June 26, 2018 Issue of JAMA

June 26, 2018, Vol 319, No. 24, Pages 2453-2566

This Week in JAMA

Highlights

Abstract Full Text

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JAMA. 2018;319(24):2453-2455. doi:10.1001/jama.2017.12427

Podcast: Fruquintinib for Refractory Metastatic CRC, Abortion Facility Type and Procedural Complications, Screening for Osteoporosis, and more

Original Investigation

Effect of Fruquintinib vs Placebo on Overall Survival in Patients With Previously Treated Metastatic Colorectal Cancer: The FRESCO Randomized Clinical Trial

Jin Li, MD; Shukui Qin, MD; Rui-Hua Xu, MD, PhD; et al.

Abstract Full Text

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JAMA. 2018;319(24):2486-2496. doi:10.1001/jama.2018.7855

This randomized clinical trial compares the effects of fruquintinib, a vascular endothelial growth factor receptor (VEGFR) inhibitor, vs placebo on overall survival among patients with metastatic colorectal cancer whose disease progressed on treatment or who could not tolerate standard treatment because of toxic effects.

Association of Facility Type With Procedural-Related Morbidities and Adverse Events Among Patients Undergoing Induced Abortions

Sarah C. M. Roberts, DrPH; Ushma D. Upadhyay, PhD, MPH; Guodong Liu, PhD; et al.

Abstract Full Text

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JAMA. 2018;319(24):2497-2506. doi:10.1001/jama.2018.7675

This study uses a national private insurance claims database data to compare abortion-related morbidity and adverse events among women undergoing induced abortions in office-based settings (including abortion clinics) vs ambulatory surgical centers.

Editorial
Abortion-Related Adverse Events by Facility Type: Reassurance From a National Analysis
Carolyn L. Westhoff, MD, MS; Anne R. Davis, MD, MPH

JAMA

Annual Risk of Major Bleeding Among Persons Without Cardiovascular Disease Not Receiving Antiplatelet Therapy

Vanessa Selak, PhD; Andrew Kerr, MD; Katrina Poppe, PhD; et al.

Abstract Full Text

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JAMA. 2018;319(24):2507-2520. doi:10.1001/jama.2018.8194

This cohort study estimates population risk of major bleeding among community-dwelling people in New Zealand without cardiovascular disease (CVD) and not taking antiplatelet therapy in an attempt to define the harms associated with guidelines recommending aspirin for primary prevention of CVD.

Research Letter

Prevalence of Missed Opportunities for HIV Testing Among Persons Unaware of Their Infection

Cyprian Wejnert, PhD; Joseph Prejean, PhD; Brooke Hoots, PhD; et al.

Abstract Full Text

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JAMA. 2018;319(24):2555-2557. doi:10.1001/jama.2018.7611

This study uses National HIV Behavioral Surveillance survey data to estimate the proportion of men who have sex with men and persons who inject drugs unaware of their HIV infection who missed opportunities for testing and diagnosis in clinical settings.

US Preventive Services Task Force

Recommendation Statement

Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement

US Preventive Services Task Force

Abstract Full Text

free access has audio

JAMA. 2018;319(24):2521-2531. doi:10.1001/jama.2018.7498

This 2018 Recommendation Statement from the US Preventive Services Task Force recommends screening for osteoporosis with bone measurement testing to prevent osteoporotic fractures in women 65 years and older (B recommendation) and in postmenopausal women younger than 65 years at increased risk of osteoporosis (B recommendation), and concludes that current evidence is insufficient to assess the benefits and harms of screening to prevent osteoporotic fractures in men (I statement).

Podcast: USPSTF Recommendation Statement: Screening for Osteoporosis to Prevent Fractures

Editorial
Screening for Osteoporosis
Jane A. Cauley, DrPH

JAMA
Osteoporosis Screening鈥�2 Steps May Be Too Much for Women Younger Than 65 Years
Margaret L. Gourlay, MD, MPH

JAMA Intern Med

Evidence Report

Screening to Prevent Osteoporotic Fractures: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Meera Viswanathan, PhD; Shivani Reddy, MD, MSc; Nancy Berkman, PhD; et al.

