February 28, 2017 Issue of JAMA

February 28, 2017, Vol 317, No. 8, Pages 783-880

This Week in JAMA

Highlights

Abstract Full Text

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JAMA. 2017;317(8):783-785. doi:10.1001/jama.2016.13009

Podcast: Trends in secondary cancers after childhood cancer treatment, comparison of type 1 vs type 2 diabetes complications in childhood and adolescence, overuse of services as an adverse event, and more

Original Investigation

Temporal Trends in Treatment and Subsequent Neoplasm Risk Among 5-Year Survivors of Childhood Cancer, 1970-2015

Lucie M. Turcotte, MD, MPH, MS; Qi Liu, MS; Yutaka Yasui, PhD; et al.

Abstract Full Text

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JAMA. 2017;317(8):814-824. doi:10.1001/jama.2017.0693

This cohort study assesses the association between radiation and chemotherapy dose changes over time and risk of subsequent neoplasms among 5-year survivors of childhood cancer diagnosed between 1970 and 1990.

Association of Type 1 Diabetes vs Type 2 Diabetes Diagnosed During Childhood and Adolescence With Complications During Teenage Years and Young Adulthood

Dana Dabelea, MD, PhD; Jeanette M. Stafford, MS; Elizabeth J. Mayer-Davis, PhD; et al.

Abstract Full Text

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JAMA. 2017;317(8):825-835. doi:10.1001/jama.2017.0686

This cohort study uses diabetes registry data to compare rates of complications related to type 1 vs type 2 diabetes among teenagers and young adults diagnosed with diabetes during childhood and adolescence.

Association of Antithrombotic Drug Use With Subdural Hematoma Risk

David Gaist, MD, PhD; Luis Alberto García Rodríguez, MD; Maja Hellfritzsch, MD; et al.

Abstract Full Text

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JAMA. 2017;317(8):836-846. doi:10.1001/jama.2017.0639

This case-control study uses Danish national registry data to estimate associations between antiplatelet and antithrombotic drug use and incident subdural hematoma.

Video: Association of Antithrombotic Drug Use With Subdural Hematoma Risk

Research Letter

Difference Between Estimated Purchase Price and Insurance Payments for Knee and Hip Implants in Privately Insured Patients Younger Than 65 Years

Yi-Ju Tseng, PhD; Kenneth D. Mandl, MD, MPH

Abstract Full Text

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JAMA. 2017;317(8):854-855. doi:10.1001/jama.2016.19579

This study uses claims data to compare insurance payments for knee and hip implants to the estimated price at which the hospital purchased the implant.

Viewpoint

Step Therapy鈥擟linical Algorithms, Legislation, and Optimal Prescribing

Michael A. Fischer, MD, MS; Jerry Avorn, MD

Abstract Full Text

JAMA. 2017;317(8):801-802. doi:10.1001/jama.2016.20619

This Viewpoint discusses step therapy as a means of controlling prescription drug costs, different categories of step therapy, and the challenges of using this approach to ensure quality and affordability of prescribing.

Linking Immunization Status and Eligibility for Welfare and Benefits Payments: The Australian 鈥淣o Jab, No Pay鈥� Legislation

Y. Tony Yang, ScD, LLM, MPH; David M. Studdert, LLB, ScD, MPH

Abstract Full Text

JAMA. 2017;317(8):803-804. doi:10.1001/jama.2017.0123

The Viewpoint describes Australia鈥檚鈥淣o Jab, No Pay鈥� immunization program that links adherence to vaccination with welfare payment benefits and describes prospects for adoption of such a public policy in the United States.

Better Evidence to Guide Payment Reforms: Recognizing the Importance of Perspective

William H. Shrank, MD, MSHS; Robert S. Saunders, PhD; Mark McClellan, MD, PhD

Abstract Full Text

JAMA. 2017;317(8):805-806. doi:10.1001/jama.2017.0034

This Viewpoint discusses the importance of accounting for academic, business, government, and payer perspectives on evidence when formulating health care payment reforms, and of adaptive methods that allow stakeholders to make changes based on experience with reform implementation.

Surviving Sepsis Guidelines: A Continuous Move Toward Better Care of Patients With Sepsis

Daniel De Backer, MD; Todd Dorman, MD, PhD

Abstract Full Text

JAMA. 2017;317(8):807-808. doi:10.1001/jama.2017.0059

This Viewpoint describes the history of the Surviving Sepsis Campaign (SSC), the rationale for and results of the January 2017 fourth revision to the Surviving Sepsis Guidelines, and future directions for the SSC.

A Piece of My Mind

Eradicating a Genetic Mutation

Maryl Goldberg Sackeim, MD

Abstract Full Text

JAMA. 2017;317(8):809. doi:10.1001/jama.2016.15136

Editorial

Reducing Overuse鈥擨s Patient Safety the Answer?

Allison Lipitz-Snyderman, PhD; Deborah Korenstein, MD

Abstract Full Text

JAMA. 2017;317(8):810-811. doi:10.1001/jama.2017.0896

Thank You to JAMA Authors, Peer Reviewers, and Readers

Phil B. Fontanarosa, MD; Howard Bauchner, MD; Robert M. Golub, MD

Abstract Full Text

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JAMA. 2017;317(8):812-813. doi:10.1001/jama.2017.1168

JAMA Professionalism

Is Excessive Resource Utilization an Adverse Event?

