February 13, 2018 Issue of JAMA

February 13, 2018, Vol 319, No. 6, Pages 525-624

This Week in JAMA

Highlights

Abstract Full Text

free access has audio

JAMA. 2018;319(6):525-527. doi:10.1001/jama.2017.12229

Podcast: Excluding PE in Low-Risk ED Patients, Screening for Ovarian Cancer, COIs in Nutrition Research, and more

Original Investigation

Effect of the Pulmonary Embolism Rule-Out Criteria on Subsequent Thromboembolic Events Among Low-Risk Emergency Department Patients: The PROPER Randomized Clinical Trial

Yonathan Freund, MD, PhD; Marine Cachanado, MsC; Adeline Aubry, MD; et al.

Abstract Full Text

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JAMA. 2018;319(6):559-566. doi:10.1001/jama.2017.21904

This crossover cluster鈥搑andomized clinical noninferiority trial compared the safety of using pulmonary embolism rule-out criteria (PERC) vs a conventional strategy (D-dimer and CTPA) for excluding the diagnosis of pulmonary embolism (PE) among emergency department patients with low clinical probability of PE.

Editorial
Utility of a Clinical Prediction Rule to Exclude Pulmonary Embolism Among Low-Risk Emergency Department Patients: Reason to PERC Up
Jeffrey A. Kline, MD

JAMA

Effect of a Quality Improvement Intervention on Clinical Outcomes in Patients in India With Acute Myocardial Infarction: The ACS QUIK Randomized Clinical Trial

Mark D. Huffman, MD, MPH; Padinhare P. Mohanan, MD, DM; Raji Devarajan, MS; et al.

Abstract Full Text

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JAMA. 2018;319(6):567-578. doi:10.1001/jama.2017.21906

This cluster randomized, stepped-wedge clinical trial compares the effect of a quality improvement tool kit vs usual care on 30-day major adverse cardiovascular events in patients with acute myocardial infarction (AMI) in Kerala, India.

Editorial
Improving Evidence for Implementation of Guideline-Based Care in Low- and Middle-Income Countries
Christopher B. Granger, MD; Denis Xavier, MD

JAMA

Association of the Affordable Care Act Dependent Coverage Provision With Prenatal Care Use and Birth Outcomes

Jamie R. Daw, MSc; Benjamin D. Sommers, MD, PhD

Abstract Full Text

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JAMA. 2018;319(6):579-587. doi:10.1001/jama.2018.0030

This study determines whether the dependent coverage provision of the Affordable Care Act was associated with changes in payment for birth, prenatal care, and birth outcomes among married and unmarried women.

Research Letter

Gender and Byline Placement of Co-first Authors in Clinical and Basic Science Journals With High Impact Factors

Erin Aakhus, MD, MSHP; Nandita Mitra, PhD; Ebbing Lautenbach, MD, MPH, MSCE; et al.

Abstract Full Text

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JAMA. 2018;319(6):610-611. doi:10.1001/jama.2017.18672

This study describes the byline order of gender-discordant co-first authors in 10 clinical and basic science journals with high impact factors.

Paid Family and Childbearing Leave Policies at Top US Medical Schools

Nicholas S. Riano, MAS; Eleni Linos, MD, DrPH; Erin C. Accurso, PhD; et al.

Abstract Full Text

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JAMA. 2018;319(6):611-614. doi:10.1001/jama.2017.19519

This study characterizes variations in duration, salary support, policy clarity, and constraints or prerequisites for childbearing and family leave policies at 12 top-tier US medical schools.

US Preventive Services Task Force

Recommendation Statement

Screening for Ovarian Cancer: US Preventive Services Task Force Recommendation Statement

US Preventive Services Task Force

Abstract Full Text

free access has audio

JAMA. 2018;319(6):588-594. doi:10.1001/jama.2017.21926

This 2018 Recommendation Statement from the US Preventive Services Task Force recommends against screening for ovarian cancer in asymptomatic women (D recommendation).

Podcast: USPSTF Recommendation: Screening for Ovarian Cancer

Editorial
Screening for Ovarian Cancer in Asymptomatic Women
Karen H. Lu, MD

JAMA
The Yet Unrealized Promise of Ovarian Cancer Screening
Charles W. Drescher, MD; Garnet L. Anderson, PhD

JAMA Oncol
Is There a Future for Ovarian Cancer Screening?
Steven A. Narod, MD

JAMA Intern Med

Evidence Report

Screening for Ovarian Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Jillian T. Henderson, PhD; Elizabeth M. Webber, MS; George F. Sawaya, MD

Abstract Full Text

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JAMA. 2018;319(6):595-606. doi:10.1001/jama.2017.21421

This systematic review to support the 2018 update of the US Preventive Services Task Force Recommendation Statement on screening for ovarian cancer summarizes published evidence on the benefits and harms of ovarian cancer screening for average-risk, asymptomatic women.

Editorial
Screening for Ovarian Cancer in Asymptomatic Women
Karen H. Lu, MD

JAMA
The Yet Unrealized Promise of Ovarian Cancer Screening
Charles W. Drescher, MD; Garnet L. Anderson, PhD

JAMA Oncol
Is There a Future for Ovarian Cancer Screening?
Steven A. Narod, MD

JAMA Intern Med

Viewpoint

Language, Science, and Politics: The Politicization of Public Health

Lawrence O. Gostin, JD

Abstract Full Text

JAMA. 2018;319(6):541-542. doi:10.1001/jama.2017.21763

This Viewpoint provides historical context for advice given by the US Department of Health and Human Services in 2017 to the CDC to avoid particular words in 2019 budget requests and argues that scientific innovation can flourish only when it is protected from political interference.

