July 27, 2021 Issue of JAMA

July 27, 2021, Vol 326, No. 4, Pages 291-366

This Week in JAMA

Audio Highlights

Abstract Full Text

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JAMA. 2021;326(4):e2018049. doi:10.1001/jama.2020.18049

Podcast: Heart Failure Quality Improvement RCT, 7 vs 14 Days of Antibiotics for Male UTI, Does This Patient Have Hypertension?, and more

Original Investigation

Effect of a Hospital and Postdischarge Quality Improvement Intervention on Clinical Outcomes and Quality of Care for Patients With Heart Failure With Reduced Ejection Fraction: The CONNECT-HF Randomized Clinical Trial

Adam D. DeVore, MD, MHS; Bradi B. Granger, PhD, RN; Gregg C. Fonarow, MD; et al.

Abstract Full Text

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JAMA. 2021;326(4):314-323. doi:10.1001/jama.2021.8844

This cluster randomized trial evaluates the effect of a hospital and postdischarge quality improvement intervention vs usual care on time to heart failure rehospitalization or death, and quality of care, among patients with heart failure and reduced ejection fraction in the US.

Editorial
Prioritizing Dissemination and Implementation Science in Cardiometabolic Medicine: CONNECTing the Dots
Ankeet S. Bhatt, MD, MBA; Scott D. Solomon, MD; Muthiah Vaduganathan, MD, MPH

JAMA

Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical Trial

Dimitri M. Drekonja, MD, MS; Barbara Trautner, MD, PhD; Carla Amundson, MA; et al.

Abstract Full Text

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JAMA. 2021;326(4):324-331. doi:10.1001/jama.2021.9899

This randomized clinical trial assesses the effect of 14-day antibiotic treatment vs 7 days of antibiotic treatment plus 7 days of placebo among afebrile men with urinary tract infection.

Editorial
Shorter Courses of Antibiotics for Urinary Tract Infection in Men
Daniel J. Morgan, MD, MS; K. C. Coffey, MD, MPH

JAMA

Frequency of Thrombocytopenia and Platelet Factor 4/Heparin Antibodies in Patients With Cerebral Venous Sinus Thrombosis Prior to the COVID-19 Pandemic

Mayte Sánchez van Kammen, MD; Mirjam R. Heldner, MD, MSc; Justine Brodard, MSc; et al.

Abstract Full Text

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JAMA. 2021;326(4):332-338. doi:10.1001/jama.2021.9889

This retrospective analysis examined the frequency of thrombocytopenia and heparin-induced thrombocytopenia among patients with cerebral venous sinus thrombosis (CVST) before COVID-19 to help elucidate the association of ChAdOx1 nCoV-19 and Ad26.COV2.S vaccines and CVST thrombocytopenia.

Research Letter

Effect of Systemic Hydrocortisone Initiated 7 to 14 Days After Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years鈥� Corrected Age: Follow-up of a Randomized Clinical Trial

Nienke M. Halbmeijer, MD; Wes Onland, PhD; Filip Cools, PhD; et al.

Abstract Full Text

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JAMA. 2021;326(4):355-357. doi:10.1001/jama.2021.9380

This follow-up to the STOP-BPD randomized clinical trial, which investigated the efficacy and safety of systemic hydrocortisone treatment initiated 7 to 14 days after birth in ventilator-dependent, very preterm infants in the Netherlands and Belgium at 36 weeks鈥� postmenstrual age, examines the prespecified composite of death and neurodevelopmental impairment among these infants at 2 years鈥� corrected age.

Viewpoint

Lay Epidemiology and Vaccine Acceptance

Sudhakar V. Nuti, MD, MSc; Katrina Armstrong, MD, MSCE

Abstract Full Text

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JAMA. 2021;326(4):301-302. doi:10.1001/jama.2021.11130

This Viewpoint discusses how family, friends, social media, the larger public, and others can influence an individual鈥檚 health care decisions, including COVID-19 vaccination, and offers ways in which to build confidence in vaccination among groups that may be skeptical of getting the vaccine.

COVID-19: Beyond Tomorrow

Potential COVID-19 Endgame Scenarios: Eradication, Elimination, Cohabitation, or Conflagration?

Aaron Kofman, MD; Rami Kantor, MD; Eli Y. Adashi, MD, MS

Abstract Full Text

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JAMA. 2021;326(4):303-304. doi:10.1001/jama.2021.11042

This Viewpoint considers 4 possible scenarios鈥攅radication, elimination, cohabitation, and conflagration鈥攆or the resolution of the COVID-19 pandemic, depending on vaccination rates, viral variants, and deadly disease waves.

