This randomized clinical trial compares the effects of coaching patients with chronic kidney disease to increase vs maintain or reduce their free water intake on change in their estimated glomerular filitration rate at 12 months.
This randomized clinical trial compares the effect of immediate postresection intravesical instillation of gemcitabine vs instillation of saline on cancer recurrence in patients with suspected low-grade non–muscle-invasive urothelial cancer.
This meta-analysis compares the effects of vasopressin with vs without catecholamine vasopressors on atrial fibrillation, mortality, stroke, and other adverse outcomes in patients with distributive shock.
This study examines crowdfunding campaigns on GoFundMe and YouCaring sponsored by US-based businesses engaging in direct-to-consumer marketing of stem cell interventions to discover whether the benefits and risks are mentioned in the campaign descriptions.
This 2018 updated Recommendation Statement from the US Preventive Services Task Force concludes that clinicians should not screen for prostate cancer in men aged 55 to 69 years who do not express a preference for screening (C recommendation) and recommends against PSA-based screening in men 70 years and older (D recommendation).
This systematic review to support the 2018 US Preventive Services Task Force Recommendation Statement on screening for prostate cancer summarizes published evidence on the benefits and harms of prostate cancer screening and treatment and the use of prebiopsy risk calculators to discriminate between men with and without high-risk cancer.
This Viewpoint discusses what it will take to transform retail or minute clinics, such as those at CVS/Aetna, into fully integrated components of larger health systems that offer patient-centered, cost-aligned, value-based health care.
In this Viewpoint, JCAHO leaders discuss the challenges of value-based payment reform in instances when performance measures cannot capture clinically valid but difficult-to-measure exclusions, and urges payers and policy makers to take measurement error into account when setting payment rules.
This Viewpoint uses the case of Jahi McGrath, a physically healthy adolescent in a brain-dead state since a catastrophic surgical complication in 2013, to discuss the differences between neurologic and legal definitions of brain death and to explain conflicts between families' and physicians’ understandings of prognosis that arise as a result.
This Viewpoint calls out the contribution of growth in health care workforce to higher health care costs, and emphasizes the need to find efficiencies in the current national workforce and resist additional hiring growth as a mechanism to slow growth in spending.
In this narrative medicine essay, an anesthesiologist shares her grief and takes stock of what she has and loves after the loss of a young patient in the operationg room.
This Expression of Concern warns of potential validity issues with articles written by Brian Wansink and published in JAMA and the ÌÇÐÄvlog journals.
This commentary discusses an article published in JAMA Surgery using claims data from the Healthcare Cost and Utilization Project’s State Inpatient Database to assess the variation in care quality and postoperative outcomes among US bariatric centers of excellence.
This Medical News article discusses a recent analysis of 10 clinical trials of omega-3 fatty acid supplements for heart health.
This Arts and Medicine essay reviews The Good Doctor, an ABC television series that follows the fictional adventures of Shaun Murphy, a first-year surgical intern with autism spectrum disorder, as he learns to be a functioning part of a medical team and hospital system in his first year of surgical internship.
This JAMA Patient Page discusses the US Preventive Services Task Force’s recommendations on screening for prostate cancer in asymptomatic men.