November 7, 2023 Issue of JAMA

November 7, 2023, Vol 330, No. 17, Pages 1601-1703

This Week in JAMA

Audio Highlights

Abstract Full Text

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JAMA. 2023;330(17):e2216106. doi:10.1001/jama.2022.16106

Podcast: Adding Tirzepatide vs Prandial Insulin to Basal Insulin, Beta-Blockers in Septic Shock, USPSTF on Oral Health Screening, and more

Original Investigation

Tirzepatide vs Insulin Lispro Added to Basal Insulin in Type 2 Diabetes: The SURPASS-6 Randomized Clinical Trial

Julio Rosenstock, MD; Juan P. Frías, MD; Helena W. Rodbard, MD; et al.

Abstract Full Text

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JAMA. 2023;330(17):1631-1640. doi:10.1001/jama.2023.20294

This study examines the efficacy and safety of tirzepatide vs insulin lispro adjunctive therapy to insulin glargine among those receiving basal insulin with inadequately controlled type 2 diabetes.

Caring for the Critically Ill Patient

Landiolol and Organ Failure in Patients With Septic Shock: The STRESS-L Randomized Clinical Trial

Tony Whitehouse, MD; Anower Hossain, PhD; Gavin D. Perkins, MD; et al.

Abstract Full Text

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JAMA. 2023;330(17):1641-1652. doi:10.1001/jama.2023.20134

This clinical trial assesses whether landiolol for patients with tachycardia and established septic shock requiring prolonged vasopressor support reduces the risk of organ failure.

Editorial
尾-Blockers in Patients With Sepsis: Putting the Puzzle Together, Piece by Piece
Steven M. Hollenberg, MD

JAMA

Pharmacotherapy for Alcohol Use Disorder: A Systematic Review and Meta-Analysis

Melissa McPheeters, PhD, MPH; Elizabeth A. O鈥機onnor, PhD; Sean Riley, MSc, MA; et al.

Abstract Full Text

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JAMA. 2023;330(17):1653-1665. doi:10.1001/jama.2023.19761

This systematic review and meta-analysis evaluates efficacy and comparative efficacy of 9 therapies for alcohol use disorder (AUD).

Research Letter

Synthetic Cooling Agent and Other Flavor Additives in 鈥淣on-Menthol鈥� Cigarettes Marketed in California and Massachusetts After Menthol Cigarette Bans

Sairam V. Jabba, DVM, PhD; Hanno C. Erythropel, PhD; Paul T. Anastas, PhD; et al.

Abstract Full Text

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JAMA. 2023;330(17):1689-1691. doi:10.1001/jama.2023.17134

This study uses a bioassay and chemical analysis to determine the proportion of newly introduced 鈥渘on-menthol鈥� cigarette brands with sensory cooling effects, cooling agents added, and any other flavor additives after menthol cigarette bans.

Invited Commentary
Understanding the Potential Impact of a Menthol Cigarette Ban on Young People
Cristine D. Delnevo, PhD, MPH

JAMA Netw Open

Trends and Outcomes of Assisted Reproductive Technology Cycles Using a Gestational Carrier Between 2014 and 2020

Lisa M. Shandley, MD, MSc; Carol E. DeSantis, MPH; Jacqueline C. Lee, MD; et al.

Abstract Full Text

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JAMA. 2023;330(17):1691-1694. doi:10.1001/jama.2023.11023

This study used national surveillance data from the Society for Assisted Reproductive Technology to describe trends and outcomes in assisted reproductive technology cycles using a gestational carrier vs those not using a gestational carrier.

US Preventive Services Task Force

Recommendation Statement

Screening and Preventive Interventions for Oral Health in Children and Adolescents Aged 5 to 17 Years: US Preventive Services Task Force Recommendation Statement

US Preventive Services Task Force

Abstract Full Text

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JAMA. 2023;330(17):1666-1673. doi:10.1001/jama.2023.21408

This 2023 Recommendation Statement from the US Preventive Services Task Force concludes that the current evidence is insufficient to assess the balance of benefits and harms of routine screening and preventive interventions performed by primary care clinicians for oral health conditions, including dental caries, in children and adolescents aged 5 to 17 years (I statement).

