December 12, 2023 Issue of JAMA

December 12, 2023, Vol 330, No. 22, Pages 2135-2224

This Week in JAMA

Audio Highlights

Abstract Full Text

free access online only has audio

JAMA. 2023;330(22):e2216151. doi:10.1001/jama.2022.16151

Podcast: Antithrombotic Regimens for LVADs, Cannabis in Pregnancy, Hepatitis C in Black Individuals, and more

Original Investigation

Aspirin and Hemocompatibility Events With a Left Ventricular Assist Device in Advanced Heart Failure: The ARIES-HM3 Randomized Clinical Trial

Mandeep R. Mehra, MBBS, MSc; Ivan Netuka, MD, PhD; Nir Uriel, MD, MSc; et al.

Abstract Full Text

free access

JAMA. 2023;330(22):2171-2181. doi:10.1001/jama.2023.23204

This randomized clinical trial examines the safety of the exclusion of aspirin as part of an antithrombotic regimen including a vitamin K antagonist with a fully magnetically levitated left ventricular assist device.

Editorial
Addition by Subtraction in Mechanical Cardiac Support
G. Michael Felker, MD, MHS; Joseph G. Rogers, MD

JAMA

Metformin Plus Insulin for Preexisting Diabetes or Gestational Diabetes in Early Pregnancy: The MOMPOD Randomized Clinical Trial

Kim A. Boggess, MD; Arielle Valint, MS; Jerrie S. Refuerzo, MD; et al.

Abstract Full Text

free access

JAMA. 2023;330(22):2182-2190. doi:10.1001/jama.2023.22949

This randomized clinical trial compares the effect of insulin plus metformin vs insulin and placebo in reducing the odds of adverse neonatal outcomes in pregnant adults with preexisting type 2 diabetes or diabetes identified in early pregnancy.

Editorial
Metformin for Diabetes in Pregnancy: Are We Closer to Defining Its Role?
Denice S. Feig, MD

JAMA
- Podcast: Metformin for Diabetes in Pregnancy

Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function

Torri D. Metz, MD, MS; Amanda A. Allshouse, MS; Gwendolyn A. McMillin, PhD; et al.

Abstract Full Text

free access has active quiz has audio

JAMA. 2023;330(22):2191-2199. doi:10.1001/jama.2023.21146

This observational analysis evaluates the association between maternal cannabis use and adverse pregnancy outcomes known to be related to placental function among nulliparous individuals treated at US medical centers with stored urine samples and available pregnancy outcome data.

Podcast: Risks Associated With Cannabis Exposure During Pregnancy

Research Letter

Prices for Common Services at Quaternary vs Nonquaternary Hospitals

Brandon W. Yan, MD, MPH; Maximilian J. Pany, PhD; Leemore S. Dafny, PhD; et al.

Abstract Full Text

free access

JAMA. 2023;330(22):2211-2213. doi:10.1001/jama.2023.17249

This study uses commercial claims data to assess whether quaternary hospitals charge higher prices for common, unspecialized services also offered by nonquaternary hospitals.

School Performance in Third Grade After a Full-Day vs Part-Day Preschool Program

Arthur J. Reynolds, PhD; Nicole E. Smerillo, PhD; Suh-Ruu Ou, PhD; et al.

Abstract Full Text

free access

JAMA. 2023;330(22):2214-2215. doi:10.1001/jama.2023.20010

This study assesses whether learning gains associated with full-day preschool were sustained through third grade by analyzing achievement scores and need for remediation.

Viewpoint

Health Professionals and War in the Middle East

Matthew K. Wynia, MD, MPH

Abstract Full Text

JAMA. 2023;330(22):2155-2156. doi:10.1001/jama.2023.24247

In this Viewpoint, the author examines whether health care professionals have any responsibilities to speak out about the conflict in the Middle East.

Editor's Note
Reporting on Health and War in Medical Journals
Gregory Curfman, MD; Kirsten Bibbins-Domingo, PhD, MD, MAS

JAMA

Down Syndrome in a New Era for Alzheimer Disease

Michael S. Rafii, MD, PhD; Juan Fortea, MD, PhD

Abstract Full Text

JAMA. 2023;330(22):2157-2158. doi:10.1001/jama.2023.22924

This Viewpoint explains the genetic association between Alzheimer disease and Down syndrome and the negative impact of excluding people with Down syndrome from clinical trials on treatment for Alzheimer disease.

AI in Medicine

AI Alone Will Not Reduce the Administrative Burden of Health Care

Kevin A. Schulman, MD; Perry Kent Nielsen Jr; Kavita Patel, MD, MPH

Abstract Full Text

free access

JAMA. 2023;330(22):2159-2160. doi:10.1001/jama.2023.23809

This Viewpoint considers AI鈥檚 limits in solving the medical billing quagmire and argues that standardizing health insurance claim forms and simplifying billing must occur before AI can shoulder the load.

Alternative Payment Models in Pregnancy to Improve Outcomes and Advance Equity

Jordan S. Stone, MD; Arina E. Chesnokova, MD, MPH; Sindhu K. Srinivas, MD, MSCE

Abstract Full Text

JAMA. 2023;330(22):2161-2162. doi:10.1001/jama.2023.22800

This Viewpoint reviews the state of alternative payment models (APMs) applied to pregnancy and proposes clinical and policy objectives that could guide model design going forward.

