October 5, 2021 Issue of JAMA

October 5, 2021, Vol 326, No. 13, Pages 1233-1338

This Week in JAMA

Audio Highlights

Abstract Full Text

free access online only has audio

JAMA. 2021;326(13):e2018157. doi:10.1001/jama.2020.18157

Podcast: Scopolamine Butylbromide for End-of-Life Death Rattle, Pulmonary Embolism Workups in COPD Exacerbation, Eosinophilic Esophagitis review, and more

Original Investigation

Caring for the Critically Ill Patient

Effect of Prophylactic Subcutaneous Scopolamine Butylbromide on Death Rattle in Patients at the End of Life: The SILENCE Randomized Clinical Trial

Harriëtte J. van Esch, MD; Lia van Zuylen, MD, PhD; Eric C. T. Geijteman, MD, PhD; et al.

Abstract Full Text

free access has audio

JAMA. 2021;326(13):1268-1276. doi:10.1001/jama.2021.14785

This randomized clinical trial investigated whether prophylactic scopolamine butylbromide could reduce the death rattle among patients near the end of life.

Podcast: Scopolamine Butylbromide for Preventing End-of-Life Death Rattle

Editorial
Preventing Death Rattle With Prophylactic Subcutaneous Scopolamine Butylbromide
Jared R. Lowe, MD; Laura C. Hanson, MD, MPH

JAMA
- Podcast: Scopolamine Butylbromide for Preventing End-of-Life Death Rattle

Effect of a Pulmonary Embolism Diagnostic Strategy on Clinical Outcomes in Patients Hospitalized for COPD Exacerbation: A Randomized Clinical Trial

David Jiménez, MD, PhD; Alvar Agustí, MD, PhD; Eva Tabernero, MD; et al.

Abstract Full Text

free access

JAMA. 2021;326(13):1277-1285. doi:10.1001/jama.2021.14846

This randomized clinical trial examines the effect of an active strategy for the diagnosis of pulmonary embolism in addition to usual care on clinical outcomes, including nonfatal symptomatic venous thromboembolism, readmission for chronic obstructive pulmonary disorder (COPD), or death within 90 days after randomization, among individuals hospitalized for an exacerbation of COPD.

Trends in Cardiovascular Risk Factors in US Adults by Race and Ethnicity and Socioeconomic Status, 1999-2018

Jiang He, MD, PhD; Zhengbao Zhu, MD, PhD; Joshua D. Bundy, PhD, MPH; et al.

Abstract Full Text

free access

JAMA. 2021;326(13):1286-1298. doi:10.1001/jama.2021.15187

This National Health and Nutrition Examination Survey study assesses US trends in cardiovascular risk factors by race and ethnicity and by socioeconomic status from 1999 to 2018.

US Emergency Department Visits Attributed to Medication Harms, 2017-2019

Daniel S. Budnitz, MD, MPH; Nadine Shehab, PharmD, MPH; Maribeth C. Lovegrove, MPH; et al.

Abstract Full Text

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JAMA. 2021;326(13):1299-1309. doi:10.1001/jama.2021.13844

This surveillance study describes the characteristics of emergency department visits for acute harms from both therapeutic and nontherapeutic medication use in the US.

Research Letter

Mask-Wearing Behavior at the 2021 NCAA Men鈥檚 Basketball Tournament

Joshua R. Vest, PhD, MPH; Justin Blackburn, PhD; Shama Cash-Goldwasser, MD, MPH; et al.

Abstract Full Text

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JAMA. 2021;326(13):1324-1325. doi:10.1001/jama.2021.14057

This cross-sectional study examines the mask-wearing behavior of attendees at the 2021 NCAA men鈥檚 basketball tournament in an attempt to help other venues prepare for future events during the pandemic.

