August 1, 2023 Issue of JAMA

August 1, 2023, Vol 330, No. 5, Pages 393-480

This Week in JAMA

Audio Highlights

Abstract Full Text

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JAMA. 2023;330(5):e2215998. doi:10.1001/jama.2022.15998

Podcast: Vestibular Schwannoma Treatment, Genetics of Dilated Cardiomyopathy, Folic Acid to Prevent Neural Tube Defects, and more

Original Investigation

Upfront Radiosurgery vs a Wait-and-Scan Approach for Small- or Medium-Sized Vestibular Schwannoma: The V-REX Randomized Clinical Trial

Dhanushan Dhayalan, MD; Øystein Vesterli Tveiten, MD, PhD; Monica Finnkirk, RN; et al.

Abstract Full Text

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JAMA. 2023;330(5):421-431. doi:10.1001/jama.2023.12222

This randomized clinical trial evaluates whether upfront radiosurgery is more effective in reducing vestibular schwannoma tumor size than treatment delivered only when tumor growth has been detected radiographically.

Genetic Architecture of Dilated Cardiomyopathy in Individuals of African and European Ancestry

Elizabeth Jordan, MS; Daniel D. Kinnamon, PhD; Garrie J. Haas, MD; et al.

Abstract Full Text

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JAMA. 2023;330(5):432-441. doi:10.1001/jama.2023.11970

This study compares the rare variant genetic architecture of dilated cardiomyopathy (DCM) among patients with DCM who are of African ancestry compared with European ancestry.

Editorial
Diversifying the Genetic Landscape of Heart Disease
Catherine Tcheandjieu, DVM, PhD; Thomas P. Cappola, MD, ScM

JAMA

Longitudinal Follow-Up of Participants With Tobacco Exposure and Preserved Spirometry

William McKleroy, MD; Tracie Shing, PhD; Wayne H. Anderson, MEd, PhD; et al.

Abstract Full Text

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JAMA. 2023;330(5):442-453. doi:10.1001/jama.2023.11676

This study defines the natural history of persons with tobacco exposure and preserved spirometry aged 40 to 80 years who smoked cigarettes (>20 pack-years) with or without chronic obstructive pulmonary disease compared with controls without tobacco exposure or airflow obstruction.

Research Letter

Changes in the Number of Continuation Patents on Drugs Approved by the FDA

S. Sean Tu, JD, PhD; Aaron S. Kesselheim, MD, JD, MPH; Kathrine Wetherbee, BA; et al.

Abstract Full Text

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JAMA. 2023;330(5):469-470. doi:10.1001/jama.2023.11525

This study assesses the frequency of continuation patents on brand-name drugs approved by the US Food and Drug Administration from 2000 to 2015.

US Preventive Services Task Force

Recommendation Statement

Folic Acid Supplementation to Prevent Neural Tube Defects: US Preventive Services Task Force Reaffirmation Recommendation Statement

US Preventive Services Task Force

Abstract Full Text

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JAMA. 2023;330(5):454-459. doi:10.1001/jama.2023.12876

This 2023 Recommendation Statement from the US Preventive Services Task Force recommends that all persons planning to or who could become pregnant take a daily supplement containing 0.4 to 0.8 mg (400 to 800 渭g) of folic acid (A recommendation).

Podcast: USPSTF Recommendation: Folic Acid Supplementation for Prevention of Neural Tube Defects

Editorial
Reaffirming Recommendations for Folic Acid Supplementation: Everything Old Is New Again
David B. Nelson, MD; Catherine Y. Spong, MD

JAMA
- Podcast: USPSTF Recommendation: Folic Acid Supplementation for Prevention of Neural Tube Defects
Fully Effective Folic Acid Fortification
Joan K. Morris, PhD; Nicholas J. Wald, DSc (Med)

JAMA
- Podcast: USPSTF Recommendation: Folic Acid Supplementation for Prevention of Neural Tube Defects

Evidence Report

Folic Acid Supplementation to Prevent Neural Tube Defects: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Meera Viswanathan, PhD; Rachel Peragallo Urrutia, MD, MS; Kesha N. Hudson, PhD; et al.

Abstract Full Text

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JAMA. 2023;330(5):460-466. doi:10.1001/jama.2023.9864

This systematic review to support the 2023 US Preventive Services Task Force Recommendation Statement on folic acid supplementation to prevent neural tube defects summarizes published evidence on the benefits and harms of folic acid supplementation for persons who are planning to or could become pregnant.

