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November 2024 - July 1883

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March 28, 2023, Vol 329, No. 12, Pages 961-1040

This Week in JAMA

Audio Highlights

Abstract Full Text
free access online only has audio
JAMA. 2023;329(12):e2215845. doi:10.1001/jama.2022.15845
  • Podcast: Tight Glycemic Control and Use of Verapamil in Pediatric Type 1 Diabetes, US Trends in Pediatric Mental Health Hospitalizations, Evaluation for Secondary Hypertension in Children, and more
Original Investigation

Effect of Tight Glycemic Control on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes: A Randomized Clinical Trial

Jennifer McVean, MD; Gregory P. Forlenza, MD; Roy W. Beck, MD, PhD; et al.
Abstract Full Text
free access
JAMA. 2023;329(12):980-989. doi:10.1001/jama.2023.2063

This randomized clinical trial compares the efficacy of intensive glucose management, which included use of an automated insulin delivery system, vs standard care, which included use of a continuous glucose monitor, to achieve near normalization of glucose levels to preserve pancreatic beta cell function in youths with newly diagnosed type 1 diabetes.

Effect of Verapamil on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes: A Randomized Clinical Trial

Gregory P. Forlenza, MD; Jennifer McVean, MD; Roy W. Beck, MD, PhD; et al.
Abstract Full Text
free access
JAMA. 2023;329(12):990-999. doi:10.1001/jama.2023.2064

This randomized clinical trial compares the effect of verapamil on pancreatic beta cell function vs placebo in children and adolescents with newly diagnosed type 1 diabetes.

Pediatric Mental Health Hospitalizations at Acute Care Hospitals in the US, 2009-2019

Mary Arakelyan, MPH; Seneca Freyleue, MS; Divya Avula, MPH; et al.
Abstract Full Text
free access has audio
JAMA. 2023;329(12):1000-1011. doi:10.1001/jama.2023.1992

This retrospective analysis of a nationally representative database of US acute care hospital discharges assesses increased mental health diagnoses and hospitalizations among pediatric patients between 2009 and 2019.

  • Podcast: Trends in Pediatric Mental Health Hospitalizations
Research Letter

Discontinuation of Conventional Synthetic Disease-Modifying Antirheumatic Drugs in Patients With Rheumatoid Arthritis and Excellent Disease Control

Siri Lillegraven, MD, MPH, PhD; Nina Paulshus Sundlisæter, MD, PhD; Anna-Birgitte Aga, MD, PhD; et al.
Abstract Full Text
free access
JAMA. 2023;329(12):1024-1026. doi:10.1001/jama.2023.0492

This open-label randomized clinical trial assessed the 12-month risk of disease activity flares after discontinuation of conventional synthetic DMARDs (csDMARDs) compared with continuing half-dose csDMARDs in adult Norwegian patients with rheumatoid arthritis and excellent disease control.

Trends in Dietary Vitamin A Intake Among US Adults by Race and Ethnicity, 2003-2018

Ting-Yuan David Cheng, PhD; Carrollyn Ferderber; Benjamin Kinder, MPH; et al.
Abstract Full Text
free access
JAMA. 2023;329(12):1026-1029. doi:10.1001/jama.2023.0636

This study uses data from the 2003-2004 to 2017-2018 National Health and Nutrition Examination Surveys (NHANES) to assess whether a difference exists in dietary vitamin A intake as a marker of consumption of vitamin A鈥搑ich foods among Black, Hispanic, and White adults in the US.

Viewpoint

The Uncertain Future of the Determination of Brain Death

Robert D. Truog, MD, MA
Abstract Full Text
has audio
JAMA. 2023;329(12):971-972. doi:10.1001/jama.2023.1472

This Viewpoint discusses the proposals that have been considered in the process of the Uniform Law Commission assessing whether the Uniform Determination of Death Act should be revised and offers pros and cons of each.

  • Podcast: The Uncertain Future of the Determination of Brain Death

Attacks on Health Care Used as a Weapon of War in Ukraine and Globally: The Demand for Accountability

Michele Heisler, MD, MPA; Pavlo Kovtonyuk, MHA; Christian De Vos, JD, PHD
Abstract Full Text
JAMA. 2023;329(12):973-974. doi:10.1001/jama.2023.2787

In this Viewpoint, authors from Physicians for Human Rights and the Ukrainian Healthcare Center present findings from a joint report documenting the attacks on health care workers and facilities as a weapon of war in the Russian war with Ukraine.

