February 7, 2017 Issue of JAMA

February 7, 2017, Vol 317, No. 5, Pages 453-546

This Week in JAMA

Highlights

Abstract Full Text

free access has audio

JAMA. 2017;317(5):453-455. doi:10.1001/jama.2016.12976

Podcast: Trial of video laryngoscopy for tracheal intubation, outcomes after intubation during CPR, diagnosis and treatment of pituitary adenoma, and more

Original Investigation

Caring for the Critically Ill Patient

Video Laryngoscopy vs Direct Laryngoscopy on Successful First-Pass Orotracheal Intubation Among ICU Patients: A Randomized Clinical Trial

Jean Baptiste Lascarrou, MD; Julie Boisrame-Helms, MD, PhD; Arthur Bailly, MD; et al.

Abstract Full Text

free access

JAMA. 2017;317(5):483-493. doi:10.1001/jama.2016.20603

This randomized clinical trial compares the effects of video vs direct laryngoscopy on the success of first-pass orotracheal intubation in patients admitted to intensive care units (ICUs) in France.

Editorial
Video Laryngoscopy in the Intensive Care Unit: Seeing Is Believing, But That Does Not Mean It鈥檚 True
Brian O鈥橤ara, MD; Samuel Brown, MD, MS; Daniel Talmor, MD, MPH

JAMA

Caring for the Critically Ill Patient

Association Between Tracheal Intubation During Adult In-Hospital Cardiac Arrest and Survival

Lars W. Andersen, MD, MPH, PhD; Asger Granfeldt, MD, PhD, DMSc; Clifton W. Callaway, MD, PhD; et al.

Abstract Full Text

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JAMA. 2017;317(5):494-506. doi:10.1001/jama.2016.20165

This cohort study uses data from the Get With The Guidelines鈥揜esuscitation registry to investigate the association between tracheal intubation during adult in-hospital cardiac arrest and survival to hospital discharge.

Editorial
Whether to Intubate During Cardiopulmonary Resuscitation: Conventional Wisdom vs Big Data
Derek C. Angus, MD, MPH

JAMA

Association of Sickle Cell Trait With Hemoglobin A_1c in African Americans

Mary E. Lacy, MPH; Gregory A. Wellenius, ScD; Anne E. Sumner, MD; et al.

Abstract Full Text

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JAMA. 2017;317(5):507-515. doi:10.1001/jama.2016.21035

This study of 2 population cohorts of African Americans compares hemoglobin A_1c values among those with vs without sickle cell trait to determine whether the trait interferes with identification of prediabetes or diabetes.

Editorial
Sickle Cell Trait and Interpretation of Hemoglobin A_1c Levels
Anthony J. Bleyer, MD, MS; Joseph A. Aloi, MD

JAMA

Research Letter

Proportion and Cost of Unplanned 30-Day Readmissions After Sepsis Compared With Other Medical Conditions

Florian B. Mayr, MD, MPH; Victor B. Talisa, MS; Vikram Balakumar, MD; et al.

Abstract Full Text

free access

JAMA. 2017;317(5):530-531. doi:10.1001/jama.2016.20468

This study uses data from a US readmissions database to assess whether sepsis hospitalizations account for a higher proportion of unplanned 30-day readmissions than hospitalizations for acute myocardial infarction, heart failure, chronic obstructive pulmonary disease, and pneumonia.

Genetic Testing and Counseling Among Patients With Newly Diagnosed Breast Cancer

Allison W. Kurian, MD, MSc; Kent A. Griffith, MS; Ann S. Hamilton, PhD; et al.

Abstract Full Text

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JAMA. 2017;317(5):531-534. doi:10.1001/jama.2016.16918

This survey study describes patients鈥� desire for and use of genetic counseling and testing after a new diagnosis of breast cancer.

Viewpoint

Population Health Equity: Rate and Burden, Race and Class

David Kindig, MD, PhD

Abstract Full Text

JAMA. 2017;317(5):467-468. doi:10.1001/jama.2016.19435

Although US racial and ethnic minorities have higher rates of poor health because of health care inequities, more low-income white individuals are affected because of greater population numbers. This Viewpoint explains that efforts to improve poor outcomes would be more effective if strategies were not based on proportions of race.

