February 21, 2023 Issue of JAMA

糖心vlog

February 21, 2023, Vol 329, No. 7, Pages 525-602

This Week in JAMA

Audio Highlights

Abstract Full Text

free access online only has audio

JAMA. 2023;329(7):e2215800. doi:10.1001/jama.2022.15800

Podcast: Aspirin Discontinuation at 24 to 28 Weeks鈥� Gestation in Pregnancies at High Risk of Preterm Preeclampsia, African Ancestry鈥揝pecific APOE Variants and Risk of Alzheimer Disease, Review of Primary Brain Malignancies, and more

Original Investigation

Aspirin Discontinuation at 24 to 28 Weeks鈥� Gestation in Pregnancies at High Risk of Preterm Preeclampsia: A Randomized Clinical Trial

Manel Mendoza, PhD; Erika Bonacina, MD; Pablo Garcia-Manau, MD; et al.

Abstract Full Text

free access

JAMA. 2023;329(7):542-550. doi:10.1001/jama.2023.0691

This randomized clinical trial aims to determine whether aspirin discontinuation in pregnant individuals with normal soluble fms-like tyrosine kinase鈥�1 to placental growth factor (sFlt-1:PlGF) ratio between 24 and 28 weeks of gestation was noninferior to aspirin continuation to prevent preterm preeclampsia.

Editorial
Biomarkers and the Risk of Preeclampsia
Ukachi N. Emeruwa, MD, MPH; Cynthia Gyamfi-Bannerman, MD, MS; Louise C. Laurent, MD, PhD

JAMA

Association of African Ancestry鈥揝pecific APOE Missense Variant R145C With Risk of Alzheimer Disease

Yann Le Guen, PhD; Ana-Caroline Raulin, PhD; Mark W. Logue, PhD; et al.

Abstract Full Text

free access

JAMA. 2023;329(7):551-560. doi:10.1001/jama.2023.0268

This exploratory case-control study assesses the association of APOE missense variants with risk of Alzheimer disease among individuals of African ancestry with the APOE 蔚3/蔚4 genotype.

History of Low Hourly Wage and All-Cause Mortality Among Middle-aged Workers

Katrina L. Kezios, PhD; Peiyi Lu, PhD; Sebastian Calonico, PhD; et al.

Abstract Full Text

free access

JAMA. 2023;329(7):561-573. doi:10.1001/jama.2023.0367

This longitudinal study involving US workers collected wage information during a portion of peak earning years and examined whether a history of low-wage earning was associated with mortality risk.

Research Letter

Dissemination of the Results of Pediatric Clinical Trials Funded by the US National Institutes of Health

Chris A. Rees, MD, MPH; Claire Narang, BS; Adrianna Westbrook, MPH; et al.

Abstract Full Text

free access

JAMA. 2023;329(7):590-592. doi:10.1001/jama.2022.24025

This study examines practices related to trial registration and results submission in ClinicalTrials.gov and publication of pediatric clinical trials funded by the National Institutes of Health.

Viewpoint

Assessing鈥攁nd Extending鈥擟alifornia鈥檚 Insulin Manufacturing Initiative

Jacob S. Sherkow, JD, MA; Eli Y. Adashi, MD, MS; I. Glenn Cohen, JD

Abstract Full Text

JAMA. 2023;329(7):533-534. doi:10.1001/jama.2023.0013

This Viewpoint reviews California鈥檚 recently proposed CalRx initiative to manufacture biosimilar insulin, highlights challenges facing the initiative, and suggests ways in which, if successful, the initiative could serve as a model for state-managed development of drugs other than insulin, reduce drug prices, and provide other benefits.

The Importance of Shifting Sepsis Quality Measures From Processes to Outcomes

Michael Klompas, MD, MPH; Chanu Rhee, MD, MPH; Mervyn Singer, MD

Abstract Full Text

JAMA. 2023;329(7):535-536. doi:10.1001/jama.2023.0340

This Viewpoint discusses the failure of the Centers for Medicare & Medicaid Services鈥� SEP-1 sepsis outcome improvement initiative to improve patients鈥� sepsis outcomes and suggests changing the focus of sepsis quality metrics from processes to outcomes.

A Piece of My Mind

Sanctity

Huma Farid, MD

Abstract Full Text

JAMA. 2023;329(7):537-538. doi:10.1001/jama.2022.24989

In this narrative medicine essay, an obstetrician finds relief from the frenetic intrusions of text messages, pages, and emails when in the operating room, where all devices are turned off and all her attention is turned on to her patient.

Editorial

Biomarkers and the Risk of Preeclampsia

Ukachi N. Emeruwa, MD, MPH; Cynthia Gyamfi-Bannerman, MD, MS; Louise C. Laurent, MD, PhD

Abstract Full Text

JAMA. 2023;329(7):539-541. doi:10.1001/jama.2022.24906

Review

Glioblastoma and Other Primary Brain Malignancies in Adults: A Review

Lauren R. Schaff, MD; Ingo K. Mellinghoff, MD

Abstract Full Text

has active quiz has audio

JAMA. 2023;329(7):574-587. doi:10.1001/jama.2023.0023

This review summarizes current evidence regarding diagnosis and treatment of primary malignant brain tumors in adults.

Podcast: Glioblastoma and Other Primary Brain Malignancies in Adults

JAMA Insights

Women's Health

Risk Factors, Symptoms, and Treatment of Lactational Mastitis

Adetola F. Louis-Jacques, MD; Margarita Berwick, MD; Katrina B. Mitchell, MD

Abstract Full Text

has active quiz

JAMA. 2023;329(7):588-589. doi:10.1001/jama.2023.0004

This JAMA Insights Clinical Update reviews the risk factors for and symptoms of lactational mastitis and provides a potential treatment algorithm.