Podcast: USPSTF Recommendations: Screening and Preventive Interventions for Oral Health in Adults and in Children and Adolescents Aged 5 to 17 Years

Editorial
A Call for More Oral Health Research in Primary Care
Michael S. Reddy, DMD, DMSc; Rena N. D鈥橲ouza, DDS, MS, PhD; Jennifer Webster-Cyriaque, DDS, PhD

JAMA
- Podcast: USPSTF Recommendations: Screening and Preventive Interventions for Oral Health in Adults and in Children and Adolescents Aged 5 to 17 Years

Evidence Report

Screening, Referral, Behavioral Counseling, and Preventive Interventions for Oral Health in Children and Adolescents Aged 5 to 17 Years: A Systematic Review for the US Preventive Services Task Force

Roger Chou, MD; Christina Bougatsos, MPH; Jessica Griffin, MS; et al.

Abstract Full Text

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JAMA. 2023;330(17):1674-1686. doi:10.1001/jama.2023.20435

This systematic review to support the 2023 US Preventive Services Task Force Recommendation Statement on oral health screening and prevention in children and adolescents summarizes published evidence on the benefits and harms of screening, referral, behavioral counseling, and preventive interventions for oral health in asymptomatic children and adolescents aged 5 to 17 years.

Podcast: USPSTF Recommendations: Screening and Preventive Interventions for Oral Health in Adults and in Children and Adolescents Aged 5 to 17 Years

Editorial
A Call for More Oral Health Research in Primary Care
Michael S. Reddy, DMD, DMSc; Rena N. D鈥橲ouza, DDS, MS, PhD; Jennifer Webster-Cyriaque, DDS, PhD

JAMA
- Podcast: USPSTF Recommendations: Screening and Preventive Interventions for Oral Health in Adults and in Children and Adolescents Aged 5 to 17 Years

Viewpoint

AI in Medicine

Algorithms at the Gate鈥擱adiology鈥檚 AI Adoption Dilemma

Saurabh Jha, MBBS, MS

Abstract Full Text

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JAMA. 2023;330(17):1615-1616. doi:10.1001/jama.2023.16049

In this Viewpoint a radiologist surveys the ascent of artificial intelligence (AI) in imaging and what the future likely holds for AI in this discipline.

Podcast: AI in Radiology: Enhancing Analysis, Education, and Access

The Centers for Disease Control and Prevention鈥檚 Hospital Sepsis Program Core Elements

Hallie C. Prescott, MD, MSc; Patricia J. Posa, RN, BSN, MSA, CCRN-K; Raymund Dantes, MD, MPH

Abstract Full Text

JAMA. 2023;330(17):1617-1618. doi:10.1001/jama.2023.16693

This Viewpoint discusses Hospital Sepsis Program Core Elements, a set of guidance provided by the Centers for Disease Control and Prevention to help hospitals develop multiprofessional programs that monitor and optimize management and outcomes of sepsis.

The Inflation Reduction Act and Access to High-Cost Cardiovascular Therapies

Dhruv S. Kazi, MD, MSc, MS; Rishi K. Wadhera, MD, MPP, MPhil; Benjamin N. Rome, MD, MPH

Abstract Full Text

JAMA. 2023;330(17):1619-1620. doi:10.1001/jama.2023.19129

This Viewpoint discusses how the price negotiation for certain drugs under the Inflation Reduction Act will provide a unique opportunity to enhance access to therapies for older patients with cardiovascular conditions and diabetes.

Medicare鈥檚 Historic Prescription Drug Price Negotiations

Lawrence O. Gostin, JD; James G. Hodge Jr, JD, LLM; Andrew J. Twinamatsiko, JD

Abstract Full Text

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JAMA. 2023;330(17):1621-1622. doi:10.1001/jama.2023.19506

This Viewpoint evaluates the legal claims and policy implications of historic drug price negotiations possible with the Inflation Reduction Act of 2022.

