February 27, 2018 Issue of JAMA

February 27, 2018, Vol 319, No. 8, Pages 745-840

This Week in JAMA

Highlights

Abstract Full Text

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JAMA. 2018;319(8):745-747. doi:10.1001/jama.2017.12251

Podcast: Bag-Mask vs Mechanical Ventilation During CPR, Meropenem-Vaborbactam vs Pip-Tazo for Complicated UTI, Varicose Veins and VTE, and more

Original Investigation

Effect of Bag-Mask Ventilation vs Endotracheal Intubation During Cardiopulmonary Resuscitation on Neurological Outcome After Out-of-Hospital Cardiorespiratory Arrest: A Randomized Clinical Trial

Patricia Jabre, MD, PhD; Andrea Penaloza, MD, PhD; David Pinero, MD; et al.

Abstract Full Text

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JAMA. 2018;319(8):779-787. doi:10.1001/jama.2018.0156

This noninferiority trial compares the effects on 28-day neurological outcomes of bag-mask vs mechanical ventilation after endotracheal intubation during cardiopulmonary resuscitation for out-of-hospital cardiac arrest (OHCA).

Editorial
Airway Management During Out-of-Hospital Cardiac Arrest
Roger J. Lewis, MD, PhD; Marianne Gausche-Hill, MD

JAMA

Effect of Meropenem-Vaborbactam vs Piperacillin-Tazobactam on Clinical Cure or Improvement and Microbial Eradication in Complicated Urinary Tract Infection: The TANGO I Randomized Clinical Trial

Keith S. Kaye, MD, MPH; Tanaya Bhowmick, MD; Symeon Metallidis, MD; et al.

Abstract Full Text

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JAMA. 2018;319(8):788-799. doi:10.1001/jama.2018.0438

This noninferiority randomized trial compares the efficacy and safety of meropenem-vaborbactam vs piperacillin-tazobactam for treatment of adults with complicated urinary tract infection.

Association Between Playing American Football in the National Football League and Long-term Mortality

Atheendar S. Venkataramani, MD, PhD; Maheer Gandhavadi, MD; Anupam B. Jena, MD, PhD

Abstract Full Text

free access has audio

JAMA. 2018;319(8):800-806. doi:10.1001/jama.2018.0140

This cohort study examines the association between career participation in professional American football and mortality risk in retirement, and it compares causes of death among career vs replacement players.

Podcast: The Health of Players of American Football

Editorial
Long-term Mortality in NFL Professional Football Players: No Significant Increase, but Questions Remain
Steven T. DeKosky, MD; Michael Jaffee, MD; Russell Bauer, PhD

JAMA

Association of Varicose Veins With Incident Venous Thromboembolism and Peripheral Artery Disease

Shyue-Luen Chang, MD; Yau-Li Huang, MD; Mei-Ching Lee, MD; et al.

Abstract Full Text

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JAMA. 2018;319(8):807-817. doi:10.1001/jama.2018.0246

This cohort study uses claims data from Taiwan鈥檚 National Health Insurance program to investigate associations between varicose veins and risk of deep venous thrombosis (DVT), pulmonary embolism (PE), and peripheral artery disease (PAD).

Research Letter

Trends in Red Blood Cell, Plasma, and Platelet Transfusions in the United States, 1993-2014

Ruchika Goel, MD, MPH; Meera R. Chappidi, MD, MPH; Eshan U. Patel, MPH; et al.

Abstract Full Text

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JAMA. 2018;319(8):825-827. doi:10.1001/jama.2017.20121

This study uses National Inpatient Sample survey data to characterize trends in red blood cell, plasma, and platelet transfusions in the United States between 1993 and 2014, a period of time during which trials were demonstrating the safety of restrictive red blood cell transfusion strategies.

Viewpoint

Are Medicaid Work Requirements Legal?

Nicholas Bagley, JD

Abstract Full Text

JAMA. 2018;319(8):763-764. doi:10.1001/jama.2018.0958

This Viewpoint discusses the legality of waivers created by US states that allow work requirements to be enforced for nondisabled Medicaid beneficiaries.

International Medical Graduates鈥擜 Critical Component of the Global Health Workforce

Joseph Nwadiuko, MD, MPH; Varshini Varadaraj, MBBS, MS, MPH; Anju Ranjit, MD, MPH

Abstract Full Text

JAMA. 2018;319(8):765-766. doi:10.1001/jama.2017.17961

This Viewpoint discusses international medical graduates practicing in the United States and Canada鈥攂enefits and drawbacks to remaining in North America or returning to their country of origin to practice.