The New Crisis of Increasing All-Cause Mortality in US Children and Adolescents

Steven H. Woolf, MD, MPH; Elizabeth R. Wolf, MD, MPH; Frederick P. Rivara, MD, MPH
Abstract Full Text
JAMA. 2023;329(12):975-976. doi:10.1001/jama.2023.3517

This Viewpoint discusses increased rates in pediatric mortality by age and cause between 1999 and 2021.

A Piece of My Mind

Virtually Grounded

Jonathan Zygowiec, DO, MPH, MA
Abstract Full Text
JAMA. 2023;329(12):977. doi:10.1001/jama.2023.1803

In this narrative essay, an emergency medicine physician who is undergoing treatment for stage IV colorectal cancer discusses the role that virtual reality might play in end-of-life care in the future to help patients virtually travel the world and connect with others.

Editorial

Preserving Pancreatic Beta Cell Function in Recent-Onset Type 1 Diabetes

Jennifer Couper, MD
Abstract Full Text
JAMA. 2023;329(12):978-979. doi:10.1001/jama.2023.2140
The Rational Clinical Examination

Does This Child With High Blood Pressure Have Secondary Hypertension?The Rational Clinical Examination Systematic Review

James T. Nugent, MD, MPH; Kuan Jiang, BS; Melissa C. Funaro, MS, MLS; et al.
Abstract Full Text
has active quiz has audio
JAMA. 2023;329(12):1012-1021. doi:10.1001/jama.2023.3184

This systematic review assesses the utility of history, physical examination, and 24-hour ambulatory blood pressure monitoring for differentiating primary hypertension from secondary hypertension in children and adolescents younger than 21 years of age.

  • Podcast: Does This Child With High Blood Pressure Have Secondary Hypertension? With Dr Nugent
JAMA Insights

Women's Health

Comprehensive Management of Type 2 Diabetes During Pregnancy

Amy M. Valent, DO, MCR; Aaron B. Caughey, MD, MPH, PhD
Abstract Full Text
has active quiz
JAMA. 2023;329(12):1022-1023. doi:10.1001/jama.2023.0929

This JAMA Insights Clinical Update discusses a comprehensive approach to treating pregnant patients with type 2 diabetes to reduce adverse perinatal and neonatal outcomes.

Editor's Note

Illness Metaphors and COVID-19

Rafael Campo, MA, MD
Abstract Full Text
free access
JAMA. 2023;329(12):1035. doi:10.1001/jama.2023.1507
Medical News & Perspectives

Highlights From CROI, the Conference on Retroviruses and Opportunistic Infections鈥擯ostexposure Prophylaxis for Sexually Transmitted Infections, a New Protease Inhibitor for COVID-19, Goals for Preventing HIV Transmission, and More

Rita Rubin, MA
Abstract Full Text
has audio
JAMA. 2023;329(12):963-964. doi:10.1001/jama.2023.0158

This Medical News Q&A discusses research highlights from the recent Conference on Retroviruses and Opportunistic Infections.

  • Podcast: Live From CROI, the Conference on Retroviruses and Opportunistic Infections

Groundswell Grows for Permanent Daylight Saving Time, but Medical Societies Overwhelmingly Support Year-Round Standard Time

Rita Rubin, MA
Abstract Full Text
has audio
JAMA. 2023;329(12):965-967. doi:10.1001/jama.2023.0159

This Medical News feature examines the possible health consequences of making daylight saving time permanent.

  • Podcast: March 2023 Medical News Summary
Medical News in Brief

Severe Form of Mpox Identified in Patients With Advanced HIV

Emily Harris
Abstract Full Text
free access
JAMA. 2023;329(12):968. doi:10.1001/jama.2023.3191

FDA Approves First Over-the-counter Combined COVID-19 and Flu Test

Emily Harris
Abstract Full Text
free access
JAMA. 2023;329(12):968. doi:10.1001/jama.2023.3192

Ultrasound Treatment Improved Parkinson Disease Symptoms

Emily Harris
Abstract Full Text
free access
JAMA. 2023;329(12):968. doi:10.1001/jama.2023.3193

