August 11, 2015 Issue of JAMA

August 11, 2015, Vol 314, No. 6, Pages 535-638

This Week in JAMA

Highlights

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JAMA. 2015;314(6):535-537. doi:10.1001/jama.2014.11907

Podcast: Testosterone and subclinical atherosclerosis, CKD screening and definitions, postmarket surveillance of medical devices, and more.

Original Investigation

Effects of Testosterone Administration for 3 Years on Subclinical Atherosclerosis Progression in Older Men With Low or Low-Normal Testosterone Levels: A Randomized Clinical Trial

Shehzad Basaria, MBBS; S. Mitchell Harman, MD, PhD; Thomas G. Travison, PhD; et al.

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JAMA. 2015;314(6):570-581. doi:10.1001/jama.2015.8881

This randomized trial tested the effects of daily testosterone vs placebo gel administered for 3 years on progression of subclinical atherosclerosis in men aged 60 years or older with low or low-normal testosterone levels.

Podcast: Testosterone and Atherosclerosis in Older Men

Variation in Dialysis Facility Referral for Kidney Transplantation Among Patients With End-Stage Renal Disease in Georgia

Rachel E. Patzer, PhD, MPH; Laura C. Plantinga, PhD, ScM; Sudeshna Paul, PhD; et al.

Abstract Full Text

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JAMA. 2015;314(6):582-594. doi:10.1001/jama.2015.8897

This population epidemiology study uses United States Renal Data System data to characterize dialysis facility鈥搇evel referral for kidney transplant evaluation in Georgia, the US state with the lowest transplantation rates, and patient and facility factors associated with referral and waitlisting.

Podcast: Referrals From Dialysis Facilities for Kidney Transplantation

Editorial
Improving Access to Kidney Transplantation: Referral Is Not Enough
Lauren M. Kucirka, PhD; Tanjala S. Purnell, PhD, MPH; Dorry L. Segev, MD, PhD

JAMA

Association Between Intermittent Hypoxemia or Bradycardia and Late Death or Disability in Extremely Preterm Infants

Christian F. Poets, MD; Robin S. Roberts, MSc; Barbara Schmidt, MD, MSc; et al.

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JAMA. 2015;314(6):595-603. doi:10.1001/jama.2015.8841

This post hoc analysis of data from a trial comparing lower and higher oxgen saturation targets among extremely preterm infants investigated associations between episodes of hypoxemia or bradycardia and late death or neurodevelopmental disability.

Editorial
Hypoxemic Episodes and Adverse Neurodevelopmental Outcome in Extremely Preterm Infants
Lex W. Doyle, MD

JAMA

Characteristics of Clinical Studies Conducted Over the Total Product Life Cycle of High-Risk Therapeutic Medical Devices Receiving FDA Premarket Approval in 2010 and 2011

Vinay K. Rathi, BA; Harlan M. Krumholz, MD, SM; Frederick A. Masoudi, MD, MSPH; et al.

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JAMA. 2015;314(6):604-612. doi:10.1001/jama.2015.8761

This study uses data from ClinicalTrials.gov and FDA documents to report the proportion of high-risk therapeutic devices approved through the FDA鈥檚 Premarket Approval pathway that undergo postapproval study, as well as characteristics of those studies.

Research Letter

Outcomes of Fresh and Cryopreserved Oocyte Donation

Vitaly A. Kushnir, MD; David H. Barad, MD, MS; David F. Albertini, PhD; et al.

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JAMA. 2015;314(6):623-624. doi:10.1001/jama.2015.7556

This study used data from the 2013 annual report of US in vitro fertilization center outcomes published by the Society for Assisted Reproductive Technology to compare live birth and cycle cancellation rates using either fresh or cryopreserved donor oocytes.

Viewpoint

Racial Bias in Health Care and Health: Challenges and Opportunities

David R. Williams, PhD, MPH; Ronald Wyatt, MD, MHA

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JAMA. 2015;314(6):555-556. doi:10.1001/jama.2015.9260

This Viewpoint describes the contribution of racial bias to disparities in health care and discusses the need to increase awareness of disparities and work toward eliminating discrimination and its adverse effects.

