Marc Righini, MD; Josien Van Es, MD, PhD; Paul L. Den Exter, MD; et al.
Righini and coauthors prospectively validate among 3346 patients in Belgium, France, the Netherlands, and Switzerland whether an age-adjusted D-dimer cut-off, defined as age × 10 in patients aged 50 years or older, can safely increase the diagnostic yield of D-dimer in elderly patients with suspected pulmonary embolism.