November 20, 2018 Issue of JAMA

November 20, 2018, Vol 320, No. 19, Pages 1955-2050

This Week in JAMA

Highlights

Abstract Full Text

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JAMA. 2018;320(19):1955-1957. doi:10.1001/jama.2017.12636

Podcast: Physical Activity Guidelines, ICU Nursing Burnout, AKI and PCKD Therapy Trials, and more

Original Investigation

Caring for the Critically Ill Patient

Effects of a Multimodal Program Including Simulation on Job Strain Among Nurses Working in Intensive Care Units: A Randomized Clinical Trial

Radia El Khamali, RN; Atika Mouaci, RN; Sabine Valera, RN; et al.

Abstract Full Text

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JAMA. 2018;320(19):1988-1997. doi:10.1001/jama.2018.14284

This randomized clinical trial compares the effects of a multimodal program involving education and role-play in simulated patient care sequences vs no intervention on work-related stress and work-related outcomes among nurses working at adult intensive care units (ICUs) in France.

Video: Conference Presentation: Effects of a Multimodal Program Including Simulation on Job Strain Among Nurses Working in Intensive Care Units: A Randomized Clinical Trial

Podcast: Observations From ICU Patients We Thought Were Asleep, but Were Not

Editorial
Reducing the Stress on Clinicians Working in the ICU
Jennifer B. Seaman, PhD, RN; Taya R. Cohen, PhD; Douglas B. White, MD, MAS

JAMA

Caring for the Critically Ill Patient

Effect of Human Recombinant Alkaline Phosphatase on 7-Day Creatinine Clearance in Patients With Sepsis-Associated Acute Kidney Injury: A Randomized Clinical Trial

Peter Pickkers, MD, PhD; Ravindra L. Mehta, MD; Patrick T. Murray, MD; et al.

Abstract Full Text

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JAMA. 2018;320(19):1998-2009. doi:10.1001/jama.2018.14283

This randomized clinical trial determines the optimal therapeutic dose, effect on kidney function, and adverse effects of human recombinant alkaline phosphatase in patients who are critically ill with sepsis-associated acute kidney injury.

Video: Conference Presentation: Effect of Human Recombinant Alkaline Phosphatase on 7-Day Creatinine Clearance in Patients With Sepsis-Associated Acute Kidney Injury: A Randomized Trial

Effect of Lanreotide on Kidney Function in Patients With Autosomal Dominant Polycystic Kidney Disease: The DIPAK 1 Randomized Clinical Trial

Esther Meijer, PhD; Folkert W. Visser, PhD; Rene M. M. van Aerts, MD; et al.

Abstract Full Text

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JAMA. 2018;320(19):2010-2019. doi:10.1001/jama.2018.15870

This randomized clinical trial compares the effect of adding the somatostatin analogue lanreotide to standard care vs standard care alone on change in estimated glomerular filtration rate (eGFR) in patients with autosomal dominant polycystic kidney disease (PCKD).

Research Letter

Association Between the Experimental Kickoff Rule and Concussion Rates in Ivy League Football

Douglas J. Wiebe, PhD; Bernadette A. D鈥橝lonzo, MPH; Robin Harris; et al.

Abstract Full Text

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JAMA. 2018;320(19):2035-2036. doi:10.1001/jama.2018.14165

This before-after study investigates changes in concussion among Ivy League football players after implementation of a 2016 rule change intended to land more kickoffs in the end zone and reduce player injury.

Joint Prevalence of Sitting Time and Leisure-Time Physical Activity Among US Adults, 2015-2016

Emily N. Ussery, PhD; Janet E. Fulton, PhD; Deborah A. Galuska, PhD; et al.

Abstract Full Text

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JAMA. 2018;320(19):2036-2038. doi:10.1001/jama.2018.17797

This study uses 2015-2016 National Health and Nutrition Examination Survey data to assess prevalence of daily sitting time and weekly leisure-time physical activity among US adults.

Special Communication

The Physical Activity Guidelines for Americans

Katrina L. Piercy, PhD, RD; Richard P. Troiano, PhD; Rachel M. Ballard, MD, MPH; et al.

Abstract Full Text

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JAMA. 2018;320(19):2020-2028. doi:10.1001/jama.2018.14854

This Special Communication from the US Department of Health and Human Services summarizes key guidelines and recommendations in the Physical Activity Guidelines for Americans, 2nd edition.

Video: Highlights Of The 2018 Physical Activity Guidelines for Americans, 2nd Edition
Video: Physical Activity Guidelines for Americans, 2nd Edition

Editorial
New Physical Activity Guidelines: A Call to Activity for Clinicians and Patients
Paul D. Thompson, MD; Thijs M. H. Eijsvogels, PhD

JAMA

Viewpoint

Physical Activity Guidelines for Health and Prosperity in the United States

Brett P. Giroir, MD; Don Wright, MD, MPH

Abstract Full Text

JAMA. 2018;320(19):1971-1972. doi:10.1001/jama.2018.16998

This Viewpoint from the US Assistant Secretary for Health discusses the Physical Activity Guidelines for Americans, 2nd edition, and proposes ways in which the medical care system, new technologies, workplace initiatives, and enhanced youth participation in sports can promote physical activity.