Autoimmunity in Down Syndrome Linked to Immune System Dysregulation

Emily Harris
Abstract Full Text
free access
JAMA. 2023;329(12):968. doi:10.1001/jama.2023.3194

CDC Report Documents Disparities in Mental Health鈥揜elated ED Visits

Emily Harris
Abstract Full Text
free access
JAMA. 2023;329(12):968. doi:10.1001/jama.2023.3195

Blood Biomarker Helps Distinguish Vascular Dementia

Emily Harris
Abstract Full Text
free access
JAMA. 2023;329(12):969. doi:10.1001/jama.2023.3196

Older Black Men Have Higher Mortality After Elective Surgery

Emily Harris
Abstract Full Text
free access
JAMA. 2023;329(12):969. doi:10.1001/jama.2023.3197

WHO: Marburg Virus Outbreak Confirmed in Equatorial Guinea

Emily Harris
Abstract Full Text
free access
JAMA. 2023;329(12):969. doi:10.1001/jama.2023.3199

Fewer MRIs to Monitor Small Incidental Pituitary Tumors Might Be Safe

Emily Harris
Abstract Full Text
free access
JAMA. 2023;329(12):969. doi:10.1001/jama.2023.3200
Poetry and Medicine

Spiked Cetus

Richard Donze, DO, MPH
Abstract Full Text
JAMA. 2023;329(12):1035. doi:10.1001/jama.2023.1572
JAMA Revisited

The Problem of Preventive Medicine: In Practice and in Medical Education

Abstract Full Text
JAMA. 2023;329(12):1036. doi:10.1001/jama.2022.15846
JAMA Patient Page

What Is Lead Poisoning?

Kristin Walter, MD, MS
Abstract Full Text
free access
JAMA. 2023;329(12):1040. doi:10.1001/jama.2023.1543

This JAMA Patient Page describes lead poisoning, its health effects, diagnosis, treatment, and prevention measures.

Comment & Response

Selective Decontamination of the Digestive Tract and Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation

Nicolas Massart, MD; Pierre Fillatre, MD; Christophe Camus, MD, PhD
Abstract Full Text
JAMA. 2023;329(12):1029. doi:10.1001/jama.2023.0221

Selective Decontamination of the Digestive Tract and Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation

Rogier M. Determann, MD, PhD; Nicole P. Juffermans, MD, PhD; Peter H. J. van der Voort, MD, PhD
Abstract Full Text
JAMA. 2023;329(12):1029-1030. doi:10.1001/jama.2023.0218

Selective Decontamination of the Digestive Tract and Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation鈥擱eply

John A. Myburgh, MD, PhD; Ian M. Seppelt, MD; Simon R. Finfer, MD; et al.
Abstract Full Text
JAMA. 2023;329(12):1030-1031. doi:10.1001/jama.2023.0215

Human Mpox Virus Infection After Receipt of Modified Vaccinia Ankara Vaccine

Ya Bin Zhou, MD, PhD
Abstract Full Text
JAMA. 2023;329(12):1031. doi:10.1001/jama.2023.0447

Human Mpox Virus Infection After Receipt of Modified Vaccinia Ankara Vaccine鈥擱eply

Aniruddha Hazra, MD; John A. Schneider, MD, MPH
Abstract Full Text
JAMA. 2023;329(12):1032. doi:10.1001/jama.2023.0450

Extended Follow-up of Microbiome Therapeutic SER-109 for Recurrent Clostridioides difficile Infection

Fergus Hamilton, MBChB; William F. Wright, DO, MPH; Todd C. Lee, MD, MPH
Abstract Full Text
JAMA. 2023;329(12):1032-1033. doi:10.1001/jama.2023.0497

Extended Follow-up of Microbiome Therapeutic SER-109 for Recurrent Clostridioides difficile 滨苍蹿别肠迟颈辞苍鈥搁别辫濒测

Stuart H. Cohen, MD; Thomas J. Louie, MD; Barbara H. McGovern, MD
Abstract Full Text
JAMA. 2023;329(12):1033-1034. doi:10.1001/jama.2023.0496
Correction

Incorrect Data in Abstract and Figure

Abstract Full Text
free access
JAMA. 2023;329(12):1034. doi:10.1001/jama.2023.3272
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2023;329(12):961-962. doi:10.1001/jama.2022.15844

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