Physician Practice Interruptions in the Treatment of Medicare Patients During the COVID-19 Pandemic

Hannah T. Neprash, PhD; Michael E. Chernew, PhD

Abstract Full Text

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JAMA. 2021;326(13):1325-1328. doi:10.1001/jama.2021.16324

This study uses Medicare data to assess physician practice interruptions during the 2019-2020 period of the COVID-19 pandemic and provides preliminary evidence on whether those interruptions suggest early retirements or exit from medical practice.

Viewpoint

Strengthening Global Health Security and Reforming the International Health Regulations: Making the World Safer From Future Pandemics

Antony J. Blinken, JD; Xavier Becerra, JD

Abstract Full Text

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JAMA. 2021;326(13):1255-1256. doi:10.1001/jama.2021.15611

This Viewpoint from the US Secretary of State and the US Secretary of Health and Human Services outlines how the US government, in partnership with other nations and organizations such as the WHO, should work to establish a more effective, innovative, responsive, and equitable system for global health security.

An International Agreement on Pandemic Prevention and Preparedness

Lawrence O. Gostin, JD; Sam F. Halabi, JD, MPhil; Kevin A. Klock, JD

Abstract Full Text

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JAMA. 2021;326(13):1257-1258. doi:10.1001/jama.2021.16104

This Viewpoint discusses international efforts to address the COVID-19 and future pandemics as well as offers steps that the international community can take to fix gaps in pandemic response.

Holding Hope for Patients With Serious Illness

Abby Rosenberg, MD, MS, MA; Robert M Arnold, MD; Yael Schenker, MD, MAS

Abstract Full Text

JAMA. 2021;326(13):1259-1260. doi:10.1001/jama.2021.14802

This Viewpoint explains the complex emotion of hope and provides guidance to clinicians for supportively conversing about hope with seriously ill patients.

A Piece of My Mind

Good Enough for Whom?

Sharon Reece, MD

Abstract Full Text

JAMA. 2021;326(13):1261-1262. doi:10.1001/jama.2021.16032

In this narrative medicine essay, a family physician shares her doubts about her positive effect while serving Canadian Indigenous patients but realizes and appreciates the lasting impact her patients had on her.

Editorial

Preventing Death Rattle With Prophylactic Subcutaneous Scopolamine Butylbromide

Jared R. Lowe, MD; Laura C. Hanson, MD, MPH

Abstract Full Text

has audio

JAMA. 2021;326(13):1263-1265. doi:10.1001/jama.2021.9846

Podcast: Scopolamine Butylbromide for Preventing End-of-Life Death Rattle

Ninth International Congress on Peer Review and Scientific Publication: Call for Abstracts

John P. A. Ioannidis, MD, DSc; Michael Berkwits, MD, MSCE; Annette Flanagin, RN, MA; et al.

Abstract Full Text

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JAMA. 2021;326(13):1265-1267. doi:10.1001/jama.2021.16596

Editorial
Three Decades of Peer Review Congresses
Drummond Rennie, MD; Annette Flanagin, RN, MA

JAMA

Review

Eosinophilic Esophagitis: A Review

Amanda Muir, MD, MSTR; Gary W. Falk, MD, MS

Abstract Full Text

JAMA. 2021;326(13):1310-1318. doi:10.1001/jama.2021.14920

This review summarizes current evidence regarding the diagnosis of eosinophilic esophagitis, a chronic immune-mediated inflammatory disease of the esophagus, and treatment approaches, including pharmacologic interventions, dietary therapy, and endoscopic dilation.

JAMA Insights

Infectious Keratitis in 2021

Marlene L. Durand, MD; Miriam Baron Barshak, MD; James Chodosh, MD, MPH

Abstract Full Text

JAMA. 2021;326(13):1319-1320. doi:10.1001/jama.2021.0424

This JAMA Insights summarizes the prevalence of keratitis and its association with improper use of contact lenses; and summarizes the types, pathology, diagnosis, and treatment of keratitis.

