Bruce M. Psaty, MD, PhD; Olaf M. Dekkers, MD, PhD; Richard S. Cooper, MD
JAMA. 2018;320(8):751-752. doi:10.1001/jama.2018.8377
This Viewpoint compares the strengths and weaknesses of precision-medicine and preventive-medicine models for treating disease driven by genetics and disease driven by lifestyle and toxic environments.
Richard Platt, MD, MS; Tracy Lieu, MD, MPH
JAMA. 2018;320(8):753-754. doi:10.1001/jama.2018.9342
This Viewpoint reviews the advantages of data enclaves, secure hosting environments that permit remote investigator access to confidential health system data, as a solution to facilitate data sharing for clinical and health services research while minimizing concerns about data reuse and security.
Timothy M. Uyeki, MD, MPH, MPP; Robert A. Fowler, MD, MDCM, MSc; William A. Fischer II, MD
JAMA. 2018;320(8):755-756. doi:10.1001/jama.2018.8113
This Viewpoint reviews advances in the surveillance, diagnosis, and treatment of influenza since the 1918 pandemic, and identifies key clinical questions to address in advance of the next outbreak, including optimal treatment for hospitalized and critically ill patients and those with secondary bacterial pneumonia.
Paul G. Shekelle, MD, PhD
JAMA. 2018;320(8):757-758. doi:10.1001/jama.2018.9660
This Viewpoint reviews recent progress and challenges in the evolution of clinical practice guidelines, from 2011 National Academy of Medicine (NAM) guidance for creation of trustworthy guidelines through the 2018 demise of the National Guideline Clearinghouse (NGC), and calls for increased attention to conflicts of interest among guidelines developers and the need for more regular and frequent guideline updates.