Podcast: Medicare鈥檚 Historic Prescription Drug Price Negotiations

Aligning Prevention Evidence Gaps With Prevention Research

Wanda Nicholson, MD, MPH, MBA; Michael J. Barry, MD; Carol M. Mangione, MD, MSPH

Abstract Full Text

JAMA. 2023;330(17):1623-1624. doi:10.1001/jama.2023.20879

This Viewpoint describes the development of tools to communicate actionable steps to address research needs and gaps for USPSTF recommendations that have insufficient evidence to make definitive guidance.

A Piece of My Mind

The Other Side of the Bounce Back

Kimberly D. Manning, MD

Abstract Full Text

JAMA. 2023;330(17):1625-1626. doi:10.1001/jama.2023.20532

In this narrative medicine essay, an internist becomes sensitized to the harshness of inside medical language when the expression bounce back is applied to her father鈥檚 return to the hospital shortly after his discharge.

Editorial

尾-Blockers in Patients With Sepsis: Putting the Puzzle Together, Piece by Piece

Steven M. Hollenberg, MD

Abstract Full Text

JAMA. 2023;330(17):1627-1628. doi:10.1001/jama.2023.20455

A Call for More Oral Health Research in Primary Care

Michael S. Reddy, DMD, DMSc; Rena N. D鈥橲ouza, DDS, MS, PhD; Jennifer Webster-Cyriaque, DDS, PhD

Abstract Full Text

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JAMA. 2023;330(17):1629-1630. doi:10.1001/jama.2023.22005

Podcast: USPSTF Recommendations: Screening and Preventive Interventions for Oral Health in Adults and in Children and Adolescents Aged 5 to 17 Years

JAMA Clinical Guidelines Synopsis

Diagnosis and Management of Nonalcoholic Fatty Liver Disease

Peggy B. Leung, MD; Andrew M. Davis, MD, MPH; Sonal Kumar, MD, MPH

Abstract Full Text

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JAMA. 2023;330(17):1687-1688. doi:10.1001/jama.2023.17935

This JAMA Clinical Guidelines Synopsis summarizes the American Association of Clinical Endocrinology鈥檚 2022 clinical practice guideline for diagnosis and management of nonalcoholic fatty liver disease.

Medical News & Perspectives

AI in Medicine

New AI Tools Must Have Health Equity in Their DNA

Yulin Hswen, ScD, MPH; Rebecca Voelker, MSJ

Abstract Full Text

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JAMA. 2023;330(17):1604-1607. doi:10.1001/jama.2023.19293

In this Medical News interview, Kedar S. Mate, MD, president and chief executive officer of the Institute for Healthcare Improvement, discusses patient safety and health care equity in the development of clinical AI tools.

Video: AI and Clinical Practice鈥擨mproving Health Care Quality and Equity

Podcast: AI and Clinical Practice鈥擨mproving Health Care Quality and Equity

Editorial
AI in Medicine鈥�JAMA鈥檚 Focus on Clinical Outcomes, Patient-Centered Care, Quality, and Equity
Rohan Khera, MD, MS; Atul J. Butte, MD, PhD; Michael Berkwits, MD, MSCE; Yulin Hswen, ScD, MPH; Annette Flanagin, RN, MA; Hannah Park; Gregory Curfman, MD; Kirsten Bibbins-Domingo, PhD, MD, MAS

JAMA

Climate Change and Health

As Climate Change Takes a Toll on Mental Health in Africa, Experts Call for More Research and Interventions

Melissa Suran, PhD, MSJ

Abstract Full Text

JAMA. 2023;330(17):1608-1610. doi:10.1001/jama.2023.19182

This Medical News article discusses how climate change is affecting mental health in Africa and what efforts are needed to mitigate the effects.

