.1001/jama.2015.6855

Drug Approved for Rare Lung Disease

Abstract Full Text
JAMA. 2015;314(1):17. doi:10.1001/jama.2015.7107

Label Confusion Leads to Errors

Abstract Full Text
JAMA. 2015;314(1):17. doi:10.1001/jama.2015.7109
The JAMA Forum

A Same-Sex Infertility Health Insurance Mandate in Maryland?

Abstract Full Text
free access
JAMA. 2015;314(1):15. doi:10.1001/jama.2015.6562
Lab Reports

Researchers Uncover Novel Spatially Defined Stem Cells

Abstract Full Text
JAMA. 2015;314(1):16. doi:10.1001/jama.2015.6691

Blocking Glutamine Metabolism Shrinks Kidney Cancers in Mice

Abstract Full Text
JAMA. 2015;314(1):16. doi:10.1001/jama.2015.7175

Acetaminophen During Pregnancy May Affect Offspring’s Testes

Abstract Full Text
JAMA. 2015;314(1):16. doi:10.1001/jama.2015.7177

Striking Similarities Between Cancerous and Normal Skin Cells

Abstract Full Text
JAMA. 2015;314(1):16. doi:10.1001/jama.2015.7178
The Art of JAMA

Garden of the Generalife in Granada: Théo van Rysselberghe

Abstract Full Text
JAMA. 2015;314(1):10-11. doi:10.1001/jama.2014.11839
Poetry and Medicine

Roentgen’s Garden

Abstract Full Text
JAMA. 2015;314(1):87. doi:10.1001/jama.2015.3206
JAMA Revisited

Modern English Usage

Abstract Full Text
JAMA. 2015;314(1):88. doi:10.1001/jama.2014.11846
JAMA Patient Page

Treatment Duration for Pulmonary Embolism

Abstract Full Text
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JAMA. 2015;314(1):98. doi:10.1001/jama.2015.7431
Comment & Response

Discordant Interpretations of Breast Biopsy Specimens by Pathologists

Abstract Full Text
JAMA. 2015;314(1):82-83. doi:10.1001/jama.2015.6224

Discordant Interpretations of Breast Biopsy Specimens by Pathologists

Abstract Full Text
JAMA. 2015;314(1):82. doi:10.1001/jama.2015.6230

Discordant Interpretations of Breast Biopsy Specimens by Pathologists—Reply

Abstract Full Text
JAMA. 2015;314(1):83-84. doi:10.1001/jama.2015.6239

Suicide Among US Military Personnel

Abstract Full Text
JAMA. 2015;314(1):84. doi:10.1001/jama.2015.5742

Suicide Among US Military Personnel—Reply

Abstract Full Text
JAMA. 2015;314(1):84-85. doi:10.1001/jama.2015.5757

Redefining Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Abstract Full Text
JAMA. 2015;314(1):85. doi:10.1001/jama.2015.5731

Redefining Myalgic Encephalomyelitis/Chronic Fatigue Syndrome—Reply

Abstract Full Text
JAMA. 2015;314(1):85-86. doi:10.1001/jama.2015.5760
Correction

Incorrect Data in Table 4

Abstract Full Text
free access
JAMA. 2015;314(1):86. doi:10.1001/jama.2015.5464

Data Errors in Table 2

Abstract Full Text
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JAMA. 2015;314(1):86. doi:10.1001/jama.2015.6072

Data Errors in Table 3 and in Text

Abstract Full Text
free access
JAMA. 2015;314(1):86. doi:10.1001/jama.2015.6074

Data Errors in Results Section

Abstract Full Text
free access
JAMA. 2015;314(1):86. doi:10.1001/jama.2015.6076
JAMA Masthead

JAMA

Abstract Full Text
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JAMA. 2015;314(1):7-8. doi:10.1001/jama.2014.11838
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