July 11, 2017 Issue of JAMA

July 11, 2017, Vol 318, No. 2, Pages 105-210

This Week in JAMA

Highlights

Abstract Full Text

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JAMA. 2017;318(2):105-107. doi:10.1001/jama.2016.13212

Podcast: Managing antidepressants in treatment-refractory depression, CPAP and CVD in OSA, behavioral counseling to promote healthy lifestyle, and more

Original Investigation

Effect of Antidepressant Switching vs Augmentation on Remission Among Patients With Major Depressive Disorder Unresponsive to Antidepressant Treatment: The VAST-D Randomized Clinical Trial

Somaia Mohamed, MD, PhD; Gary R. Johnson, MS; Peijun Chen, MD, PhD, MPH; et al.

Abstract Full Text

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JAMA. 2017;318(2):132-145. doi:10.1001/jama.2017.8036

This randomized clinical trial compares the effects on symptom remission of switching to bupropion, adding bupropion, or adding aripiprazole to baseline treatment among Veterans Affairs patients with antidepressant-resistant major depressive disorder.

Editorial
Lessons Learned From the VA Augmentation and Switching Treatments for Improving Depression Outcomes (VAST-D) Study
Maurizio Fava, MD

JAMA

Association Between Alendronate Use and Hip Fracture Risk in Older Patients Using Oral Prednisolone

Kristian F. Axelsson, MD, MSc; Anna G. Nilsson, MD, PhD; Hans Wedel, PhD; et al.

Abstract Full Text

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JAMA. 2017;318(2):146-155. doi:10.1001/jama.2017.8040

This Swedish cohort study investigates whether treatment with alendronate is associated with reduced risk of hip fracture among older patients using oral glucocorticoids.

Association of Positive Airway Pressure With Cardiovascular Events and Death in Adults With Sleep Apnea: A Systematic Review and Meta-analysis

Jie Yu, MD; Zien Zhou, MD; R. Doug McEvoy, MD; et al.

Abstract Full Text

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JAMA. 2017;318(2):156-166. doi:10.1001/jama.2017.7967

This systematic review analyzes 10 randomized clinical trials comparing the effects of positive airway pressure (PAP) vs sham PAP in reducing cardiovascular outcomes or death among patients with sleep apnea.

Editorial
Does Obstructive Sleep Apnea Treatment Reduce Cardiovascular Risk?It Is Far Too Soon to Say
Daniel J. Gottlieb, MD, MPH

JAMA

Research Letter

Overall Survival Results of a Trial Assessing Patient-Reported Outcomes for Symptom Monitoring During Routine Cancer Treatment

Ethan Basch, MD, MSc; Allison M. Deal, MS; Amylou C. Dueck, PhD; et al.

Abstract Full Text

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JAMA. 2017;318(2):197-198. doi:10.1001/jama.2017.7156

This study assesses overall survival associated with electronic patient-reported symptom monitoring vs usual care during routine cancer treatment.

US Preventive Services Task Force

Recommendation Statement

Behavioral Counseling to Promote a Healthful Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Cardiovascular Risk Factors: US Preventive Services Task Force Recommendation Statement

US Preventive Services Task Force

Abstract Full Text

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JAMA. 2017;318(2):167-174. doi:10.1001/jama.2017.7171

This Recommendation Statement from the US Preventive Services Task Force recommends that primary care professionals individualize the decision to refer adults without obesity and cardiovascular risk factors to behavioral counseling to promote healthful diet and physical activity (C recommendation).

Podcast: USPSTF Recommendation: Behavioral Counseling for CVD Prevention

Editorial
Cardiovascular Risk Factor Control for All
Philip Greenland, MD; Valentin Fuster, MD, PhD

JAMA
Healthful Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Known Risk Factors: Is Behavioral Counselling Necessary?
Simon Capewell, MD, DSc; Christopher Dowrick, MD, FRCGP

JAMA Intern Med
Healthful Physical Activity and Diet Promotion鈥擣or the Many or the Few?
Bonnie Spring, PhD

JAMA Cardiol

Evidence Report

Behavioral Counseling to Promote a Healthful Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Known Cardiovascular Disease Risk Factors: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Carrie D. Patnode, PhD; Corrine V. Evans, MPP; Caitlyn A. Senger, MPH; et al.

