September 19, 2017 Issue of JAMA

September 19, 2017, Vol 318, No. 11, Pages 979-1080

This Week in JAMA

Highlights

Abstract Full Text

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JAMA. 2017;318(11):979-981. doi:10.1001/jama.2016.13311

Podcast: BP control in low income settings, antibiotics after c-section, trends in carotid artery interventions, and more

Original Investigation

Effect of a Community Health Worker鈥揕ed Multicomponent Intervention on Blood Pressure Control in Low-Income Patients in Argentina: A Randomized Clinical Trial

Jiang He, MD, PhD; Vilma Irazola, MD, PhD; Katherine T. Mills, PhD; et al.

Abstract Full Text

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JAMA. 2017;318(11):1016-1025. doi:10.1001/jama.2017.11358

This cluster randomized trial compares the effects on blood pressure control of a community health worker鈥搇ed home intervention vs physician education vs patient text messaging among low-income patients with hypertension in Argentina.

Editorial
Improving Blood Pressure Control and Health Systems With Community Health Workers
Mark D. Huffman, MD, MPH; Dike Ojji, MD, PhD; Donald M. Lloyd-Jones, MD, ScM

JAMA

Effect of Post鈥揅esarean Delivery Oral Cephalexin and Metronidazole on Surgical Site Infection Among Obese Women: A Randomized Clinical Trial

Amy M. Valent, DO; Chris DeArmond, RN; Judy M. Houston, RPh; et al.

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JAMA. 2017;318(11):1026-1034. doi:10.1001/jama.2017.10567

This randomized trial compares the effects of postoperative oral cephalexin-metronidazole vs placebo on frequency of surgical site infection (SSI) in obese women undergoing cesarean delivery.

Editorial
Postoperative Antimicrobial Prophylaxis Following Cesarean Delivery in Obese Women: An Exception to the Rule?
David P. Calfee, MD, MS; Amos Grünebaum, MD

JAMA

Carotid Endarterectomy and Carotid Artery Stenting in the US Medicare Population, 1999-2014

Judith H. Lichtman, PhD; Michael R. Jones, MD; Erica C. Leifheit, PhD; et al.

Abstract Full Text

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JAMA. 2017;318(11):1035-1046. doi:10.1001/jama.2017.12882

This population epidemiology study uses Medicare administrative data to describe national trends in performance and outcomes of carotid endarterectomy and carotid artery stenting from 1999 to 2014 among fee-for-service Medicare beneficiaries aged 65 years or older.

Preliminary Communication

Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial

David Hui, MD, MSc; Susan Frisbee-Hume, MS; Annie Wilson, MSN; et al.

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JAMA. 2017;318(11):1047-1056. doi:10.1001/jama.2017.11468

This randomized clinical trial compares the effect of lorazepam vs placebo added to haloperidol for persistent agitation in patients with advanced cancer and delirium.

Editorial
Humanizing the Treatment of Hyperactive Delirium in the Last Days of Life
Pratik P. Pandharipande, MD, MSCI; E. Wesley Ely, MD, MPH

JAMA

Research Letter

Contribution of Opioid-Involved Poisoning to the Change in Life Expectancy in the United States, 2000-2015

Deborah Dowell, MD, MPH; Elizabeth Arias, PhD; Kenneth Kochanek, MA; et al.

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JAMA. 2017;318(11):1065-1067. doi:10.1001/jama.2017.9308

This study uses US National Vital Statistics mortality data to assess change in US life expectancy from 2000 to 2015 attributable to opioid-involved poisonings.

Viewpoint

Nonvoluntary Psychiatric Treatment Is Distinct From Involuntary Psychiatric Treatment

Dominic A. Sisti, PhD

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JAMA. 2017;318(11):999-1000. doi:10.1001/jama.2017.10318

This Viewpoint discusses the differences between voluntary, involuntary, and nonvoluntary psychiatric treatment.

The United Kingdom Sets Limits on Experimental Treatments: The Case of Charlie Gard

Robert D. Truog, MD

Abstract Full Text

JAMA. 2017;318(11):1001-1002. doi:10.1001/jama.2017.10410

This Viewpoint discusses the case of Charlie Gard, a young boy with severe mitochondrial disease on life support in the United Kingdom, and the issues at stake in the conflict between his parents鈥� wishes to pursue expensive, unproven treatment and the UK National Health Service鈥檚 insistence on a palliative approach.