Abstract Full Text

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JAMA. 2018;319(24):2532-2551. doi:10.1001/jama.2018.6537

This systematic review to support the 2018 US Preventive Services Task Force Recommendation Statement on osteoporosis screening summarizes published evidence on the benefits and harms of screening and treatment to prevent osteoporotic fractures in adults 40 years and older.

Editorial
Screening for Osteoporosis
Jane A. Cauley, DrPH

JAMA
Osteoporosis Screening鈥�2 Steps May Be Too Much for Women Younger Than 65 Years
Margaret L. Gourlay, MD, MPH

JAMA Intern Med

Viewpoint

QALYs in 2018鈥擜dvantages and Concerns

Peter J. Neumann, ScD; Joshua T. Cohen, PhD

Abstract Full Text

JAMA. 2018;319(24):2473-2474. doi:10.1001/jama.2018.6072

This Viewpoint reviews the rationale for measuring health outcomes using quality-adjusted life-years (QALYs) and discusses the advantages and limitations of the measure and its role in attempts to define and promote the practice of high-value medicine.

Global Budgets in Maryland: Assessing Results to Date

Joshua M. Sharfstein, MD; Elizabeth A. Stuart, PhD; Joseph Antos, PhD

Abstract Full Text

JAMA. 2018;319(24):2475-2476. doi:10.1001/jama.2018.5871

This Viewpoint discusses the unique approach to health care reform implemented in Maryland, which has a diverse population served by rural, suburban, and urban hospitals including 2 major academic health centers.

Health Care Reforms in India

K. Srinath Reddy, MD, DM

Abstract Full Text

JAMA. 2018;319(24):2477-2478. doi:10.1001/jama.2018.5284

This Viewpoint discusses the efforts India has been taking as it works toward establishing universal health coverage.

A Piece of My Mind

Making Room

Jennifer Lycette, MD

Abstract Full Text

JAMA. 2018;319(24):2479-2480. doi:10.1001/jama.2018.7438

In this narrative medicine essay, an oncologist empathizes with a patient who upon learning that her cancer had returned asks about fertility preservation, a wish for children that mirrored the oncologists own desire for children after several miscarriages.

Editorial

Abortion-Related Adverse Events by Facility Type: Reassurance From a National Analysis

Carolyn L. Westhoff, MD, MS; Anne R. Davis, MD, MPH

Abstract Full Text

JAMA. 2018;319(24):2481-2483. doi:10.1001/jama.2018.7906

Screening for Osteoporosis

Jane A. Cauley, DrPH

Abstract Full Text

JAMA. 2018;319(24):2483-2485. doi:10.1001/jama.2018.5722

JAMA Clinical Challenge

A Woman With Fever and Lymphadenopathy

Jiacai Cho, MBBS, MCRP, MMed; Sze Chin Jong, MBBS, MCRP, MMed; Siok Bian Ng, MBBS, FRCPA

Abstract Full Text

JAMA. 2018;319(24):2552-2553. doi:10.1001/jama.2018.6469

A Chinese woman developed fever, cervical lymphadenopathy, cytopenias, and elevated LFTs and ferritin levels, with a positive anti-dsDNA test and hemophagocytosis on bone marrow biopsy. What would you do next?

Medical News & Perspectives

Amid Osteoporosis Treatment Crisis, Experts Suggest Addressing Patients鈥� Bisphosphonate Concerns

Jennifer Abbasi

Abstract Full Text

JAMA. 2018;319(24):2464-2466. doi:10.1001/jama.2018.7097

This Medical News article discusses how fears of rare adverse effects associated with osteoporosis medications are driving a treatment crisis.

Despite Educational Campaigns, US Infants Are Still Dying Due to Unsafe Sleep Conditions

Rita Rubin, MA

Abstract Full Text

JAMA. 2018;319(24):2466-2468. doi:10.1001/jama.2018.6097

This Medical News story examines why US infants continue to die because of unsafe sleep conditions.