Abstract Full Text

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JAMA. 2017;318(2):175-193. doi:10.1001/jama.2017.3303

This Evidence Report and systematic review to support a 2017 US Preventive Services Task Force Recommendation Statement summarizes current evidence on benefits and harms of behavioral counseling for primary prevention of cardiovascular disease (CVD) in adults without known CVD risk factors.

Editorial
Cardiovascular Risk Factor Control for All
Philip Greenland, MD; Valentin Fuster, MD, PhD

JAMA
Healthful Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Known Risk Factors: Is Behavioral Counselling Necessary?
Simon Capewell, MD, DSc; Christopher Dowrick, MD, FRCGP

JAMA Intern Med
Healthful Physical Activity and Diet Promotion鈥擣or the Many or the Few?
Bonnie Spring, PhD

JAMA Cardiol

Viewpoint

Reducing Excessive Use of Antipsychotic Agents in Nursing Homes

Jerry H. Gurwitz, MD; Alice Bonner, PhD, RN; Donald M. Berwick, MD, MPP

Abstract Full Text

JAMA. 2017;318(2):118-119. doi:10.1001/jama.2017.7032

This Viewpoint describes the structure and outcomes of a national initiative of the Centers for Medicare & Medicaid Services to reduce the use of antipsychotics in nursing homes.

Antiplatelet Therapy in Patients With Coronary Stents Undergoing Elective Noncardiac Surgery: Continue, Stop, or Something in Between?

Christopher P. Childers, MD; Melinda Maggard-Gibbons, MD, MSHS; Paul G. Shekelle, MD, PhD

Abstract Full Text

JAMA. 2017;318(2):120-121. doi:10.1001/jama.2017.7845

This Viewpoint discusses the management of antiplatelet therapy in patients with coronary stents undergoing elective noncardiac surgery.

Social Mission in Health Professions Education: Beyond Flexner

Fitzhugh Mullan, MD

Abstract Full Text

JAMA. 2017;318(2):122-123. doi:10.1001/jama.2017.7286

This Viewpoint urges all medical and health professional training programs to make social mission a central curricular focus to help evenly distribute health care and to eliminate health disparities among patients who have little means and access to health care.

A Piece of My Mind

Stories Doctors Tell

Tracy Moniz, PhD; Lorelei Lingard, PhD; Chris Watling, MD, PhD

Abstract Full Text

JAMA. 2017;318(2):124-125. doi:10.1001/jama.2017.5518

Editorial

Lessons Learned From the VA Augmentation and Switching Treatments for Improving Depression Outcomes (VAST-D) Study

Maurizio Fava, MD

Abstract Full Text

JAMA. 2017;318(2):126-128. doi:10.1001/jama.2017.8030

Does Obstructive Sleep Apnea Treatment Reduce Cardiovascular Risk?It Is Far Too Soon to Say

Daniel J. Gottlieb, MD, MPH

Abstract Full Text

JAMA. 2017;318(2):128-130. doi:10.1001/jama.2017.7966

Cardiovascular Risk Factor Control for All

Philip Greenland, MD; Valentin Fuster, MD, PhD

Abstract Full Text

JAMA. 2017;318(2):130-131. doi:10.1001/jama.2017.7648

From the 糖心vlog

Balancing Ischemic and Bleeding Risks of Prolonged Dual Antiplatelet Therapy

Glenn N. Levine, MD

Abstract Full Text

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JAMA. 2017;318(2):194-195. doi:10.1001/jama.2017.6698

This commentary discusses a study published in JAMA Cardiology that assessed the prognosis of cardiovascular and bleeding events associated with dual antiplatelet therapy continued beyond a year after coronary stenting.

Podcast: Dual Antiplatelet Therapy: Balancing Ischemic and Bleeding Risk

Medical News & Perspectives

Starch-Based 鈥淪uper Food鈥� May Protect Against Variety of Diseases

Rita Rubin, MA

Abstract Full Text

JAMA. 2017;318(2):112-114. doi:10.1001/jama.2017.5966

This Medical News article discusses research exploring the clinical potential of a chemically modified dietary starch to protect against type 1 diabetes and other diseases.

The JAMA Forum