Medical News in Brief

COVID-19 Hospitalizations Up Among Older Adults

Emily Harris

Abstract Full Text

JAMA. 2023;330(17):1611. doi:10.1001/jama.2023.19796

Esketamine More Effective Than Quetiapine for Hard-to-Treat Depression

Emily Harris

Abstract Full Text

JAMA. 2023;330(17):1611. doi:10.1001/jama.2023.19797

Previous COVID-19 Linked With Autoimmune Conditions

Emily Harris

Abstract Full Text

JAMA. 2023;330(17):1611. doi:10.1001/jama.2023.19798

New-Onset Atrial Fibrillation During Hospitalization Likely to Recur

Emily Harris

Abstract Full Text

JAMA. 2023;330(17):1611. doi:10.1001/jama.2023.19799

Vaccination Hesitancy Increasing Among Pregnant Women

Emily Harris

Abstract Full Text

JAMA. 2023;330(17):1611-1612. doi:10.1001/jama.2023.19800

Mental Illness Might Be Early Feature of Multiple Sclerosis

Emily Harris

Abstract Full Text

JAMA. 2023;330(17):1612. doi:10.1001/jama.2023.19801

Short Bouts of Movement Linked With Lower Risk of Death

Emily Harris

Abstract Full Text

JAMA. 2023;330(17):1612. doi:10.1001/jama.2023.19802

Many Older People Disagree With Life Expectancy鈥揃ased Cancer Screening

Emily Harris

Abstract Full Text

JAMA. 2023;330(17):1612. doi:10.1001/jama.2023.19803

Cancer Diagnoses, Pathology Reports Dropped Early in Pandemic

Emily Harris

Abstract Full Text

JAMA. 2023;330(17):1612. doi:10.1001/jama.2023.19804

Poetry and Medicine

Enough

Katelynn M. Smith, MD

Abstract Full Text

JAMA. 2023;330(17):1698. doi:10.1001/jama.2023.19419

JAMA Revisited

The Effects of Extremes of Temperature and Humidity

Abstract Full Text

JAMA. 2023;330(17):1699. doi:10.1001/jama.2022.16107

JAMA Patient Page

Dental Caries in Adults, Adolescents, and Children

Jill Jin, MD, MPH

Abstract Full Text

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JAMA. 2023;330(17):1703. doi:10.1001/jama.2023.21984

This JAMA Patient Page describes oral health, particularly care of the teeth and prevention of tooth and gum disease, and discusses the pros and cons of screening for dental caries by primary care clinicians.

Podcast: USPSTF Recommendations: Screening and Preventive Interventions for Oral Health in Adults and in Children and Adolescents Aged 5 to 17 Years

Editorial
A Call for More Oral Health Research in Primary Care
Michael S. Reddy, DMD, DMSc; Rena N. D鈥橲ouza, DDS, MS, PhD; Jennifer Webster-Cyriaque, DDS, PhD

JAMA
- Podcast: USPSTF Recommendations: Screening and Preventive Interventions for Oral Health in Adults and in Children and Adolescents Aged 5 to 17 Years

Comment & Response

Review of Diabetic Foot Ulcers

Michael B. Strauss, MD; Katherine Wilson, BS

Abstract Full Text

JAMA. 2023;330(17):1694-1695. doi:10.1001/jama.2023.17197

Review of Diabetic Foot Ulcers

Weili Feng, MD; Xiaoping Wang, MD

Abstract Full Text

JAMA. 2023;330(17):1695. doi:10.1001/jama.2023.17191

Review of Diabetic Foot Ulcers鈥擱eply

David G. Armstrong, DPM, MD, PhD; Andrew J. M. Boulton, MD; Sicco A. Bus, PhD

Abstract Full Text

JAMA. 2023;330(17):1695-1696. doi:10.1001/jama.2023.17194

Bempedoic Acid for Primary Prevention of Cardiovascular Events

Mark R. Goldstein, MD; Luca Mascitelli, MD

Abstract Full Text

JAMA. 2023;330(17):1696. doi:10.1001/jama.2023.17335

Bempedoic Acid for Primary Prevention of Cardiovascular Events鈥擱eply

Steven E. Nissen, MD; Stephen J. Nicholls, MBBS, PhD; A. Michael Lincoff, MD

Abstract Full Text

JAMA. 2023;330(17):1696-1697. doi:10.1001/jama.2023.17341

Correction

Incorrect Study Data

Abstract Full Text

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JAMA. 2023;330(17):1697. doi:10.1001/jama.2023.19045

November 2024 - July 1883

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November 7, 2023, Vol 330, No. 17, Pages 1601-1703

Caring for the Critically Ill Patient

Recommendation Statement

Evidence Report

AI in Medicine

AI in Medicine

Climate Change and Health

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