News From the Centers for Disease Control and Prevention

Insect Borne Disease Threat Grows

Bridget M. Kuehn, MSJ

Abstract Full Text

JAMA. 2018;319(24):2471. doi:10.1001/jama.2018.7441

Rise in Fall-Related Deaths

Bridget M. Kuehn, MSJ

Abstract Full Text

JAMA. 2018;319(24):2471. doi:10.1001/jama.2018.7978

Clinical Trials Update

Bath Emollients Offer Little Added Benefit in Pediatric Eczema

Anita Slomski, MA

Abstract Full Text

JAMA. 2018;319(24):2470. doi:10.1001/jama.2018.7938

Phone App No Help in Controlling Hypertension

Anita Slomski, MA

Abstract Full Text

JAMA. 2018;319(24):2470. doi:10.1001/jama.2018.8167

MDMA-Assisted Psychotherapy for PTSD

Anita Slomski, MA

Abstract Full Text

JAMA. 2018;319(24):2470. doi:10.1001/jama.2018.8168

A尾-Clearing Drug Fails to Slow Alzheimer Disease

Anita Slomski, MA

Abstract Full Text

JAMA. 2018;319(24):2470. doi:10.1001/jama.2018.8169

Neurocognitive Benefits from Breastfeeding May Not Endure

Anita Slomski, MA

Abstract Full Text

JAMA. 2018;319(24):2470. doi:10.1001/jama.2018.8170

Health Agencies Update

NIH-Sponsored Trial of Universal Influenza Vaccine

Rita Rubin, MA

Abstract Full Text

JAMA. 2018;319(24):2469. doi:10.1001/jama.2018.7886

Phone Apps for Patients With Diabetes

Rita Rubin, MA

Abstract Full Text

JAMA. 2018;319(24):2469. doi:10.1001/jama.2018.8164

Federal Rule Overrides State Telemedicine Restrictions

Rita Rubin, MA

Abstract Full Text

JAMA. 2018;319(24):2469. doi:10.1001/jama.2018.8166

Poetry and Medicine

Handwashing 0347

Ron Louie, MD

Abstract Full Text

JAMA. 2018;319(24):2561. doi:10.1001/jama.2018.0094

JAMA Revisited

Doctors in Congress

Abstract Full Text

JAMA. 2018;319(24):2562. doi:10.1001/jama.2017.12435

JAMA Patient Page

Screening for Osteoporosis to Prevent Fractures

Jill Jin, MD, MPH

Abstract Full Text

free access

JAMA. 2018;319(24):2566. doi:10.1001/jama.2018.8361

This JAMA Patient Page describes the US Preventive Services Task Force recommendations on screening for osteoporosis to prevent fractures.

Comment & Response

Patent Foramen Ovale and Risk of Perioperative Stroke

Gianluca Rigatelli, MD, PhD, EBIR; Marco Zuin, MS

Abstract Full Text

JAMA. 2018;319(24):2557. doi:10.1001/jama.2018.5732

Patent Foramen Ovale and Risk of Perioperative Stroke鈥擱eply

Pauline Yeung Ng, MD; Timothy T. Houle, PhD; Matthias Eikermann, MD, PhD

Abstract Full Text

JAMA. 2018;319(24):2557-2558. doi:10.1001/jama.2018.5736

Price Setting for Physician Services

Mark T. Silvestri, MD, MHS

Abstract Full Text

JAMA. 2018;319(24):2558. doi:10.1001/jama.2018.4661

Price Setting for Physician Services鈥擱eply

Austin B. Frakt, PhD; Michael E. Chernew, PhD

Abstract Full Text

JAMA. 2018;319(24):2558-2559. doi:10.1001/jama.2018.4669

Virtual Care as a Specialty

Lee H. Schwamm, MD

Abstract Full Text

JAMA. 2018;319(24):2559. doi:10.1001/jama.2018.5666

Virtual Care as a Specialty

John F. Pearson, MD; Jorge A. Rodriguez, MD; Charles Safran, MD, MS

Abstract Full Text

JAMA. 2018;319(24):2559-2560. doi:10.1001/jama.2018.5670

Virtual Care as a Specialty鈥擱eply

Michael Nochomovitz, MD; Rahul Sharma, MD, MBA

Abstract Full Text

JAMA. 2018;319(24):2560. doi:10.1001/jama.2018.5674

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June 26, 2018, Vol 319, No. 24, Pages 2453-2566

Recommendation Statement

Evidence Report

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