Ascent to the Summit of the CME Pyramid

Robin Stevenson, MD; Donald E. Moore Jr, PhD

Abstract Full Text

JAMA. 2018;319(6):543-544. doi:10.1001/jama.2017.19791

This Viewpoint proposes a framework for thinking about outcomes of continuing medical education (CME) activities, including identification of professional practice gaps and improvement of clinical competence, clinician performance, and patient and community health outcomes.

Evolution of Continuing Medical Education: Promoting Innovation Through Regulatory Alignment

Graham T. McMahon, MD, MMSc; Susan E. Skochelak, MD

Abstract Full Text

JAMA. 2018;319(6):545-546. doi:10.1001/jama.2017.19954

This Viewpoint discusses efforts by the ACCME and AMA to develop new rules that allow physicians to collect continuing medical education credits using new technologies and in a streamlined way.

Disclosures in Nutrition Research: Why It Is Different

John P. A. Ioannidis, MD, DSc; John F. Trepanowski, PhD

Abstract Full Text

JAMA. 2018;319(6):547-548. doi:10.1001/jama.2017.18571

In this Viewpoint, John Ioannidis argues that nutrition researchers should be required to disclose relevant dietary advocacy, activism, practices, and personal preferences given indirect financial benefits they may realize from offering dietary advice and the relative ease with which they can promote their personal beliefs in diet through science.

A Piece of My Mind

I Solemnly Share

Rahael Gupta, MS

Abstract Full Text

JAMA. 2018;319(6):549-550. doi:10.1001/jama.2017.22135

In this essay, a young medical student describes her struggle with depression and how the experience of vulnerability has bred a deep compassion for her patients and peers.

Editorial

Utility of a Clinical Prediction Rule to Exclude Pulmonary Embolism Among Low-Risk Emergency Department Patients: Reason to PERC Up

Jeffrey A. Kline, MD

Abstract Full Text

JAMA. 2018;319(6):551-553. doi:10.1001/jama.2017.21901

Improving Evidence for Implementation of Guideline-Based Care in Low- and Middle-Income Countries

Christopher B. Granger, MD; Denis Xavier, MD

Abstract Full Text

JAMA. 2018;319(6):554-556. doi:10.1001/jama.2017.21905

Screening for Ovarian Cancer in Asymptomatic Women

Karen H. Lu, MD

Abstract Full Text

JAMA. 2018;319(6):557-558. doi:10.1001/jama.2017.21894

JAMA Guide to Statistics and Methods

The Stepped-Wedge Clinical Trial: Evaluation by Rolling Deployment

Susan S. Ellenberg, PhD

Abstract Full Text

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JAMA. 2018;319(6):607-608. doi:10.1001/jama.2017.21993

This JAMA Guide to Statistics and Methods discusses the stepped-wedge apporach to cluster randomized clinical trial design, in which clusters are randomized to the order in which they receive the experimental regimen.

Podcast: JAMA Guide to Statistics and Methods
Podcast: Understanding Stepped-Wedge Clinical Trials
JAMAevidence: Guide to Statistics and Methods: The Stepped-Wedge Clinical Trial: Evaluation by Rolling Deployment

Medical News & Perspectives

Simple Models and Ice Bucket Challenge Fuel Progress in ALS Treatment

Bridget M. Kuehn, MSJ

Abstract Full Text

JAMA. 2018;319(6):535-537. doi:10.1001/jama.2017.20704

This Medical News story discusses recent progress in ALS research fueled by work in basic model systems and funding from the Ice Bucket Challenge.

The JAMA Forum

A New Year鈥檚 Wish on Opioids

Joshua M. Sharfstein, MD

Abstract Full Text

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JAMA. 2018;319(6):537-538. doi:10.1001/jama.2018.0058

News From the Centers for Disease Control and Prevention

State Restrictions of e-Cigarette Use Has Slowed

Rita Rubin, MA

Abstract Full Text

JAMA. 2018;319(6):540. doi:10.1001/jama.2018.0121

Obesity Tied to Income, Education, But Not in All Populations

Rita Rubin, MA

Abstract Full Text

JAMA. 2018;319(6):540. doi:10.1001/jama.2018.0381

Biotech Innovations

Urine Test for Tuberculosis in Development

Jennifer Abbasi

Abstract Full Text

JAMA. 2018;319(6):539. doi:10.1001/jama.2018.0241

Hemophilia Gene Therapies Show Promise

Jennifer Abbasi

Abstract Full Text

JAMA. 2018;319(6):539. doi:10.1001/jama.2018.0524

The Arts and Medicine

In Shadow and Light鈥擨mages of Transformation Through Breast Cancer

Jennifer R. Henneman, MA, PhD

Abstract Full Text

JAMA. 2018;319(6):532-534. doi:10.1001/jama.2017.21752

This Arts and Medicine essay reviews Edges of Light: Images of Breast Transformation, a traveling exhibit of photographs and poetry documenting a literature and humanities professor鈥檚 journey through breast cancer treatment and reconstruction.

Poetry and Medicine