Editorial
New Physical Activity Guidelines: A Call to Activity for Clinicians and Patients
Paul D. Thompson, MD; Thijs M. H. Eijsvogels, PhD

JAMA

The New Age of Patient Autonomy: Implications for the Patient-Physician Relationship

Madison K. Kilbride, PhD; Steven Joffe, MD, MPH

Abstract Full Text

JAMA. 2018;320(19):1973-1974. doi:10.1001/jama.2018.14382

This Viewpoint discusses the changing role of physicians in an era when patients are self-educated about their conditions and can order tests online, evolving from physician paternalism to a role of patient consultant, procedural expert, and gatekeeper to second-line follow-up services.

Health Apps and Health Policy: What Is Needed?

David W. Bates, MD, MSc; Adam Landman, MD; David M. Levine, MD, MPH, MA

Abstract Full Text

JAMA. 2018;320(19):1975-1976. doi:10.1001/jama.2018.14378

This Viewpoint discusses ways in which health apps can be improved and regulated by the US Food and Drug Administration to improve health in patients and confidence in the apps by physicians.

Alternative State-Level Financing for Hepatitis C Treatment鈥擳he 鈥淣etflix Model鈥�

Mark R. Trusheim, MS; William M. Cassidy, MD; Peter B. Bach, MD

Abstract Full Text

JAMA. 2018;320(19):1977-1978. doi:10.1001/jama.2018.15782

This Viewpoint discusses a 鈥淣etflix鈥� subscription model of drug payment being investigated by Louisiana for hepatitis C (HCV) drugs, in which a statewide coalition of payers would pay subscription fees over a fixed number of years for HCV drugs to treat all state residents and for efforts by the manufacturers to enhance treatment rates through patient outreach.

A Piece of My Mind

Solving the Silence

Olivia J. Killeen, MD; Laura Bridges, DO

Abstract Full Text

JAMA. 2018;320(19):1979-1980. doi:10.1001/jama.2018.15686

In this narrative medicine essay, 2 female physicians recount uncomfortable moments during their training when patients made inappropriate comments, and they challenge teaching physicians to address such comments in real time to educate patients and defend an equitable learning environment for trainees.

Editorial

Reducing the Stress on Clinicians Working in the ICU

Jennifer B. Seaman, PhD, RN; Taya R. Cohen, PhD; Douglas B. White, MD, MAS

Abstract Full Text

JAMA. 2018;320(19):1981-1982. doi:10.1001/jama.2018.14285

New Physical Activity Guidelines: A Call to Activity for Clinicians and Patients

Paul D. Thompson, MD; Thijs M. H. Eijsvogels, PhD

Abstract Full Text

JAMA. 2018;320(19):1983-1984. doi:10.1001/jama.2018.16070

Scientific Misconduct and Medical Journals

Howard Bauchner, MD; Phil B. Fontanarosa, MD, MBA; Annette Flanagin, RN, MA; et al.

Abstract Full Text

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JAMA. 2018;320(19):1985-1987. doi:10.1001/jama.2018.14350

JAMA Clinical Challenge

Hyperpigmented Macule on the Palm and Diminished Sensation

Reda Awali, MD; Pranatharthi H. Chandrasekar, MD

Abstract Full Text

JAMA. 2018;320(19):2029-2030. doi:10.1001/jama.2018.14701

A 25-year-old Bangladeshi immigrant presented with a hyperpigmented, hypoesthetic macule on her palm and an enlarged ulnar nerve. A previous biopsy of the palm lesion had revealed perineural granulomas with inflammatory cells that stained negative for acid-fast bacilli and fungi. What would you do next?

JAMA Diagnostic Test Interpretation

Vibration-Controlled Transient Elastography for Diagnosing Cirrhosis and Staging Hepatic Fibrosis

Julius Wilder, MD, PhD; Steve S. Choi, MD; Cynthia A. Moylan, MD, MHS

Abstract Full Text

JAMA. 2018;320(19):2031-2032. doi:10.1001/jama.2018.13073

A 68-year-old man has an undetectable hepatitis C (HCV) viral load, normal liver function tests, and an elevated vibration-controlled transient elastography (VCTE) measure after 12 weeks of antiviral treatment for HCV with stage 2 fibrosis by biopsy. How do you interpret the results?

Medical News & Perspectives

RNAi Rollercoaster Begins to Reap Therapies

Bridget M. Kuehn

Abstract Full Text

JAMA. 2018;320(19):1963-1965. doi:10.1001/jama.2018.14898

This Medical News article discusses the discovery of RNAi and developments in its use as a therapeutic tool to treat genetic diseases.

