糖心vlog

This Viewpoint reviews the growth of the Choosing Wisely campaign from its inception in 2012 into an international movement and outlines advances in evidence and implementation that will be necessary for the effort to have more widespread, durable effects on the quality, safety, and value of health care.

This Viewpoint points out that many definitions of low-value health care are based exclusively on efficacy or harm, and argues that inclusion of cost and cost-effectiveness measures is necessary to define health service value.

This Viewpoint summarizes a 2017 NASEM Roundtable on Genomics and Precision Health that shared experiences of US health systems with use of genome sequencing for clinical and research applications and that explored how the sequencing programs might advance models for data sharing and collaborative implementation research; generate evidence regarding the benefits, harms, and value of precision medicine; and reduce disparities through partnerships with diverse populations.

In this Viewpoint, John Ioannidis and colleagues discuss the challenges and potential benefits of defining what is 鈥渉ealthy鈥� in an era of precision medicine, when defining normal will require that each person be assigned to an increasingly narrow and granular reference population.