August 6, 2014 Issue of JAMA

August 6, 2014, Vol 312, No. 5, Pages 459-562

This Week in JAMA

Highlights

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JAMA. 2014;312(5):459-461. doi:10.1001/jama.2013.279641

Podcast: Screening and interventions for problem drug use in primary care, nutrition in the ICU, diagnosis of bladder outlet obstruction, and more.

Original Investigation

Brief Intervention for Problem Drug Use in Safety-Net Primary Care Settings: A Randomized Clinical Trial

Peter Roy-Byrne, MD; Kristin Bumgardner, BS; Antoinette Krupski, PhD; et al.

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JAMA. 2014;312(5):492-501. doi:10.1001/jama.2014.7860

Editorial
Screening and Brief Intervention and Referral to Treatment for Drug Use in Primary Care: Back to the Drawing Board
Ralph Hingson, ScD, MPH; Wilson M. Compton, MD, MPE

JAMA

Screening and Brief Intervention for Drug Use in Primary Care: The ASPIRE Randomized Clinical Trial

Richard Saitz, MD, MPH; Tibor P. A. Palfai, PhD; Debbie M. Cheng, ScD; et al.

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JAMA. 2014;312(5):502-513. doi:10.1001/jama.2014.7862

Saitz and coauthors tested the efficacy of 2 brief interventions among 528 adults with unhealthy drug use identified by screening in primary care. They compared a brief negotiated interview and an intervention based on motivational interviewing with no brief intervention. In an Editorial, Hingson and Compton discuss the importance of exploring drug use with patients in primary care.

Podcast: Screening and Brief Intervention for Drug Use in Primary Care

Editorial
Screening and Brief Intervention and Referral to Treatment for Drug Use in Primary Care: Back to the Drawing Board
Ralph Hingson, ScD, MPH; Wilson M. Compton, MD, MPE

JAMA

Caring for the Critically Ill Patient

High-Protein Enteral Nutrition Enriched With Immune-Modulating Nutrients vs Standard High-Protein Enteral Nutrition and Nosocomial Infections in the ICU: A Randomized Clinical Trial

Arthur R. H. van Zanten, MD, PhD; François Sztark, MD, PhD; Udo X. Kaisers, MD, PhD; et al.

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JAMA. 2014;312(5):514-524. doi:10.1001/jama.2014.7698

van Zanten and coauthors found that critically ill patients breathing with the aid of ventilation in intensive care units did not experience improvement in infectious complications when receiving immune-modulating nutrients compared with standard high-protein enteral nutrition.

Editorial
Immunonutrition in Critical Illness: Limited Benefit, Potential Harm
Todd W. Rice, MD, MSc

JAMA

Genetic Variants Associated With Phenytoin-Related Severe Cutaneous Adverse Reactions

Wen-Hung Chung, MD, PhD; Wan-Chun Chang, MS; Yun-Shien Lee, PhD; et al.

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JAMA. 2014;312(5):525-534. doi:10.1001/jama.2014.7859

Chung and coauthors conducted a case-control study in populations from Taiwan, Japan, and Malaysia and a genome-wide association study to investigate the genetic factors associated with phenytoin-related severe cutaneous adverse reactions.

Research Letter

Association of Long vs Standard Detection Intervals for Implantable Cardioverter-Defibrillators With Hospitalizations and Costs

Alessandro Proclemer, MD; Angel Arenal, MD; Maurizio Lunati, MD; et al.

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JAMA. 2014;312(5):555-557. doi:10.1001/jama.2014.4783

Viewpoint

Health Care at the VA: Recommendations for Change

Faisal G. Bakaeen, MD; Alvin Blaustein, MD; Melina R. Kibbe, MD

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JAMA. 2014;312(5):481-482. doi:10.1001/jama.2014.8054

Podcast: JAMA: 2014-08-05, Vol. 312, No. 5, Author Reading

Assessing Value in Biomedical Research: The PQRST of Appraisal and Reward

John P. A. Ioannidis, MD, DSc; Muin J. Khoury, MD, PhD

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JAMA. 2014;312(5):483-484. doi:10.1001/jama.2014.6932

The Global Slowdown in Health Care Spending Growth

David Squires, MA

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JAMA. 2014;312(5):485-486. doi:10.1001/jama.2014.7221

A Piece of My Mind

You

Ali Mendelson, MD

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JAMA. 2014;312(5):487. doi:10.1001/jama.2014.7236

Editorial

Screening and Brief Intervention and Referral to Treatment for Drug Use in Primary Care: Back to the Drawing Board

Ralph Hingson, ScD, MPH; Wilson M. Compton, MD, MPE

Abstract Full Text

JAMA. 2014;312(5):488-489. doi:10.1001/jama.2014.7863

Immunonutrition in Critical Illness: Limited Benefit, Potential Harm

Todd W. Rice, MD, MSc

Abstract Full Text

JAMA. 2014;312(5):490-491. doi:10.1001/jama.2014.7699

The Rational Clinical Examination

Does This Man With Lower Urinary Tract Symptoms Have Bladder Outlet Obstruction?The Rational Clinical Examination: A Systematic Review

Karen A. D鈥橲ilva, MD, MS; Philipp Dahm, MD, MHSc; Camilla L. Wong, MD, MHSc

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JAMA. 2014;312(5):535-542. doi:10.1001/jama.2014.5555

D鈥橲ilva and coauthors assess the diagnostic accuracy of symptoms, questionnaires, and studies in the diagnosis of bladder outlet obstruction.