NICE, the NHS, and Cancer Drugs

Andrew Dillon, BSc; Linda J. Landells, PhD

Abstract Full Text

JAMA. 2018;319(8):767-768. doi:10.1001/jama.2017.20552

This Viewpoint describes reforms to the ways the National Health Service (NHS) appraises cost-effectiveness and coverage of cancer drugs in England and Wales, the role of the National Institute for Health and Care Excellence (NICE) in the process, and changes in drug approval rates and access to new drugs as a result.

A Piece of My Mind

Please, Doc, Take It All This Time

Bernard E. Trappey, MD

Abstract Full Text

JAMA. 2018;319(8):769-770. doi:10.1001/jama.2018.0499

In this essay, the author struggles how to respond to a dying patient鈥檚 implicit request for the ultimate pain relief.

Editorial

Airway Management During Out-of-Hospital Cardiac Arrest

Roger J. Lewis, MD, PhD; Marianne Gausche-Hill, MD

Abstract Full Text

JAMA. 2018;319(8):771-772. doi:10.1001/jama.2018.0155

Long-term Mortality in NFL Professional Football Players: No Significant Increase, but Questions Remain

Steven T. DeKosky, MD; Michael Jaffee, MD; Russell Bauer, PhD

Abstract Full Text

JAMA. 2018;319(8):773-775. doi:10.1001/jama.2017.20885

Gabapentin Approvals, Off-Label Use, and Lessons for Postmarketing Evaluation Efforts

Joshua D. Wallach, MS, PhD; Joseph S. Ross, MD, MHS

Abstract Full Text

JAMA. 2018;319(8):776-778. doi:10.1001/jama.2017.21897

JAMA Clinical Evidence Synopsis

Gabapentin for Chronic Neuropathic Pain

Andrew Moore, DSc; Sheena Derry, MA; Philip Wiffen, MSc

Abstract Full Text

JAMA. 2018;319(8):818-819. doi:10.1001/jama.2017.21547

This Clinical Evidence Synopsis summarizes a 2017 Cochrane review on pain relief associated with use of gabapentin for patients with chronic neuropathic pain.

Editorial
Gabapentin Approvals, Off-Label Use, and Lessons for Postmarketing Evaluation Efforts
Joshua D. Wallach, MS, PhD; Joseph S. Ross, MD, MHS

JAMA

JAMA Clinical Guidelines Synopsis

Guidelines for Adult Stroke Rehabilitation and Recovery

Michelle Gittler, MD; Andrew M. Davis, MD, MPH

Abstract Full Text

JAMA. 2018;319(8):820-821. doi:10.1001/jama.2017.22036

This JAMA Clinical Guidelines Synopsis summarizes the 2016 American Heart Association/American Stroke Association guideline on adult stroke rehabilitation and recovery.

From The Medical Letter on Drugs and Therapeutics

A Two-Dose Hepatitis B Vaccine for Adults (Heplisav-B)

Abstract Full Text

JAMA. 2018;319(8):822-823. doi:10.1001/jama.2018.1097

This Medical Letter review compares a newly approved 2-dose hepatitis B virus vaccine that uses a synthetic oligonucleotide immunostimulatory adjuvant, and is licensed for use in adults, with other commercially available 3-dose vaccines.

Medical News & Perspectives

Virtual and Augmented Reality Put a Twist on Medical Education

Bridget M. Kuehn, MSJ

Abstract Full Text

has multimedia

JAMA. 2018;319(8):756-758. doi:10.1001/jama.2017.20800

This Medical News article discusses applications of augmented and virtual reality in medical education.

Video: Medical Education Incorporates Virtual Reality Into Human Anatomy Lessons

The JAMA Forum

The Good and Bad News of Health Care Employment

David M. Cutler, PhD

Abstract Full Text

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JAMA. 2018;319(8):758-759. doi:10.1001/jama.2018.1054