Medical News & Perspectives

New HIV Vaccine Approach Safely Stimulated Rare Precursors to Broadly Neutralizing Antibodies

Melissa Suran, PhD, MSJ

Abstract Full Text

JAMA. 2023;329(7):527-528. doi:10.1001/jama.2022.23242

This Medical News article discusses a clinical trial for an HIV vaccine that uses germline targeting, a novel technique to induce rare immune cell precursors of broadly neutralizing antibodies.

Study Finds US Households, Especially in Rural Areas, Increasingly Shop at Dollar Stores for Food

Kate Ruder, MSJ

Abstract Full Text

JAMA. 2023;329(7):529-530. doi:10.1001/jama.2023.0642

This Medical News article discusses a new study of household food purchasing trends from 2008 to 2020.

Medical News in Brief

National Academies: Expand US Wastewater Disease Surveillance

Howard Larkin

Abstract Full Text

JAMA. 2023;329(7):531. doi:10.1001/jama.2023.0739

High COVID-19 Rates Prompt Call for Better Nursing Home Protections

Howard Larkin

Abstract Full Text

free access

JAMA. 2023;329(7):531. doi:10.1001/jama.2023.0740

Agent Slows Glioblastoma Tumors in Mice by Blocking Fat Metabolism

Howard Larkin

Abstract Full Text

JAMA. 2023;329(7):531. doi:10.1001/jama.2023.0741

Hybrid Immunity More Protective Than Prior SARS-CoV-2 Infection Alone

Howard Larkin

Abstract Full Text

JAMA. 2023;329(7):531. doi:10.1001/jama.2023.0743

New Report on Mpox Cases Leading Up to 2022 Global Outbreak

Howard Larkin

Abstract Full Text

JAMA. 2023;329(7):531. doi:10.1001/jama.2023.0744

Nearly 500鈥�000 in UK May Have Missed Blood Pressure Drugs

Howard Larkin

Abstract Full Text

JAMA. 2023;329(7):531-532. doi:10.1001/jama.2023.0745

Both High- and Low-Dose Exercise Therapy Help Knee Osteoarthritis

Howard Larkin

Abstract Full Text

JAMA. 2023;329(7):532. doi:10.1001/jama.2023.0746

Vasopressors or High-Volume IV Fluids Both Effective for Sepsis

Howard Larkin

Abstract Full Text

JAMA. 2023;329(7):532. doi:10.1001/jama.2023.0747

Newly Discovered Host-Cell Factor Could Be a COVID-19 Treatment Target

Howard Larkin

Abstract Full Text

free access

JAMA. 2023;329(7):532. doi:10.1001/jama.2023.0748

Poetry and Medicine

The Hole

顿别颈谤诲谤别翱鈥机辞苍苍辞谤, 惭贵础

Abstract Full Text

JAMA. 2023;329(7):597. doi:10.1001/jama.2023.0212

JAMA Revisited

Seasonal Variability of Disease

Abstract Full Text

JAMA. 2023;329(7):598. doi:10.1001/jama.2022.15801

JAMA Patient Page

What Is Guillain-Barr茅 Syndrome?

Revital Marcus, MD

Abstract Full Text

free access

JAMA. 2023;329(7):602. doi:10.1001/jama.2022.24232

This JAMA Patient Page describes the autoimmune disease Guillain-Barr茅 syndrome and its risk factors, diagnosis, treatment, and prognosis.

Comment & Response

Review of Pulmonary Embolism

Mateo Porres-Aguilar, MD; Javier E. Anaya-Ayala, MD, MS; Debabrata Mukherjee, MD, MS

Abstract Full Text

JAMA. 2023;329(7):592. doi:10.1001/jama.2022.22235

Review of Pulmonary Embolism

Wei Xiong, MD, PhD

Abstract Full Text

JAMA. 2023;329(7):592-593. doi:10.1001/jama.2022.22232

Review of Pulmonary Embolism

David R. Vinson, MD; Jeffrey D. Sperling, MD, MS; Nareg H. Roubinian, MD, MPH

Abstract Full Text

JAMA. 2023;329(7):593. doi:10.1001/jama.2022.22238

Review of Pulmonary Embolism鈥擱eply

Yonathan Freund, MD, PhD; Fleur Cohen-Aubart, MD, PhD; Ben Bloom, MD, PhD

Abstract Full Text

JAMA. 2023;329(7):593-594. doi:10.1001/jama.2022.22241

Roflumilast Cream vs Vehicle Cream and Chronic Plaque Psoriasis

Brandon Smith, BA; Michael R. Collier, BS; Jashin J. Wu, MD

Abstract Full Text

JAMA. 2023;329(7):594-595. doi:10.1001/jama.2022.22646

Roflumilast Cream vs Vehicle Cream and Chronic Plaque Psoriasis鈥擱eply

Mark G. Lebwohl, MD; Adelaide A. Hebert, MD; Melinda J. Gooderham, MD

Abstract Full Text

JAMA. 2023;329(7):595. doi:10.1001/jama.2022.22649

Notice of Retraction and Replacement. Ellison-Barnes et al. Trends in Obesity Prevalence Among Adults Aged 18 Through 25 Years, 1976-2018. JAMA. 2021;326(20):2073-2074

Alejandra Ellison-Barnes, MD, MPH; Sara Johnson, PhD, MPH; Kimberly Gudzune, MD, MPH

Abstract Full Text

free access

JAMA. 2023;329(7):595-596. doi:10.1001/jama.2022.23438

November 2024 - July 1883

Decade

Year

Issue

February 21, 2023, Vol 329, No. 7, Pages 525-602

Women's Health

Latest from the USPSTF