Podcast: USPSTF Recommendation: Folic Acid Supplementation for Prevention of Neural Tube Defects

Editorial
Reaffirming Recommendations for Folic Acid Supplementation: Everything Old Is New Again
David B. Nelson, MD; Catherine Y. Spong, MD

JAMA
- Podcast: USPSTF Recommendation: Folic Acid Supplementation for Prevention of Neural Tube Defects
Fully Effective Folic Acid Fortification
Joan K. Morris, PhD; Nicholas J. Wald, DSc (Med)

JAMA
- Podcast: USPSTF Recommendation: Folic Acid Supplementation for Prevention of Neural Tube Defects

Viewpoint

The New Threat to Abortion Access in the United States鈥擳he Comstock Act

I. Glenn Cohen, JD; Eli Y. Adashi, MD, MS; Mary Ziegler, JD

Abstract Full Text

JAMA. 2023;330(5):405-406. doi:10.1001/jama.2023.9360

This Viewpoint explains the history of the Comstock Act, its use by those seeking to restrict abortion, and why it threatens abortion access in the US.

Over-the-Counter Oral Contraception as an Opportunity to Reduce Contraceptive Access Inequity

Kristyn Brandi, MD, MPH; Krishna K. Upadhya, MD, MPH; Stephanie B. Teal, MD, MPH

Abstract Full Text

JAMA. 2023;330(5):407-408. doi:10.1001/jama.2023.10825

This Viewpoint argues that making a progestin-only contraceptive pill available for sale as an over-the-counter product will help reduce logistic barriers to safe and effective birth control.

Integrating Medicare and Medicaid Coverage for Dual Eligibles鈥擱ecommendations for Reform

Eric T. Roberts, PhD; Kenton J. Johnston, MPH, PhD; Jose F. Figueroa, MD, MPH

Abstract Full Text

JAMA. 2023;330(5):409-410. doi:10.1001/jama.2023.8879

This Viewpoint highlights costly inefficiencies in delivery of care to patients who qualify to receive both Medicare and Medicaid and proposes more effective care models.

Private Actions to Protect Medicaid Live to See Another Day

Nicole Huberfeld, JD

Abstract Full Text

JAMA. 2023;330(5):411-412. doi:10.1001/jama.2023.12278

This Viewpoint discusses the recently decided Supreme Court Talevski lawsuit that affirmed that private parties can enforce federal Medicaid law against noncompliant states.

A Piece of My Mind

Finding Faith Through Listening

Andrea L. Merrill, MD

Abstract Full Text

JAMA. 2023;330(5):413-414. doi:10.1001/jama.2023.12385

In this narrative medicine essay, a surgical oncologist joins the hospital chaplain during his rounds to learn how to connect with patients who have strong faith in God, even when her own beliefs are uncertain.

Editorial

Diversifying the Genetic Landscape of Heart Disease

Catherine Tcheandjieu, DVM, PhD; Thomas P. Cappola, MD, ScM

Abstract Full Text

JAMA. 2023;330(5):415-416. doi:10.1001/jama.2023.12375

Fully Effective Folic Acid Fortification

Joan K. Morris, PhD; Nicholas J. Wald, DSc (Med)

Abstract Full Text

has audio

JAMA. 2023;330(5):417-418. doi:10.1001/jama.2023.12376

Podcast: USPSTF Recommendation: Folic Acid Supplementation for Prevention of Neural Tube Defects

Editorial
Reaffirming Recommendations for Folic Acid Supplementation: Everything Old Is New Again
David B. Nelson, MD; Catherine Y. Spong, MD

JAMA
- Podcast: USPSTF Recommendation: Folic Acid Supplementation for Prevention of Neural Tube Defects

Reaffirming Recommendations for Folic Acid Supplementation: Everything Old Is New Again

David B. Nelson, MD; Catherine Y. Spong, MD

Abstract Full Text

has audio

JAMA. 2023;330(5):419-420. doi:10.1001/jama.2023.12972

Podcast: USPSTF Recommendation: Folic Acid Supplementation for Prevention of Neural Tube Defects

Editorial
Fully Effective Folic Acid Fortification
Joan K. Morris, PhD; Nicholas J. Wald, DSc (Med)

JAMA
- Podcast: USPSTF Recommendation: Folic Acid Supplementation for Prevention of Neural Tube Defects

JAMA Clinical Challenge

Radiographic Absence of the Left Humeral Head

Adam D. Roche, MD; Orla C. Sheehan, MD, PhD

Abstract Full Text

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JAMA. 2023;330(5):467-468. doi:10.1001/jama.2023.12505

An older patient with history of surgical decompression for syringomyelia, poor mobility, and frequent falls presented with pain, numbness, and paresthesias in his left upper extremity. Radiograph showed complete absence of the left humeral head. What is the diagnosis, and what would you do next?