Chronic Kidney Disease in Older People

Andrew S. Levey, MD; Lesley A. Inker, MD, MS; Josef Coresh, MD, PhD

Abstract Full Text

JAMA. 2015;314(6):557-558. doi:10.1001/jama.2015.6753

This Viewpoint asserts that current guidelines should not be changed to require age calibration for diagnosis and classification of chronic kidney disease.

An Age-Calibrated Classification of Chronic Kidney Disease

Richard Glassock, MD; Pierre Delanaye, MD, PhD; Meguid El Nahas, MD, PhD, FRCP

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JAMA. 2015;314(6):559-560. doi:10.1001/jama.2015.6731

This Viewpoint discusses the ramifications of using a glomerular filtration rate of less than 60 mL/min/1.73 m² for patients of all ages and proteinuria (albuminuria) for chronic kidney disease classification.

Advancing Continuing Medical Education

Graham T. McMahon, MD, MMSc

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JAMA. 2015;314(6):561-562. doi:10.1001/jama.2015.7094

This Viewpoint discusses opportunities and challenges in advancing the role of continuing medical education for professional development.

Podcast: Advancing Continuing Medical Education

A Piece of My Mind

A Story I Hope Ends Up Being True

Wendy Stead, MD

Abstract Full Text

JAMA. 2015;314(6):563-564. doi:10.1001/jama.2015.5285

Editorial

Improving Access to Kidney Transplantation: Referral Is Not Enough

Lauren M. Kucirka, PhD; Tanjala S. Purnell, PhD, MPH; Dorry L. Segev, MD, PhD

Abstract Full Text

JAMA. 2015;314(6):565-567. doi:10.1001/jama.2015.8932

Hypoxemic Episodes and Adverse Neurodevelopmental Outcome in Extremely Preterm Infants

Lex W. Doyle, MD

Abstract Full Text

JAMA. 2015;314(6):568-569. doi:10.1001/jama.2015.9136

From the 糖心vlog

Young Age and Aggressive Treatment in Colon Cancer

Julia R. Berian, MD; Al B. Benson III, MD; Heidi Nelson, MD

Abstract Full Text

JAMA. 2015;314(6):613-614. doi:10.1001/jama.2015.9379

This From The 糖心vlog article discusses the treatment decision process for young adults with colorectal cancer in relation to a nationwide cohort study of treatments and prognoses reported in JAMA Surgery.

JAMA Clinical Guidelines Synopsis

Screening for Chronic Kidney Disease

Milda R. Saunders, MD, MPH; Adam Cifu, MD; Monica Vela, MD

Abstract Full Text

JAMA. 2015;314(6):615-616. doi:10.1001/jama.2015.9425

This JAMA Clinical Guidelines Synopsis summarizes the American College of Physicians鈥� 2013 clinical practice guideline for screening, monitoring, and treatment of stage 1 to 3 chronic kidney disease.

JAMA Clinical Challenge

Fatigue and an Elevated White Blood Cell Count

Meredith H. Sellers, MD; Shira N. Dinner, MD

Abstract Full Text

JAMA. 2015;314(6):617-618. doi:10.1001/jama.2015.4882

A 67-year-old woman presented with fatigue for 4 weeks; a history of type 2 diabetes mellitus, hypertension, hyperlipidemia, and allergic rhinitis; and leukocytosis with predominant granulocytes. What鈥檚 the diagnosis?

Medical News & Perspectives

Navigating the Minefields of Medicine and Journalism

Rita Rubin, MA

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JAMA. 2015;314(6):545-547. doi:10.1001/jama.2015.5221

This Medical News feature discusses the conflicts that physician-journalists may face in balancing the need to report news with standards of professionalism and their ethical obligations to patients and the public.

The JAMA Forum