Drug Development at the Portfolio Level Is Important for Policy, Care Decisions and Human Protections

Jonathan Kimmelman, PhD; Benjamin Carlisle, MA; Mithat Gönen, PhD

Abstract Full Text

JAMA. 2017;318(11):1003-1004. doi:10.1001/jama.2017.11502

This Viewpoint discusses the drug development portfolio鈥攁 family of trials assessing a drug for different indications or in different combinations with other drugs鈥攁nd summarizes some of the challenges drug portfolios pose for policy, care, and human protections.

A Piece of My Mind

The Lower Seven-Eighths

Joseph Gascho, MD

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JAMA. 2017;318(11):1005-1006. doi:10.1001/jama.2017.7751

鈥淭he Tunnel at the End of the Light鈥�: Preparing to Attend on the Inpatient Medical Wards

Vineet Chopra, MD, MSc; Sanjay Saint, MD, MPH

Abstract Full Text

JAMA. 2017;318(11):1007-1008. doi:10.1001/jama.2017.8324

Editorial

Improving Blood Pressure Control and Health Systems With Community Health Workers

Mark D. Huffman, MD, MPH; Dike Ojji, MD, PhD; Donald M. Lloyd-Jones, MD, ScM

Abstract Full Text

JAMA. 2017;318(11):1009-1011. doi:10.1001/jama.2017.11464

Postoperative Antimicrobial Prophylaxis Following Cesarean Delivery in Obese Women: An Exception to the Rule?

David P. Calfee, MD, MS; Amos Grünebaum, MD

Abstract Full Text

JAMA. 2017;318(11):1012-1013. doi:10.1001/jama.2017.10535

Humanizing the Treatment of Hyperactive Delirium in the Last Days of Life

Pratik P. Pandharipande, MD, MSCI; E. Wesley Ely, MD, MPH

Abstract Full Text

JAMA. 2017;318(11):1014-1015. doi:10.1001/jama.2017.11466

JAMA Clinical Guidelines Synopsis

Antipsychotics to Treat Agitation or Psychosis in Patients With Dementia

Daniel Yohanna, MD; Adam S. Cifu, MD

Abstract Full Text

JAMA. 2017;318(11):1057-1058. doi:10.1001/jama.2017.11112

This JAMA Clinical Guidelines Synopsis summarizes the 2016 American Psychiatric Association practice guideline on the use of antipsychotics to treat agitation or psychosis in patients with dementia.

JAMA Clinical Challenge

A Pink Nodule on a Boy's Left Cheek

Wei Liu, MD; Jia-Wei Liu, MD; Dong-Lai Ma, MD, PhD

Abstract Full Text

JAMA. 2017;318(11):1059-1060. doi:10.1001/jama.2017.13023

A 4-year-old boy had a 1-cm well-circumscribed, symmetrical, pinkish, dome-shaped nodule with central erosions on the left cheek. Hair, nails, and mucosae were of normal appearance, and the remainder of the examination was unremarkable. What would you do next?

JAMA Diagnostic Test Interpretation

Urine Drug Screens to Monitor Opioid Use for Managing Chronic Pain

Shannon Haymond, PhD; Geeta Nagpal, MD; Heather Heiman, MD

Abstract Full Text

JAMA. 2017;318(11):1061-1062. doi:10.1001/jama.2017.10593

A 53-year-old woman with chronic low back pain presented for a prescription refill of hydrocodone/acetaminophen. She had partial paralysis from a thoracic spinal cord infarction secondary to aortic dissection from prior cocaine use and reported taking hydrocodone on that day but no recent illicit drug use. Urine immunoassay drug screen results were negative overall but positive for cocaine. How would you proceed?

Medical News & Perspectives

Medical Students Fall Short on Blood Pressure Check Challenge

Jennifer Abbasi

Abstract Full Text

JAMA. 2017;318(11):991-992. doi:10.1001/jama.2017.11255

This Medical News article discusses the importance of correctly prepping patients for blood pressure measurement.

News From the Food and Drug Administration

Relief for Graft-vs-Host Disease

Rebecca Voelker, MSJ

Abstract Full Text

JAMA. 2017;318(11):996. doi:10.1001/jama.2017.12982

Deaths Reported After Intragastric Balloon Surgery

Rebecca Voelker, MSJ

Abstract Full Text

JAMA. 2017;318(11):996. doi:10.1001/jama.2017.12984

The 8-Week Cure for Hepatitis C

Rebecca Voelker, MSJ

Abstract Full Text

JAMA. 2017;318(11):996. doi:10.1001/jama.2017.12994

The JAMA Forum

Community-Based Prevention and Strategies for the Opioid Crisis

Howard K. Koh, MD, MPH

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JAMA. 2017;318(11):993-994. doi:10.1001/jama.2017.13767