Medical News & Perspectives

Treating Bipolar Disorder Is Notoriously Difficult, but Research Underway Could Lead to New Options

Melissa Suran, PhD, MSJ

Abstract Full Text

JAMA. 2023;330(5):395-398. doi:10.1001/jama.2023.10057

This Medical News article discusses the difficulties of studying, diagnosing, and treating bipolar disorder and new research initiatives to improve diagnostic tests and treatments.

New Weight Loss Drugs Make Headlines at Diabetes Meeting

Jennifer Abbasi

Abstract Full Text

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JAMA. 2023;330(5):399-400. doi:10.1001/jama.2023.12718

This Medical News article discusses research presented at the American Diabetes Association鈥檚 83rd Annual Scientific Sessions program.

Podcast: Highlights From the American Diabetes Association Scientific Session 2023

Medical News in Brief

Opioids No Better Than Placebo at Relieving Back Pain

Emily Harris

Abstract Full Text

JAMA. 2023;330(5):401. doi:10.1001/jama.2023.12536

CDC: RSV Vaccine Recommended for Older People

Emily Harris

Abstract Full Text

JAMA. 2023;330(5):401. doi:10.1001/jama.2023.12537

National Health Care Leaders Will Develop AI Code of Conduct

Emily Harris

Abstract Full Text

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JAMA. 2023;330(5):401. doi:10.1001/jama.2023.12538

Few Supplemental Indications for Drugs Have Added Therapeutic Value

Emily Harris

Abstract Full Text

JAMA. 2023;330(5):401. doi:10.1001/jama.2023.12539

Medicaid Expansion Tied to Increased Palliative Care Use

Emily Harris

Abstract Full Text

JAMA. 2023;330(5):401-402. doi:10.1001/jama.2023.12540

Federal and State Agencies Crack Down on Health Care Fraud

Emily Harris

Abstract Full Text

JAMA. 2023;330(5):402. doi:10.1001/jama.2023.12541

FDA Greenlights First Cell Therapy for Adults With Type 1 Diabetes

Emily Harris

Abstract Full Text

JAMA. 2023;330(5):402. doi:10.1001/jama.2023.12542

Depression After Head Injury Might Be Separate Disorder

Emily Harris

Abstract Full Text

JAMA. 2023;330(5):402. doi:10.1001/jama.2023.12543

More Lean Muscle Might Reduce Alzheimer Disease Risk

Emily Harris

Abstract Full Text

JAMA. 2023;330(5):402. doi:10.1001/jama.2023.12544

Poetry and Medicine

Nepenthe

Scott C. Biggerstaff, DO

Abstract Full Text

JAMA. 2023;330(5):476. doi:10.1001/jama.2023.11522

JAMA Revisited

From the July 14, 1883, Inaugural Issue of JAMA

Abstract Full Text

JAMA. 2023;330(5):477. doi:10.1001/jama.2023.12664

JAMA Patient Page

Folic Acid to Prevent Neural Tube Defects

Jill Jin, MD, MPH

Abstract Full Text

free access has audio

JAMA. 2023;330(5):480. doi:10.1001/jama.2023.14061

This JAMA Patient Page describes the pros and cons of folic acid supplementation during pregnancy to lower risk of fetal neural tube defects.

Podcast: USPSTF Recommendation: Folic Acid Supplementation for Prevention of Neural Tube Defects

Editorial
Reaffirming Recommendations for Folic Acid Supplementation: Everything Old Is New Again
David B. Nelson, MD; Catherine Y. Spong, MD

JAMA
- Podcast: USPSTF Recommendation: Folic Acid Supplementation for Prevention of Neural Tube Defects
Fully Effective Folic Acid Fortification
Joan K. Morris, PhD; Nicholas J. Wald, DSc (Med)

JAMA
- Podcast: USPSTF Recommendation: Folic Acid Supplementation for Prevention of Neural Tube Defects