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August 14, 2018, Vol 320, No. 6, Pages 519-612

This Week in JAMA

Highlights

Abstract Full Text
free access has audio
JAMA. 2018;320(6):519-521. doi:10.1001/jama.2017.12493
Original Investigation

Effect of Cell-Free DNA Screening vs Direct Invasive Diagnosis on Miscarriage Rates in Women With Pregnancies at High Risk of Trisomy 21: A Randomized Clinical Trial

Abstract Full Text
free access
JAMA. 2018;320(6):557-565. doi:10.1001/jama.2018.9396

This randomized trial compares the effects of maternal Down syndrome screening using plasma cell-free DNA (cfDNA) measures vs invasive screening on miscarriage rates among pregnant women at high risk of trisomy 21 based on first-trimester combined screening.

Fixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka: A Randomized Clinical Trial

Abstract Full Text
free access has multimedia
JAMA. 2018;320(6):566-579. doi:10.1001/jama.2018.10359

This randomized clinical trial compares the effects of a fixed low-dose triple combination antihypertensive pill vs usual care on high blood pressure control among patients with mild or moderate hypertension treated at urban hospital clinics in Sri Lanka.

Association Between Traumatic Brain Injury and Risk of Suicide

Abstract Full Text
free access
JAMA. 2018;320(6):580-588. doi:10.1001/jama.2018.10211

This cohort study uses Danish national registry data to investigate associations between traumatic brain injury and suicide in the general Danish population between 1980 and 2014.

Research Letter

BRCA1 and BRCA2 Testing in Medically Underserved Medicare Beneficiaries With Breast or Ovarian Cancer

Abstract Full Text
free access
JAMA. 2018;320(6):597-598. doi:10.1001/jama.2018.8258

This study uses US community cohort data to assess BRCA1 and BRCA2 testing among medically underserved Medicare beneficiaries with breast cancer, ovarian cancer, or both.

Trends in Use of Transcatheter Aortic Valve Replacement by Age

Abstract Full Text
free access
JAMA. 2018;320(6):598-600. doi:10.1001/jama.2018.9938

This study uses National Inpatient Sample data to characterize trends in transcatheter aortic valve replacement (TAVR) in age groups 55 years and older in the United States from 2012 to 2015.

Viewpoint

Potential Child Health Consequences of the Federal Policy Separating Immigrant Children From Their Parents

Abstract Full Text
JAMA. 2018;320(6):541-542. doi:10.1001/jama.2018.10905

This Viewpoint discusses how the separation of immigrating children from their parents can result in deleterious long-term physical and psychological effects.

Increasing Fatality Rates From Preventable Deaths in Teenagers and Young Adults

Abstract Full Text
JAMA. 2018;320(6):543-544. doi:10.1001/jama.2018.6566

This Viewpoint reviews CDC injury statistics documenting a rise in preventable fatalities in young people related to opioids, motor vehicle crashes, and firearms, and calls for policies aimed at reversing the trend.

Perinatal Marijuana Use and the Developing Child

Abstract Full Text
JAMA. 2018;320(6):545-546. doi:10.1001/jama.2018.8401

This Viewpoint assesses the literature regarding marijuana use during pregnancy and whether it is safe to use as an alternative to opioids for pain management among pregnant women.

Legal Liability of Generic vs Brand Drug Manufacturers for Inadequate Product Labels

Abstract Full Text
JAMA. 2018;320(6):547-548. doi:10.1001/jama.2018.8408

This Viewpoint uses recent case law to explore the issue of whether brand-name drug manufacturers can and should be held legally liable for medical harms from generic versions of the same drug produced by other manufacturers with identical labeling.

The Health Insurance Marketplaces

Abstract Full Text
JAMA. 2018;320(6):549-550. doi:10.1001/jama.2018.8117

This Viewpoint reviews the prospects for collapse faced by ACA-created state health insurance Marketplaces if younger and healthier people disenroll and reviews evidence that the Marketplaces are likely still stable enough to provide coverage despite rising premiums.

A Piece of My Mind

A Refugee’s Journey: Told in 55-Word Stories

Abstract Full Text
JAMA. 2018;320(6):551. doi:10.1001/jama.2018.10827

In this narrative medicine essay, the author flickers in 55-word scenarios through the life of his father who came to the United States as a Vietnamese refugee through his own life working with refugee children as a youth and now as a physician to reflect that the best of who he is resulted from his father seeking a better life.

Editorial

Low-Dose Combination Blood Pressure Pharmacotherapy to Improve Treatment Effectiveness, Safety, and Efficiency

Abstract Full Text
JAMA. 2018;320(6):552-554. doi:10.1001/jama.2018.10649

Traumatic Brain Injury and Risk of Suicide

Abstract Full Text
JAMA. 2018;320(6):554-556. doi:10.1001/jama.2018.10825
From the ÌÇÐÄvlog

Stop the Bleeding: Educating the Public

Abstract Full Text
has audio
JAMA. 2018;320(6):589-590. doi:10.1001/jama.2018.7301

This commentary discusses a randomized clinical trial published in JAMA Surgery comparing the effects of point-of-care vs video instructions vs in-person training about tourniquet use on correct tourniquet application and skill retention 3 to 9 months after hemorrhage control training.