Global Health

Progress Stalls in Improving Vaccine Coverage Rates

M.J. Friedrich

Abstract Full Text

JAMA. 2017;318(11):995. doi:10.1001/jama.2017.11783

Exposure to Lychee Orchard Pesticides Linked to AES Outbreak

M.J. Friedrich

Abstract Full Text

JAMA. 2017;318(11):995. doi:10.1001/jama.2017.13606

Lack of Improvement in Health Care for Afghans With Disabilities

M.J. Friedrich

Abstract Full Text

JAMA. 2017;318(11):995. doi:10.1001/jama.2017.13608

The Arts and Medicine

Holding the Self and the World Together: Robert Lowell, Mania, and Having to Write

Jed Myers, MD

Abstract Full Text

JAMA. 2017;318(11):988-989. doi:10.1001/jama.2017.12823

This Arts and Medicine essay uses Kay Redfield Jamison鈥檚 2016 study of poet Robert Lowell to explore writing as a way of calming disintegrated psyches and proposes that physicians collaborate with patients who have bipolar illness to balance the effects medications have on blunting manic symptoms and creative impulses.

Poetry and Medicine

Beginning and End

Carol Snyder Halberstadt

Abstract Full Text

JAMA. 2017;318(11):1073. doi:10.1001/jama.2017.3104

JAMA Revisited

Every Day Is Fish Day

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JAMA. 2017;318(11):1074. doi:10.1001/jama.2017.10487

JAMA Patient Page

Safely Viewing Solar Eclipses

J. Fernando Arévalo, MD; Jun Kong, MD, PhD; Neil M. Bressler, MD

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JAMA. 2017;318(11):1080. doi:10.1001/jama.2017.9495

Comment & Response

Characteristics of Novel Therapeutics and Postmarket Safety Events

Tetsuya Tanimoto, MD; Jinichi Mori, MD, PhD; Yasuo Oshima, MD, PhD

Abstract Full Text

JAMA. 2017;318(11):1067. doi:10.1001/jama.2017.11513

Characteristics of Novel Therapeutics and Postmarket Safety Events鈥擱eply

Nicholas S. Downing, MD; Nilay D. Shah, PhD; Joseph S. Ross, MD, MHS

Abstract Full Text

JAMA. 2017;318(11):1067-1068. doi:10.1001/jama.2017.11517

Shortage or Surplus of Physicians in the United States

Adeel Ajwad Butt, MD, MS

Abstract Full Text

JAMA. 2017;318(11):1068. doi:10.1001/jama.2017.11498

Shortage or Surplus of Physicians in the United States

Jerry Kruse, MD, MSPH

Abstract Full Text

JAMA. 2017;318(11):1068-1069. doi:10.1001/jama.2017.11505

Shortage or Surplus of Physicians in the United States

Amy W. Farnbach Pearson, PhD; Richard S. Larson, MD, PhD

Abstract Full Text

JAMA. 2017;318(11):1069-1070. doi:10.1001/jama.2017.11509

Low-Dose Desmopressin Nasal Spray and FDA Approval

Seymour Fein, MD; Samuel Herschkowitz, MD

Abstract Full Text

JAMA. 2017;318(11):1070-1071. doi:10.1001/jama.2017.11327

Shortage or Surplus of Physicians in the United States鈥擱eply

Ezekiel J. Emanuel, MD, PhD; Emily Gudbranson, BA

Abstract Full Text

JAMA. 2017;318(11):1070. doi:10.1001/jama.2017.11521

Low-Dose Desmopressin Nasal Spray and FDA Approval鈥擱eply

Michael Fralick, MD; Aaron S. Kesselheim, MD, JD, MPH

Abstract Full Text

JAMA. 2017;318(11):1071-1072. doi:10.1001/jama.2017.11343

Notice of Retraction and Replacement: Favini et al. Comparative Trends in Payment Adjustments Between Safety-Net and Other Hospitals Since the Introduction of the Hospital Readmission Reduction Program and Value-Based Purchasing. JAMA. 2017;317(15):1578-1580.

Nathan Favini, MD; Jason M. Hockenberry, PhD; Matlin Gilman, BA, MDiv; et al.

Abstract Full Text

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JAMA. 2017;318(11):1072. doi:10.1001/jama.2017.7755

Notice of Retraction and Replacement: Favini et al. Comparative Trends in Payment Adjustments Between Safety-Net and Other Hospitals Since the Introduction of the Hospital Readmission Reduction Program and Value-Based Purchasing. JAMA. 2017;317(15):1578-1580.

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September 19, 2017, Vol 318, No. 11, Pages 979-1080

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