The Growing Problem of Out-of-Pocket Costs and Affordability in Employer-Sponsored Insurance

Meredith B. Rosenthal, PhD

Abstract Full Text

JAMA. 2021;326(4):305-306. doi:10.1001/jama.2021.11166

This Viewpoint describes the problem of rising out-of-pocket costs for individuals with employer-sponsored insurance, the causes of this issue, and possible solutions.

A Piece of My Mind

The Race We Already Lost

Eileen P. Storey, MD

Abstract Full Text

JAMA. 2021;326(4):307-308. doi:10.1001/jama.2021.11214

In this narrative medicine essay, a resident in medicine and pediatrics learns in her last year of medical school that her physician father has metastatic liver cancer and hopes that for just a day or a little longer the 2 could share the title doctor.

Editorial

Shorter Courses of Antibiotics for Urinary Tract Infection in Men

Daniel J. Morgan, MD, MS; K. C. Coffey, MD, MPH

Abstract Full Text

JAMA. 2021;326(4):309-310. doi:10.1001/jama.2021.11120

Prioritizing Dissemination and Implementation Science in Cardiometabolic Medicine: CONNECTing the Dots

Ankeet S. Bhatt, MD, MBA; Scott D. Solomon, MD; Muthiah Vaduganathan, MD, MPH

Abstract Full Text

JAMA. 2021;326(4):311-313. doi:10.1001/jama.2021.9847

The Rational Clinical Examination

Does This Adult Patient Have Hypertension?The Rational Clinical Examination Systematic Review

Anthony J. Viera, MD, MPH; Yuichiro Yano, MD, PhD; Feng-Chang Lin, PhD; et al.

Abstract Full Text

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JAMA. 2021;326(4):339-347. doi:10.1001/jama.2021.4533

This Rational Clinical Examination systematic review summarizes studies that examined the accuracy of current methods of blood pressure measurement, including home and office monitoring, compared with ambulatory blood pressure monitoring as the reference standard for diagnosing hypertension in patients not receiving treatment for hypertension.

JAMAevidence: The Rational Clinical Examination: Does This Adult Patient Have Hypertension? Interview With Dr Anthony Joseph Viera

JAMA Insights

Women's Health

Anabolic Therapy for Osteoporosis

Kristine E. Ensrud, MD, MPH; John T. Schousboe, MD, PhD

Abstract Full Text

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JAMA. 2021;326(4):350-351. doi:10.1001/jama.2021.0233

This JAMA Insights reviews the use of anabolic medications to reduce the risk of osteoporosis-related fractures, including teriparatide, abaloparatide, and romosozumab.

Podcast: Anabolic Therapy for Osteoporosis

Lipoprotein(a) and Cardiovascular Diseases

Hannah Miksenas, BA; James L. Januzzi Jr, MD; Pradeep Natarajan, MD, MMSc

Abstract Full Text

JAMA. 2021;326(4):352-353. doi:10.1001/jama.2021.3632

This JAMA Insights Clinical Update discusses various clinical aspects of lipoprotein(a), including association with cardiovascular disease risk, measurement, guideline recommendations, and emerging therapies.

JAMA Clinical Guidelines Synopsis

Screening for Hepatitis C Virus

Hannah C. Wenger, MD; Adam S. Cifu, MD; Arthur Y. Kim, MD

Abstract Full Text

JAMA. 2021;326(4):348-349. doi:10.1001/jama.2020.27041

This JAMA Clinical Guidelines Synopsis summarizes the American Association for the Study of Liver Diseases/Infectious Diseases Society of America 2019 guideline update on screening for hepatitis C virus.

Medical News & Perspectives

Confronting High HIV Rates Among Transgender Women With Empowerment and Gender Affirmation

Bridget M. Kuehn, MSJ

Abstract Full Text

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JAMA. 2021;326(4):295-297. doi:10.1001/jama.2021.10598

This Medical News article describes the social and structural factors that drive exceptionally high HIV infection rates among transgender women.