Josué A. Zapata, MD, MBA; Andrew R. Lai, MD, MPH; Christopher Moriates, MD

Abstract Full Text

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JAMA. 2017;317(8):849-850. doi:10.1001/jama.2017.0698

This JAMA Professionalism article uses the case of a patient with advanced illness who underwent extensive testing and procedures to discuss overuse of health care resources as a patient safety issue.

Podcast: Treating Resource Overutilization Like a Complication

Editorial
Reducing Overuse鈥擨s Patient Safety the Answer?
Allison Lipitz-Snyderman, PhD; Deborah Korenstein, MD

JAMA

JAMA Clinical Guidelines Synopsis

Management of Sepsis and Septic Shock

Michael D. Howell, MD, MPH; Andrew M. Davis, MD, MPH

Abstract Full Text

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JAMA. 2017;317(8):847-848. doi:10.1001/jama.2017.0131

This JAMA Clinical Guidelines Synopsis summarizes the Surviving Sepsis Campaign鈥檚, Society of Critical Care Medicine鈥檚, and European Society of Intensive Care Medicine鈥檚 2017 guideline on management of sepsis and septic shock.

Video: Video 1. Surviving Sepsis Campaign International Guidelines for Management of Sepsis and Septic Shock: 2016 Guideline Development Process
Video: Video 2. Surviving Sepsis Campaign International Guidelines for Management of Sepsis and Septic Shock: 2016 Recommendations for Initial Resuscitation
Video: Video 3. Surviving Sepsis Campaign International Guidelines for Management of Sepsis and Septic Shock: 2016 Management Recommendations and Differences From 2012 Guideline
Video: Video 4. Surviving Sepsis Campaign International Guidelines for Management of Sepsis and Septic Shock: Questions About 2016 Management Recommendations

Podcast: Why the New Sepsis Guideline Changed
Podcast: Updated Guidelines for Sepsis Management

JAMA Clinical Challenge

A 55-Year-Old Man With a Painful Rash on the Sole of His Foot

Ramya Vangipuram, MD; Stephen K. Tyring, MD, PhD

Abstract Full Text

JAMA. 2017;317(8):851-852. doi:10.1001/jama.2016.20894

A 55-year-old man presented with 2- to 3-mm grouped vesicles on an erythematous base in a discrete area on the sole of his foot. He reported no fevers, chills, or malaise and denied history of human immunodeficiency virus, hepatitis, chickenpox, or recurrent infections. What would you do next?

Medical News & Perspectives

Amid Reports of Infant Deaths, FTC Cracks Down on Homeopathy While FDA Investigates

Jennifer Abbasi

Abstract Full Text

JAMA. 2017;317(8):793-795. doi:10.1001/jama.2016.19090

This Medical News article discusses adverse event reports about homeopathic teething products.

The JAMA Forum

What Might an ACA Replacement Plan Look Like?

Larry Levitt, MPP

Abstract Full Text

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JAMA. 2017;317(8):795-796. doi:10.1001/jama.2017.0661

News From the Centers for Disease Control and Prevention

Hospital Costs for Birth Defects Reach Tens of Billions

Abstract Full Text

JAMA. 2017;317(8):799. doi:10.1001/jama.2017.0551

Youths Recognize Costs of Smoking

Abstract Full Text

JAMA. 2017;317(8):799. doi:10.1001/jama.2017.0723

Clinical Trials Update

Crizanlizumab Prevents Sickle Cell Pain Crises

Anita Slomski, MA

Abstract Full Text

JAMA. 2017;317(8):798. doi:10.1001/jama.2017.0355

Listerine May Help Control Spread of Gonorrhea

Anita Slomski, MA

Abstract Full Text

JAMA. 2017;317(8):798. doi:10.1001/jama.2017.1130

Improving Shared Decision Making in Management of Dementia

Anita Slomski, MA

Abstract Full Text

JAMA. 2017;317(8):798. doi:10.1001/jama.2017.1135

Health Agencies Update

For Health Disparities, Don鈥檛 Ignore the Microbiome

Jennifer Abbasi

Abstract Full Text

JAMA. 2017;317(8):797. doi:10.1001/jama.2017.0447

VHA Initiative Reduces Risky Opioid Prescribing

Jennifer Abbasi

Abstract Full Text

JAMA. 2017;317(8):797. doi:10.1001/jama.2017.1087

Public-Private Partnership Speeds Investigator Access to Cancer Drugs

Jennifer Abbasi

Abstract Full Text

JAMA. 2017;317(8):797. doi:10.1001/jama.2017.1089

The Arts and Medicine

搁别尘产谤补苍诲迟鈥檚 Senses: Lessons in 鈥淧erceiving鈥� the Patient

Christopher C. Muth, MD

Abstract Full Text

JAMA. 2017;317(8):790-792. doi:10.1001/jama.2017.0553

This Arts and Medicine essay discusses the recent discovery of one in a series of Rembrandt paintings featuring physicians and patients, and the lessons the images hold for the contemporary practice of medicine.

Poetry and Medicine