JAMA Insights

Clinical Update

Noninvasive Prenatal Genetic Screening Using Cell-free DNA

Abstract Full Text
JAMA. 2018;320(6):591-592. doi:10.1001/jama.2018.9418

This JAMA Clinical Update reviews the use of maternal cell-free DNA (cfDNA) analysis to help screen for fetal trisomies 13, 18, 21, and others).

JAMA Clinical Evidence Synopsis

Aspirin Plus Clopidogrel vs Aspirin Alone for Preventing Cardiovascular Events Among Patients at High Risk for Cardiovascular Events

Abstract Full Text
JAMA. 2018;320(6):593-594. doi:10.1001/jama.2018.9641

This Clinical Evidence Synopsis summarizes a Cochrane review of randomized trials comparing the effects of the addition of clopidogrel to aspirin therapy vs aspirin therapy alone among patients at high risk for or with established cardiovascular disease.

Medical News & Perspectives

For Survivors of Intimate Partner Violence, Overlooked Brain Injuries Take a Toll

Abstract Full Text
JAMA. 2018;320(6):535-537. doi:10.1001/jama.2018.9051

In this Medical News article, experts discuss the importance of screening for intimate partner violence to detect traumatic brain injuries that may lead to serious cognitive deficits.

The JAMA Forum

Administrative Costs and Health Information Technology

Abstract Full Text
free access
JAMA. 2018;320(6):537-538. doi:10.1001/jama.2018.10819
News From the Centers for Disease Control and Prevention

Few Americans Hit Fitness Targets

Abstract Full Text
JAMA. 2018;320(6):540. doi:10.1001/jama.2018.10609

Fatal Sepsis Linked to Platelets

Abstract Full Text
JAMA. 2018;320(6):540. doi:10.1001/jama.2018.10994
Biotech Innovations

Prosthetic Limbs Given Proprioception

Abstract Full Text
JAMA. 2018;320(6):539. doi:10.1001/jama.2018.10869

New Nonprofit Biotech From Bill and Melinda Gates

Abstract Full Text
JAMA. 2018;320(6):539. doi:10.1001/jama.2018.11253

Oral GLP-1 Analog for Type 2 Diabetes on the Horizon

Abstract Full Text
JAMA. 2018;320(6):539. doi:10.1001/jama.2018.11254
The Arts and Medicine

Deck the Halls With Diverse Portraits

Abstract Full Text
JAMA. 2018;320(6):528-530. doi:10.1001/jama.2018.11013

This Arts and Medicine essay discusses efforts in US medical centers to develop wall portraiture that honors the full diversity of medical school classes and junior faculty.

Poetry and Medicine

Transmission

Abstract Full Text
JAMA. 2018;320(6):606. doi:10.1001/jama.2018.2646
JAMA Revisited

Foreign Letters: London

Abstract Full Text
JAMA. 2018;320(6):607. doi:10.1001/jama.2017.12512
JAMA Patient Page

Scabies

Abstract Full Text
free access
JAMA. 2018;320(6):612. doi:10.1001/jama.2018.7480

This JAMA Patient Page describes the symptoms, diagnosis, and treatment of scabies skin infestation.

Comment & Response

Power of a Trial Investigating a Low-Intensity PSA-Based Screening Intervention

Abstract Full Text
JAMA. 2018;320(6):600. doi:10.1001/jama.2018.7327

Power of a Trial Investigating a Low-Intensity PSA-Based Screening Intervention—Reply

Abstract Full Text
JAMA. 2018;320(6):600-601. doi:10.1001/jama.2018.7335

Variation in Deaths From Intentional Injury and Substance Use

Abstract Full Text
JAMA. 2018;320(6):601. doi:10.1001/jama.2018.7323

Variation in Deaths From Intentional Injury and Substance Use—Reply

Abstract Full Text
JAMA. 2018;320(6):601-602. doi:10.1001/jama.2018.7339

Neurological Symptoms in US Government Personnel in Cuba

Abstract Full Text
JAMA. 2018;320(6):602. doi:10.1001/jama.2018.8702

Neurological Symptoms in US Government Personnel in Cuba

Abstract Full Text
JAMA. 2018;320(6):602-603. doi:10.1001/jama.2018.8706

Neurological Symptoms in US Government Personnel in Cuba

Abstract Full Text
JAMA. 2018;320(6):603. doi:10.1001/jama.2018.8698

Neurological Symptoms in US Government Personnel in Cuba

Abstract Full Text
JAMA. 2018;320(6):603-604. doi:10.1001/jama.2018.8713

Neurological Symptoms in US Government Personnel in Cuba—Reply

Abstract Full Text
JAMA. 2018;320(6):604-605. doi:10.1001/jama.2018.8737
Correction

Undisclosed Conflict of Interest

Abstract Full Text
free access
JAMA. 2018;320(6):605. doi:10.1001/jama.2018.10664

Typo in the Abstract

Abstract Full Text
free access
JAMA. 2018;320(6):605. doi:10.1001/jama.2018.10727

Colposcopy Rates Reported Incorrectly

Abstract Full Text
free access
JAMA. 2018;320(6):605. doi:10.1001/jama.2018.10881
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2018;320(6):523-524. doi:10.1001/jama.2017.12494
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