Podcast: Does This Man With Lower Urinary Tract Symptoms Have Bladder Outlet Obstruction? The Rational Clinical Examination: A Systematic Review

JAMA Guide to Statistics and Methods

Multiple Comparison Procedures

Jing Cao, PhD; Song Zhang, PhD

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JAMA. 2014;312(5):543-544. doi:10.1001/jama.2014.9440

Podcast: JAMA Guide to Statistics and Methods
JAMAevidence: Guide to Statistics and Methods: Multiple Comparison Procedures from the JAMA Guide to Statistics and Methods
Podcast: A Simple Way to Understand Statistical Multiple Comparison Procedures

From the 糖心vlog

Peer Victimization, Cyberbullying, and Suicide Risk in Children and Adolescents

Gianluca Gini, PhD; Dorothy L. Espelage, PhD

Abstract Full Text

JAMA. 2014;312(5):545-546. doi:10.1001/jama.2014.3212

JAMA Clinical Challenge

Malar Rash in a Stem Cell Transplant Recipient

Matthew Mansh, BS; Weilan Johnson, MD; Jennifer Lai, MD

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JAMA. 2014;312(5):547-548. doi:10.1001/jama.2014.1370

Medical News & Perspectives

Research on Psychiatric Disorders Targets Inflammation

M. J. Friedrich

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JAMA. 2014;312(5):474-476. doi:10.1001/jama.2014.8276

Largest-Ever Ebola Outbreak Still Simmering in West Africa

Joan Stephenson, PhD

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JAMA. 2014;312(5):476. doi:10.1001/jama.2014.9757

News From the Centers for Disease Control and Prevention

news@JAMA

News From JAMA鈥檚 Daily News Site

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JAMA. 2014;312(5):476. doi:10.1001/jama.2014.9186

Lab Reports

Immune Molecules Affect Tuberculosis Outcomes

Tracy Hampton, PhD

Abstract Full Text

JAMA. 2014;312(5):477. doi:10.1001/jama.2014.9185

Statins鈥� Link to Diabetes Risk Revealed

Tracy Hampton, PhD

Abstract Full Text

JAMA. 2014;312(5):477. doi:10.1001/jama.2014.9731

Small Molecule Treats Heart Arrhythmias in Fish

Tracy Hampton, PhD

Abstract Full Text

JAMA. 2014;312(5):477. doi:10.1001/jama.2014.9732

HIV Integration Sites Linked to Viral Persistence

Tracy Hampton, PhD

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JAMA. 2014;312(5):477. doi:10.1001/jama.2014.9733

The Art of JAMA

Fire-Swept, Algoma: Franz Johnston

Thomas B. Cole, MD, MPH

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JAMA. 2014;312(5):466-467. doi:10.1001/jama.2013.279643

Poetry and Medicine

Gift

Terry S. Johnson

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JAMA. 2014;312(5):561. doi:10.1001/jama.2014.4652

JAMA Revisited

The Prostate Gland: A Review of its Anatomy, Pathology, and Treatment

A. H. Wilson, M.D., M.R.C.S.

Abstract Full Text

JAMA. 2014;312(5):562. doi:10.1001/jama.2013.279650

Comment & Response

Age-Adjusted D-Dimer Cutoff Levels and Pulmonary Embolism

Giorgio Colombo, MS; Ludovico Furlan, MD; Giulia Colombo, MS

Abstract Full Text

JAMA. 2014;312(5):557. doi:10.1001/jama.2014.7604

Age-Adjusted D-Dimer Cutoff Levels and Pulmonary Embolism鈥擱eply

Marc Righini, MD; Pieter W. Kamphuisen, MD, PhD; Grégoire Le Gal, MD, PhD

Abstract Full Text

JAMA. 2014;312(5):557. doi:10.1001/jama.2014.7607

Potential Conflicts of Interest for Academic Medical Center Leaders

John C. Lechleiter, PhD

Abstract Full Text

JAMA. 2014;312(5):558. doi:10.1001/jama.2014.7563

Potential Conflicts of Interest for Academic Medical Center Leaders

Arnold S. Relman, MD

Abstract Full Text

JAMA. 2014;312(5):558. doi:10.1001/jama.2014.7569

Potential Conflicts of Interest for Academic Medical Center Leaders鈥擱eply

Timothy S. Anderson, MD; Chester B. Good, MD, MPH; Walid F. Gellad, MD, MPH

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JAMA. 2014;312(5):558-559. doi:10.1001/jama.2014.7578

Ending the Sale of Cigarettes at US Pharmacies

Frederieke S. van der Deen, BSc, MSc; Amber L. Pearson, MSc, MPH, PhD; Nick Wilson, MBChB, DIH, MPH

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JAMA. 2014;312(5):559. doi:10.1001/jama.2014.7560

Ending the Sale of Cigarettes at US Pharmacies

Victor O. Kolade, MD, MS

Abstract Full Text

JAMA. 2014;312(5):559-560. doi:10.1001/jama.2014.7566

Ending the Sale of Cigarettes at US Pharmacies鈥擱eply

Troyen A. Brennan, MD, MPH; Steven Schroeder, MD

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JAMA. 2014;312(5):560. doi:10.1001/jama.2014.7572

Correction

Incorrect Word in Comment Section

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JAMA. 2014;312(5):560. doi:10.1001/jama.2014.9370

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August 6, 2014, Vol 312, No. 5, Pages 459-562

Caring for the Critically Ill Patient

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