Responsible e-Prescribing Needs e-Discontinuation

Shira Fischer, MD, PhD; Adam Rose, MD

Abstract Full Text

JAMA. 2017;317(5):469-470. doi:10.1001/jama.2016.19908

This Viewpoint discusses the need for 鈥渆-discontinuation鈥� functionality to accompany electronic prescribing capabilities of electronic health records.

A Global Vaccine Injury Compensation System

Sam F. Halabi, JD, MPhil; Saad B. Omer, MBBS, MPH, PhD

Abstract Full Text

JAMA. 2017;317(5):471-472. doi:10.1001/jama.2016.19492

This Viewpoint discusses the benefits of establishing a global vaccine injury compensation system that is government and manufacturer supported to compensate individuals who experience vaccine injury.

Privatized Pharmaceutical Innovation vs Access to Essential Medicines: A Global Framework for Equitable Sharing of Benefits

Gian Luca Burci; Lawrence O. Gostin, JD

Abstract Full Text

JAMA. 2017;317(5):473-474. doi:10.1001/jama.2016.17994

This Viewpoint proposes a framework for promoting pharmaceutical innovation while ensuring access and affordability of new drugs on a global scale.

A Piece of My Mind

Mentee Missteps: Tales From the Academic Trenches

Valerie Vaughn, MD, MSc; Sanjay Saint, MD, MPH; Vineet Chopra, MD, MSc

Abstract Full Text

free access

JAMA. 2017;317(5):475-476. doi:10.1001/jama.2016.12384

Editorial

Whether to Intubate During Cardiopulmonary Resuscitation: Conventional Wisdom vs Big Data

Derek C. Angus, MD, MPH

Abstract Full Text

JAMA. 2017;317(5):477-478. doi:10.1001/jama.2016.20626

Video Laryngoscopy in the Intensive Care Unit: Seeing Is Believing, But That Does Not Mean It鈥檚 True

Brian O鈥橤ara, MD; Samuel Brown, MD, MS; Daniel Talmor, MD, MPH

Abstract Full Text

JAMA. 2017;317(5):479-480. doi:10.1001/jama.2016.21036

Sickle Cell Trait and Interpretation of Hemoglobin A_1c Levels

Anthony J. Bleyer, MD, MS; Joseph A. Aloi, MD

Abstract Full Text

JAMA. 2017;317(5):481-482. doi:10.1001/jama.2016.20994

Review

Diagnosis and Treatment of Pituitary Adenomas: A Review

Mark E. Molitch, MD

Abstract Full Text

JAMA. 2017;317(5):516-524. doi:10.1001/jama.2016.19699

This narrative review discusses the epidemiology, clinical characteristics, diagnosis, and treatment of pituitary adenomas.

JAMA Guide to Statistics and Methods

Equipoise in Research: Integrating Ethics and Science in Human Research

Alex John London, PhD

Abstract Full Text

has audio

JAMA. 2017;317(5):525-526. doi:10.1001/jama.2017.0016

This JAMA Guide to Statistics and Methods article reviews the concept of equipoise, which allows for randomization of interventions while also respecting the rights of human subjects in clinical research.

Podcast: JAMA Guide to Statistics and Methods
JAMAevidence: Guide to Statistics and Methods: Equipoise in Research鈥擨ntegrating Ethics and Science in Human Research

JAMA Clinical Challenge

A 24-Year-Old Man With a Left Frontal Brain Mass

Adrienne L. Carey, MD; Muhammed U. Khan, MD; N. Cary Engleberg, MD

Abstract Full Text

JAMA. 2017;317(5):527-528. doi:10.1001/jama.2016.19156

A 24-year-old man with 1 week of headache, gait imbalance, coordination difficulties, and personality changes tested positive for HIV, with a CT scan of the brain showing an aggressive solitary lesion extending through the corpus callosum. What would you do next?

Medical News & Perspectives

Sanctioned UK Trial of Mitochondrial Transfer Nears

Jeff Lyon

Abstract Full Text

JAMA. 2017;317(5):462-464. doi:10.1001/jama.2016.18680

This article discusses an experimental procedure that replaces maternal mitochondria with those from a donor to prevent inheritance of mitochondrial disease.

News From the Food and Drug Administration