January 15, 2014 Issue of JAMA

糖心vlog

January 15, 2014, Vol 311, No. 3, Pages 217-321

This Week in JAMA

Highlights

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JAMA. 2014;311(3):217-219. doi:10.1001/jama.2013.279276

Podcast: Varespladib for ACS, surveillance CEA measures and CT to prevent CRC recurrence, review of management of sigmoid diverticulitis, and more.

Original Investigation

Varespladib and Cardiovascular Events in Patients With an Acute Coronary Syndrome: The VISTA-16 Randomized Clinical Trial

Stephen J. Nicholls, MBBS, PhD; John J. P. Kastelein, MD, PhD; Gregory G. Schwartz, MD, PhD; et al.

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JAMA. 2014;311(3):252-262. doi:10.1001/jama.2013.282836

To determine the effects of secretory phospholipase A₂ inhibition with varespladib on cardiovascular outcomes, Nicholls and coauthors randomized 5145 patients within 96 hours of presentation of an acute coronary syndrome to either varspladib (n鈥�=鈥�2572) or placebo (n鈥�=鈥�2573) for 16 weeks.

Effect of 3 to 5 Years of Scheduled CEA and CT Follow-up to Detect Recurrence of Colorectal Cancer: The FACS Randomized Clinical Trial

John N. Primrose, MD, FRCS; Rafael Perera, DPhil; Alastair Gray, BA, PhD; et al.

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JAMA. 2014;311(3):263-270. doi:10.1001/jama.2013.285718

Primrose and coauthors conducted a randomized clinical trial among 1202 patients at 39 hospitals in England to assess the effectiveness of blood measurement of carcinoembryonic antigen (CEA) and computed tomography (CT) as follow-up to detect recurrent colorectal cancer treatable with curative intent.

Podcast: Effect of 3 to 5 Years of Scheduled CEA and CT Follow-up to Detect Recurrence of Colorectal Cancer: The FACS Randomized Clinical Trial

Calcium Density of Coronary Artery Plaque and Risk of Incident Cardiovascular Events

Michael H. Criqui, MD, MPH; Julie O. Denenberg, MA; Joachim H. Ix, MD, MAS; et al.

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JAMA. 2014;311(3):271-278. doi:10.1001/jama.2013.282535

In a multicenter, prospective, observational trial at 6 US sites, Criqui and colleagues study a diverse cohort of 3398 men and women, aged 45 to 84 years, to determine the independent associations of coronary artery calcium (CAC) volume and CAC density with incident cardiovascular disease events. In a related Editorial, Greenland discusses more evidence for CAC as a measure of cardiovascular risk.

Podcast: Calcium Density of Coronary Artery Plaque and Risk of Incident Cardiovascular Events

Editorial
More Evidence for Coronary Calcium as a Measure of Cardiovascular Risk: Has Anything Changed?
Philip Greenland, MD

JAMA

Prevalence of Vascular Complications Among Patients With Glucokinase Mutations and Prolonged, Mild Hyperglycemia

Anna M. Steele, PhD; Beverley M. Shields, PhD; Kirsty J. Wensley, AdDip(Nursing); et al.

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JAMA. 2014;311(3):279-286. doi:10.1001/jama.2013.283980

Steele and coauthors assess the association between chronic mild hyperglycemia and complication prevalence and severity among 271 participants in the United Kingdom.

Editorial
Insights From Monogenic Diabetes and Glycemic Treatment Goals for Common Types of Diabetes
Jose C. Florez, MD, PhD

JAMA

Research Letter

One-Year Follow-up of Intracoronary Stem Cell Delivery on Left Ventricular Function Following ST-Elevation Myocardial Infarction

Jay H. Traverse, MD; Timothy D. Henry, MD; Carl J. Pepine, MD; et al.

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JAMA. 2014;311(3):301-302. doi:10.1001/jama.2013.282674

Viewpoint

Sports-Related Concussions in Youth: Report From the Institute of Medicine and National Research Council

Frederick P. Rivara, MD, MPH; Robert Graham, MD

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JAMA. 2014;311(3):239-240. doi:10.1001/jama.2013.282985

Podcast: JAMA: 2014-01-14, Vol. 311, No. 3, Author Reading

Implications of New Insurance Coverage for Access to Care, Cost-Sharing, and Reimbursement

A. Everette James III, JD; Walid F. Gellad, MD; Brian A. Primack, MD

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JAMA. 2014;311(3):241-242. doi:10.1001/jama.2013.283150

Extending Simulation Learning Experiences to Patients With Chronic Health Conditions

Eric A. Coleman, MD, MPH

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JAMA. 2014;311(3):243-244. doi:10.1001/jama.2013.283057

A Piece of My Mind

The Mask

Rachel R. Osborn, MD

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JAMA. 2014;311(3):245-246. doi:10.1001/jama.2013.284778

Editorial

More Evidence for Coronary Calcium as a Measure of Cardiovascular Risk: Has Anything Changed?