News From the Food and Drug Administration

FDA Joins New Effort to Strengthen Medical Device Cybersecurity

Rebecca Voelker, MSJ

Abstract Full Text

JAMA. 2018;320(19):1970. doi:10.1001/jama.2018.17834

Will Naloxone Become Available OTC?

Rebecca Voelker, MSJ

Abstract Full Text

JAMA. 2018;320(19):1970. doi:10.1001/jama.2018.17836

Blood Group Genotyping Test Goes Beyond A, B, and O

Rebecca Voelker, MSJ

Abstract Full Text

JAMA. 2018;320(19):1970. doi:10.1001/jama.2018.17838

The JAMA Forum

Progress in Primary Care鈥擣rom Alma-Ata to Astana

Dave A. Chokshi, MD, MSc; Louise Cohen, MPH

Abstract Full Text

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JAMA. 2018;320(19):1965-1966. doi:10.1001/jama.2018.16957

Bench to Bedside

For Difficult-to-Model Brain Diseases, Brain Organoids Come to the Rescue

Feyza Sancar, PhD

Abstract Full Text

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JAMA. 2018;320(19):1966-1968. doi:10.1001/jama.2018.15972

Podcast: For Difficult-to-Model Brain Diseases, Brain Organoids Come to the Rescue

Global Health

Mapping Yellow Fever Virus in Brazil

M.J. Friedrich

Abstract Full Text

JAMA. 2018;320(19):1969. doi:10.1001/jama.2018.17155

Global Hunger on the Rise as Climate Extremes Increase

M.J. Friedrich

Abstract Full Text

JAMA. 2018;320(19):1969. doi:10.1001/jama.2018.17909

Guidelines for Ending Childhood and Adolescent Tuberculosis

M.J. Friedrich

Abstract Full Text

JAMA. 2018;320(19):1969. doi:10.1001/jama.2018.17910

Poetry and Medicine

I Pray

Carol Snyder Halberstadt

Abstract Full Text

JAMA. 2018;320(19):2044. doi:10.1001/jama.2018.7869

JAMA Revisited

Current Comment

Abstract Full Text

JAMA. 2018;320(19):2045. doi:10.1001/jama.2017.12666

JAMA Patient Page

Endoscopic Retrograde Cholangiopancreatography

Ioana Baiu, MD, MPH; Brendan Visser, MD

Abstract Full Text

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JAMA. 2018;320(19):2050. doi:10.1001/jama.2018.14481

This JAMA Patient Page describes the endoscopic retrograde cholangiopancreatography procedure and its purposes.

Comment & Response

Validity of the qSOFA Score in Low- and Middle-Income Countries

Joseph M. Lewis, MSc, MRCP, DTMH; Marc Henrion, PhD; Jamie Rylance, PhD, MRCP, DTMH

Abstract Full Text

JAMA. 2018;320(19):2038-2039. doi:10.1001/jama.2018.14473

Validity of the qSOFA Score in Low- and Middle-Income Countries鈥擱eply

Kristina E. Rudd, MD, MPH; Christopher W. Seymour, MD, MSc; Derek C. Angus, MD, MPH

Abstract Full Text

JAMA. 2018;320(19):2039-2040. doi:10.1001/jama.2018.14477

Maryland鈥檚 Hospital Global Budget Program

Eric T. Roberts, PhD; Ateev Mehrotra, MD, MPH; Michael E. Chernew, PhD

Abstract Full Text

JAMA. 2018;320(19):2040. doi:10.1001/jama.2018.14370

Maryland鈥檚 Hospital Global Budget Program鈥擱eply

Joshua M. Sharfstein, MD; Elizabeth A. Stuart, PhD; Joseph Antos, PhD

Abstract Full Text

JAMA. 2018;320(19):2040-2041. doi:10.1001/jama.2018.14374

Odds Ratios vs Risk Ratios

Jeffrey Sonis, MD, MPH

Abstract Full Text

JAMA. 2018;320(19):2041. doi:10.1001/jama.2018.14417

Odds Ratios vs Risk Ratios鈥擱eply

Edward C. Norton, PhD; Bryan E. Dowd, PhD; Matthew L. Maciejewski, PhD

Abstract Full Text

JAMA. 2018;320(19):2041-2042. doi:10.1001/jama.2018.14421

Breakthrough Therapy Designation for New Drugs

Edward J. Benz Jr, MD

Abstract Full Text

JAMA. 2018;320(19):2042. doi:10.1001/jama.2018.15938

Breakthrough Therapy Designation for New Drugs鈥擱eply

Jeremy Puthumana, MS; Joshua D. Wallach, PhD, MS; Joseph S. Ross, MD, MHS

Abstract Full Text

JAMA. 2018;320(19):2042-2043. doi:10.1001/jama.2018.15942

November 2024 - July 1883

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Year

Issue

November 20, 2018, Vol 320, No. 19, Pages 1955-2050

Caring for the Critically Ill Patient

Caring for the Critically Ill Patient

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