JAMA Clinical Guidelines Synopsis

Inferior Vena Cava Filters for the Treatment of Patients With Venous Thromboembolic Disease

Osman Ahmed, MD; Adam S. Cifu, MD; Jonathan Paul, MD

Abstract Full Text

JAMA. 2021;326(13):1321-1322. doi:10.1001/jama.2021.9262

This JAMA Clinical Guidelines Synopsis summarizes the clinical practice guideline from the Society of Interventional Radiology regarding use of inferior vena cava filters for patients with venous thromboembolic disease.

Medical News & Perspectives

How COVID-19 Made It Even Tougher to Know ICU Patients as Individuals

Rita Rubin, MA

Abstract Full Text

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JAMA. 2021;326(13):1241-1243. doi:10.1001/jama.2021.13462

This Medical News feature discusses with Vanderbilt University critical care specialist E. Wesley Ely, MD, MPH, the COVID-19 pandemic鈥檚 impact on progress that had been made in intensive care units.

Podcast: Rebounding From COVID-19鈥檚 Reversal of Recent Progress in the ICU
Podcast: September 2021 Medical News Summary

Quick Uptakes

Choose ARBs Over ACE Inhibitors for First-line Hypertension Treatment, Large New Analysis Suggests

Jennifer Abbasi

Abstract Full Text

JAMA. 2021;326(13):1244-1245. doi:10.1001/jama.2021.14017

This Medical News article discusses a head-to-head comparison of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for high blood pressure treatment.

News From the 糖心vlog

Pediatric Depression and Anxiety Doubled During the Pandemic

Anita Slomski

Abstract Full Text

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JAMA. 2021;326(13):1246. doi:10.1001/jama.2021.16374

Cycling May Lower Mortality Risk in People Who Have Diabetes

Anita Slomski

Abstract Full Text

JAMA. 2021;326(13):1246. doi:10.1001/jama.2021.15425

Oral Upadacitinib Beats Subcutaneous Dupilumab for Atopic Dermatitis

Anita Slomski

Abstract Full Text

JAMA. 2021;326(13):1246. doi:10.1001/jama.2021.16375

Study Projects Lifetime Benefits of Dapagliflozin in HFrEF

Anita Slomski

Abstract Full Text

JAMA. 2021;326(13):1246. doi:10.1001/jama.2021.16376

News From the Food and Drug Administration

Mandated Education for Opioid Prescribers Is Up for Discussion

Rebecca Voelker, MSJ

Abstract Full Text

JAMA. 2021;326(13):1247. doi:10.1001/jama.2021.16443

A First in Stroke Rehabilitation

Rebecca Voelker, MS

Abstract Full Text

JAMA. 2021;326(13):1247. doi:10.1001/jama.2021.16089

FDA Reaches a Milestone in Generic Drug Approvals

Rebecca Voelker, MSJ

Abstract Full Text

JAMA. 2021;326(13):1247. doi:10.1001/jama.2021.16444

The Arts and Medicine

Japanese Medical Mnemonics鈥擫anguage, Reflection, and Art

Nick Love, MD, PhD; Yuichi J. Shimada, MD, MPH

Abstract Full Text

JAMA. 2021;326(13):1238-1240. doi:10.1001/jama.2021.6972

This Arts and Medicine feature explains how Japanese language medical mnemonics are constructed and features a 16-panel mixed-media art installation featuring elements of mnemonics for vaccines, relative bradycardia, and subclavian artery anatomy.

Poetry and Medicine

Every Time

Alex Ruuska, BA, BS

Abstract Full Text

JAMA. 2021;326(13):1333. doi:10.1001/jama.2021.11547

JAMA Revisited

Modern Problems in Two Medical Specialties

Abstract Full Text

JAMA. 2021;326(13):1334. doi:10.1001/jama.2020.18158

JAMA Patient Page

Intermittent Fasting

Zhaoping Li, MD, PhD; David Heber, MD, PhD

Abstract Full Text

free access

JAMA. 2021;326(13):1338. doi:10.1001/jama.2020.15140

This JAMA Patient Page explains intermittent fasting (intervals of limiting food intake for extended periods) and its potential weight-loss benefits, risks, and side effects.

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