Philip Greenland, MD

Abstract Full Text

JAMA. 2014;311(3):247-248. doi:10.1001/jama.2013.282536

Insights From Monogenic Diabetes and Glycemic Treatment Goals for Common Types of Diabetes

Jose C. Florez, MD, PhD

Abstract Full Text

JAMA. 2014;311(3):249-251. doi:10.1001/jama.2013.283981

Review

Sigmoid Diverticulitis: A Systematic Review

Arden M. Morris, MD, MPH; Scott E. Regenbogen, MD, MPH; Karin M. Hardiman, MD, PhD; et al.

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JAMA. 2014;311(3):287-297. doi:10.1001/jama.2013.282025

After analyzing 80 articles, Morris and coauthors report that recent studies demonstrat a lesser role for aggressive antibiotic or surgical intervention for recurrent or chronic diverticulitis.

From the 糖心vlog

Alzheimer Gene APOE 蔚4 Linked to Brain Development in Infants

Jessica Mc Donald, PhD; Dimitri Krainc, MD, PhD

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JAMA. 2014;311(3):298-299. doi:10.1001/jama.2013.285400

Medical News & Perspectives

Researchers Probe the Aging Brain in Health and Disease

M. J. Friedrich

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JAMA. 2014;311(3):231-232. doi:10.1001/jama.2013.284609

Another Novel Oral Anticoagulant Matches Warfarin

Mike Mitka, MSJ

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JAMA. 2014;311(3):233-234. doi:10.1001/jama.2013.284833

FDA Pushes Makers of Antimicrobial Soap to Prove Safety and Effectiveness

Bridget M. Kuehn, MSJ

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JAMA. 2014;311(3):234. doi:10.1001/jama.2013.285971

News From the Centers for Disease Control and Prevention

US Malaria Cases Reach 40-Year High

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JAMA. 2014;311(3):236. doi:10.1001/jama.2013.285271

Teen Smokers Turn to Flavored Cigars

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JAMA. 2014;311(3):236. doi:10.1001/jama.2013.285274

Global Health

2009 Influenza Pandemic鈥檚 Death Rate Higher Than Previously Reported

M. J. Friedrich

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JAMA. 2014;311(3):235. doi:10.1001/jama.2013.285364

Reduced Dose of Primaquine Effective in Blocking Malaria Transmission

M. J. Friedrich

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JAMA. 2014;311(3):235. doi:10.1001/jama.2013.285742

Overregulation of Opioid Analgesics

M. J. Friedrich

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JAMA. 2014;311(3):235. doi:10.1001/jama.2013.285813

HIV Cases Are Increasing in Eastern Europe and Central Asia

M. J. Friedrich

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JAMA. 2014;311(3):235. doi:10.1001/jama.2013.285814

news@JAMA

From JAMA鈥檚 Daily News Site

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JAMA. 2014;311(3):234. doi:10.1001/jama.2013.285703

The Art of JAMA

Flower Still Life: Maria van Oosterwijck

Jeanette M. Smith, MD

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JAMA. 2014;311(3):228-229. doi:10.1001/jama.2013.279278

Poetry and Medicine

Home Visit

Donna Pucciani

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JAMA. 2014;311(3):307. doi:10.1001/jama.2013.133754

JAMA Revisited

鈥淐ure鈥� of Rheumatism and Joint-Trouble

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JAMA. 2014;311(3):313. doi:10.1001/jama.2013.279285

JAMA Patient Page

Oral Contraceptives

Jill Jin, MD, MPH

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JAMA. 2014;311(3):321. doi:10.1001/jama.2013.283505

Comment & Response

Financial Incentives to Control Hypertension in Patients

David C. Norris, MD

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JAMA. 2014;311(3):303. doi:10.1001/jama.2013.284312

Financial Incentives to Control Hypertension in Patients鈥擱eply

Laura A. Petersen, MD, MPH; LeChauncy D. Woodard, MD, MPH; Tracy H. Urech, MPH

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JAMA. 2014;311(3):303-304. doi:10.1001/jama.2013.284315

Physician Payment Incentives to Improve Care Quality

David U. Himmelstein, MD; Steffie Woolhandler, MD, MPH

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JAMA. 2014;311(3):304. doi:10.1001/jama.2013.284475

Physician Payment Incentives to Improve Care Quality鈥擱eply

Naomi S. Bardach, MD, MAS; Sarah C. Shih, MPH; R. Adams Dudley, MD, MBA

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JAMA. 2014;311(3):304. doi:10.1001/jama.2013.284478

Formulation of Treatment Recommendations for Statins

Cait O鈥橲ullivan, PharmD, BScPh, BA; Linda Brown, BScPharm, MSc

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JAMA. 2014;311(3):305. doi:10.1001/jama.2013.284440

Formulation of Treatment Recommendations for Statins

Mark D. Huffman, MD, MPH; Shah Ebrahim, BM, BS, MSc, DM; Kay Dickersin, PhD

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JAMA. 2014;311(3):305-306. doi:10.1001/jama.2013.284443

Formulation of Treatment Recommendations for Statins鈥擱eply

Paul M Ridker, MD, MPH; Peter W. F. Wilson, MD

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JAMA. 2014;311(3):306. doi:10.1001/jama.2013.284481

Correction

Incorrect Language

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JAMA. 2014;311(3):306. doi:10.1001/jama.2013.283704

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January 15, 2014, Vol 311, No. 3, Pages 217-321

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