A Piece of My Mind

Being Patient

Tamara A. Huson, MD

Abstract Full Text

JAMA. 2023;330(22):2163-2164. doi:10.1001/jama.2023.24051

In this narrative medicine essay, a family medicine physician鈥檚 experience while undergoing a breast biopsy inspires her to build trust with her patients by listening and counseling more.

Editorial

Addition by Subtraction in Mechanical Cardiac Support

G. Michael Felker, MD, MHS; Joseph G. Rogers, MD

Abstract Full Text

JAMA. 2023;330(22):2165-2166. doi:10.1001/jama.2023.22490

Metformin for Diabetes in Pregnancy: Are We Closer to Defining Its Role?

Denice S. Feig, MD

Abstract Full Text

has audio

JAMA. 2023;330(22):2167-2169. doi:10.1001/jama.2023.18589

Podcast: Metformin for Diabetes in Pregnancy

Review

Hepatitis C in Black Individuals in the US: A Review

Oluwaseun Falade-Nwulia, MBBS, MPH; Sharon M. Kelly, PhD; Sasraku Amanor-Boadu, MD, MPH; et al.

Abstract Full Text

has active quiz

JAMA. 2023;330(22):2200-2208. doi:10.1001/jama.2023.21981

This review summarizes evidence regarding Black race and inequities in outcomes of hepatitis C virus (HCV) infection because of the high prevalence and absolute number of annual HCV-related deaths in Black populations relative to other racial and ethnic minority groups.

Editor's Note
Black Race and Hepatitis C鈥攁 New Focus for JAMA Narrative Reviews
Mary M. McDermott, MD; Kirsten Bibbins-Domingo, PhD, MD, MAS

JAMA

JAMA Clinical Challenge

Violaceous Nodules on the Right Leg and Foot

Tai-Li Chen, MD; Hao-Kai Chuang, MD; Chen-Yi Wu, MD, PhD

Abstract Full Text

has active quiz

JAMA. 2023;330(22):2209-2210. doi:10.1001/jama.2023.20118

A patient with a history of bullous pemphigoid treated with oral prednisolone presented with multiple round, dark brown to violaceous-colored firm nodules on the right leg and 2 nodular masses with hemorrhagic crusts on the right foot. Complete blood cell count and creatinine and liver function test results were normal, and results of HIV antibody testing were negative. What is the diagnosis and what would you do next?

Editor's Note

Black Race and Hepatitis C鈥攁 New Focus for JAMA Narrative Reviews

Mary M. McDermott, MD; Kirsten Bibbins-Domingo, PhD, MD, MAS

Abstract Full Text

free access

JAMA. 2023;330(22):2170. doi:10.1001/jama.2023.22464

Cover Me With Words鈥擡xpressing Pain in Poetry

Rafael Campo, MD, MA

Abstract Full Text

free access

JAMA. 2023;330(22):2220. doi:10.1001/jama.2023.21666

Medical News & Perspectives

AI in Medicine

Clinical AI Tools Must Be Fed the Right Data, Stanford Health Care's Chief Data Scientist Says

Rebecca Voelker, MSJ; Yulin Hswen, ScD, MPH

Abstract Full Text

free access has multimedia has audio

JAMA. 2023;330(22):2137-2139. doi:10.1001/jama.2023.19297

In this Medical News interview, Stanford Health Care鈥檚 chief data scientist Nigam Shah, MBBS, PhD, discusses ways to train and evaluate artificial intelligence models for use in health care.

Video: AI and Clinical Practice鈥攖he Learning Health System and AI

Podcast: AI and Clinical Practice鈥攖he Learning Health System and AI

Editorial
AI in Medicine鈥�JAMA鈥檚 Focus on Clinical Outcomes, Patient-Centered Care, Quality, and Equity
Rohan Khera, MD, MS; Atul J. Butte, MD, PhD; Michael Berkwits, MD, MSCE; Yulin Hswen, ScD, MPH; Annette Flanagin, RN, MA; Hannah Park; Gregory Curfman, MD; Kirsten Bibbins-Domingo, PhD, MD, MAS

JAMA

As Semaglutide鈥檚 Popularity Soars, Rare but Serious Adverse Effects Are Emerging

Kate Ruder, MSJ

Abstract Full Text

has audio

JAMA. 2023;330(22):2140-2142. doi:10.1001/jama.2023.16620

This Medical News article discusses Wegovy, Ozempic, and other GLP-1 receptor agonists used for weight management and type 2 diabetes.

Podcast: Obesity Management in Primary Care
Podcast: November 2023 Medical News Summary

FDA Green-Lights Tirzepatide, Marketed as Zepbound, for Chronic Weight Management

Jennifer Abbasi

Abstract Full Text

has audio

JAMA. 2023;330(22):2143-2144. doi:10.1001/jama.2023.24539

This Medical News article discusses the November 8 US Food and Drug Administration approval of the drug tirzepatide for chronic weight management in people with obesity or overweight with weight-related conditions.

Podcast: Obesity Management in Primary Care
Podcast: November 2023 Medical News Summary