Podcast: July 2021 Medical News Summary

News From the Centers for Disease Control and Prevention

Excess Deaths From End-Stage Kidney Disease Early in Pandemic

Bridget M. Kuehn, MSJ

Abstract Full Text

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JAMA. 2021;326(4):300. doi:10.1001/jama.2021.11312

Resurgence of Pertussis Linked With Switch to Acellular Vaccine

Bridget M. Kuehn, MSJ

Abstract Full Text

JAMA. 2021;326(4):300. doi:10.1001/jama.2021.11153

Clinical Trials Update

Tai Chi Reduces Waist Size Among Older Adults

Anita Slomski

Abstract Full Text

JAMA. 2021;326(4):299. doi:10.1001/jama.2021.10833

MDMA-Assisted Therapy Highly Effective for PTSD

Anita Slomski

Abstract Full Text

JAMA. 2021;326(4):299. doi:10.1001/jama.2021.11748

Fewer Cardiovascular Events With Intensive Blood Pressure Control

Anita Slomski

Abstract Full Text

JAMA. 2021;326(4):299. doi:10.1001/jama.2021.11749

Filgotinib Induces and Maintains Ulcerative Colitis Remission

Anita Slomski

Abstract Full Text

JAMA. 2021;326(4):299. doi:10.1001/jama.2021.11750

Health Agencies Update

Ending Structural Racism in Federally Funded Research

Rita Rubin, MA

Abstract Full Text

JAMA. 2021;326(4):298. doi:10.1001/jama.2021.10972

Internet Access as a Social Determinant of Health

Rita Rubin, MA

Abstract Full Text

JAMA. 2021;326(4):298. doi:10.1001/jama.2021.11733

Higher Medicare Payments for In-home COVID-19 Vaccinations

Rita Rubin, MA

Abstract Full Text

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JAMA. 2021;326(4):298. doi:10.1001/jama.2021.11734

The Arts and Medicine

Renal Columns

Zachary David Levy, MD; Alison Rose Ohringer, MPH, MS; Bruce Haight, MD

Abstract Full Text

JAMA. 2021;326(4):294. doi:10.1001/jama.2021.4061

This Arts and Medicine feature contains a kidney-themed crossword puzzle.

Poetry and Medicine

Time Limits

Blair L. Bigham, MD, MSc

Abstract Full Text

JAMA. 2021;326(4):361. doi:10.1001/jama.2021.8081

JAMA Revisited

Problems on Campus

Abstract Full Text

JAMA. 2021;326(4):362. doi:10.1001/jama.2020.18050

JAMA Patient Page

Cardiac Rehabilitation

Jayson R. Baman, MD; Shaundeep Sekhon, MD; Kameswari Maganti, MD

Abstract Full Text

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JAMA. 2021;326(4):366. doi:10.1001/jama.2021.5952

This JAMA Patient Page describes the goals of cardiac rehabilitation, its 3 phases, and which patients benefit from it.

Comment & Response

Effect of Ventral vs Dorsal Spinal Surgery in Patients With Cervical Spondylotic Myelopathy

Hiroyuki Inose, MD, PhD; Toshitaka Yoshii, MD, PhD; Atsushi Okawa, MD, PhD

Abstract Full Text

JAMA. 2021;326(4):357-358. doi:10.1001/jama.2021.7262

Effect of Ventral vs Dorsal Spinal Surgery in Patients With Cervical Spondylotic Myelopathy

Long Shao, MD, PhD; Xiang-Dong Wu, MD; Wei Huang, MD, PhD

Abstract Full Text

JAMA. 2021;326(4):358. doi:10.1001/jama.2021.7265

Effect of Ventral vs Dorsal Spinal Surgery in Patients With Cervical Spondylotic Myelopathy鈥擱eply

Zoher Ghogawala, MD; Fred G. Barker II, MD; Edward C. Benzel, MD

Abstract Full Text

JAMA. 2021;326(4):358-359. doi:10.1001/jama.2021.7268

Blinatumomab vs Chemotherapy Among Children With Relapsed Acute Lymphoblastic Leukemia

Motoharu Shibusawa, MD; Keisuke Kidoguchi, MD; Tetsuya Tanimoto, MD

Abstract Full Text

JAMA. 2021;326(4):359. doi:10.1001/jama.2021.8151

Blinatumomab vs Chemotherapy Among Children With Relapsed Acute Lymphoblastic Leukemia鈥擱eply

Franco Locatelli, MD; Gerhard Zugmaier, MD; Arend von Stackelberg, MD

Abstract Full Text

JAMA. 2021;326(4):359-360. doi:10.1001/jama.2021.8154

Correction

Incorrect Figure

Abstract Full Text

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JAMA. 2021;326(4):360. doi:10.1001/jama.2021.9741

November 2024 - July 1883

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July 27, 2021, Vol 326, No. 4, Pages 291-366

COVID-19: Beyond Tomorrow

Women's Health

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