News From the Centers for Disease Control and Prevention

Women鈥檚 Use of ADHD Drugs Skyrockets

Bridget M. Kuehn, MSJ

Abstract Full Text

JAMA. 2018;319(8):762. doi:10.1001/jama.2018.0670

Hepatitis B Recommendations Updated

Bridget M. Kuehn, MSJ

Abstract Full Text

JAMA. 2018;319(8):762. doi:10.1001/jama.2018.0754

Clinical Trials Update

Breastfeeding Rates Improved With Financial Reward

Anita Slomski, MA

Abstract Full Text

JAMA. 2018;319(8):761. doi:10.1001/jama.2018.0827

Air Pollution May Limit Health Benefits of Walking

Anita Slomski, MA

Abstract Full Text

JAMA. 2018;319(8):761. doi:10.1001/jama.2018.1198

High-Intensity Exercise Safe in De Novo Parkinson Disease

Anita Slomski, MA

Abstract Full Text

JAMA. 2018;319(8):761. doi:10.1001/jama.2018.1200

Internet-Accessed STI Test Complements Face-to-Face Services

Anita Slomski, MA

Abstract Full Text

JAMA. 2018;319(8):761. doi:10.1001/jama.2018.1202

Stem Cell Transplantation Improves Scleroderma Outcomes

Anita Slomski, MA

Abstract Full Text

JAMA. 2018;319(8):761. doi:10.1001/jama.2018.1204

Health Agencies Update

Plant-Chemical Shows Promise for Pain Relief

Bridget Kuehn, MSJ

Abstract Full Text

JAMA. 2018;319(8):760. doi:10.1001/jama.2018.0425

Iodine Deficiency May Impair Fertility

Bridget Kuehn, MSJ

Abstract Full Text

JAMA. 2018;319(8):760. doi:10.1001/jama.2018.1291

Accelerating Clinical Gene Editing

Bridget Kuehn, MSJ

Abstract Full Text

JAMA. 2018;319(8):760. doi:10.1001/jama.2018.1292

Poetry and Medicine

Notes for a Chord

Beverly Greenspan, MD

Abstract Full Text

JAMA. 2018;319(8):834. doi:10.1001/jama.2017.13974

JAMA Revisited

Food Inspection and Food Control

Abstract Full Text

JAMA. 2018;319(8):835. doi:10.1001/jama.2017.12259

JAMA Patient Page

Sport-Related Concussion

Christopher C. Muth, MD

Abstract Full Text

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JAMA. 2018;319(8):840. doi:10.1001/jama.2018.0436

This JAMA Patient Page describes the evaluation and management of sport-related concussion.

Comment & Response

Drug Interactions With Non鈥�Vitamin K Oral Anticoagulants

Yan Li, BSPharm, MSc; Shujie Dong, BSPharm, MSc; Rene Soria-Saucedo, MD, PhD, MPH

Abstract Full Text

JAMA. 2018;319(8):827-828. doi:10.1001/jama.2017.20830

Drug Interactions With Non鈥�Vitamin K Oral Anticoagulants

Sunny A. Linnebur, PharmD; Joseph T. Hanlon, PharmD, MS

Abstract Full Text

JAMA. 2018;319(8):828-829. doi:10.1001/jama.2017.20834

Drug Interactions With Non鈥揤itamin K Oral Anticoagulants

Sara R. Vazquez, PharmD, BCPS, CACP; Arthur Allen, PharmD, CACP

Abstract Full Text

JAMA. 2018;319(8):829-830. doi:10.1001/jama.2017.20842

Drug Interactions With Non鈥揤itamin K Oral Anticoagulants

Anne-Laure Sennesael, MSc; Séverine Henrard, PhD; Anne Spinewine, PhD

Abstract Full Text

JAMA. 2018;319(8):829. doi:10.1001/jama.2017.20846

Drug Interactions With Non鈥揤itamin K Oral Anticoagulants

Nan Wang, PharmD, MA; Erika Giblin, PharmD; Jo Ellen Rodgers, PharmD

Abstract Full Text

JAMA. 2018;319(8):830. doi:10.1001/jama.2017.20850

Drug Interactions With Non鈥揤itamin K Oral Anticoagulants鈥擱eply

Shang-Hung Chang, MD, PhD; Ming-Shien Wen, MD; Chang-Fu Kuo, MD, PhD

Abstract Full Text

JAMA. 2018;319(8):830-831. doi:10.1001/jama.2017.20854

The Evidence for Cognitive Behavioral Therapy

Lorenzo Lorenzo-Luaces, PhD

Abstract Full Text

JAMA. 2018;319(8):831-832. doi:10.1001/jama.2017.20826

The Evidence for Cognitive Behavioral Therapy

Arnold A. P. van Emmerik, PhD; Kim de Jong, PhD; Stefan G. Hofmann, PhD

Abstract Full Text

JAMA. 2018;319(8):832. doi:10.1001/jama.2017.20838

The Evidence for Cognitive Behavioral Therapy鈥擱eply

Falk Leichsenring, DSc; Christiane Steinert, PhD

Abstract Full Text

JAMA. 2018;319(8):832-833. doi:10.1001/jama.2017.20858

Correction

Errors in Text and Supplement

Abstract Full Text

free access

JAMA. 2018;319(8):833. doi:10.1001/jama.2017.21113

Omitted Disclosure of Potential Conflicts of Interest

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JAMA. 2018;319(8):833. doi:10.1001/jama.2018.0621

Incorrect Unit in Laboratory Value

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JAMA. 2018;319(8):833. doi:10.1001/jama.2018.0981

Missing Corresponding Author Information and Error in Supplement Note

Abstract Full Text

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JAMA. 2018;319(8):833. doi:10.1001/jama.2018.1034

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February 27, 2018, Vol 319, No. 8, Pages 745-840

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