Jojo Y. Y. Kwok, PhD, MPH, BN, RN; Jackie C. Y. Kwan, MSocSc, PDMH, BSW, RSW; M. Auyeung, MBChB; et al.
free access
JAMA Neurol. 2019;76(7):755-763. doi:10.1001/jamaneurol.2019.0534
This randomized clinical trial compares the effects of mindfulness yoga vs conventional stretching and resistance training exercise on anxiety and depression in adults with idiopathic Parkinson disease in Hong Kong.
Jeff S. Healey, MD; David J. Gladstone, MD; Balakumar Swaminathan, MSc; et al.
free access
JAMA Neurol. 2019;76(7):764-773. doi:10.1001/jamaneurol.2019.0617
This secondary analysis of a randomized clinical trial investigates whether rivaroxaban is associated with a reduction in recurrent stroke among patients with embolic stroke of undetermined source who have an increased risk of atrial fibrillation.
Holly Tillman, MS; S. Claiborne Johnston, MD, PhD; Mary Farrant, MBA; et al.
free access
has audio
JAMA Neurol. 2019;76(7):774-782. doi:10.1001/jamaneurol.2019.0932
This secondary analysis of a randomized clinical trial examines the short-term risk of hemorrhage in treating patients in North America, Europe, and Australasia with acute transient ischemic attack or minor acute ischemic stroke with clopidogrel plus aspirin or aspirin alone.
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Podcast:
Risk for Major Hemorrhages in Patients Receiving Clopidogrel and Aspirin Compared With Aspirin Alone
Hyunmi Kim, MD, PhD, MPH; Edward Faught, MD; David J. Thurman, MD, MPH; et al.
free access
JAMA Neurol. 2019;76(7):783-790. doi:10.1001/jamaneurol.2019.0447
This cohort study examines the use of antiepileptic drugs and differences between valproate and topiramate prescribing in women of childbearing age with epilepsy.
Niklas Mattsson, MD, PhD; Nicholas C. Cullen, BSc; Ulf Andreasson, PhD; et al.
free access
JAMA Neurol. 2019;76(7):791-799. doi:10.1001/jamaneurol.2019.0765
This cohort study uses data from the Alzheimer’s Disease Neuroimaging Initiative study to examine whether plasma neurofilament light, a noninvasive biomarker measurement, is associated with other markers of Alzheimer disease and other measures of neurodegeneration in patients with Alzheimer disease.
Vasileios Kokkinos, PhD; Nathaniel D. Sisterson, BA; Thomas A. Wozny, MD; et al.
free access
JAMA Neurol. 2019;76(7):800-808. doi:10.1001/jamaneurol.2019.0658
This review of electrocorticographic recordings and clinical meta-data assesses seizure control in 12 patients with focal epilepsy who were treated with closed-loop invasive brain stimulation.
Thomas S. Wingo, MD; David J. Cutler, PhD; Aliza P. Wingo, MD, MSc; et al.
free access
JAMA Neurol. 2019;76(7):809-817. doi:10.1001/jamaneurol.2019.0648
This case series study investigates the association between circulating cholesterol levels and early-onset Alzheimer disease and identifies genetic variants underlying any possible association in blood samples of patients with early-onset Alzheimer disease.
Lei Yu, PhD; Vladislav A. Petyuk, PhD; Shinya Tasaki, PhD; et al.
free access
JAMA Neurol. 2019;76(7):818-826. doi:10.1001/jamaneurol.2019.0834
This cohort study combines long-standing community-based samples to examine the associations between cortical β-amyloid protein in the absence of insoluble deposits with cognitive decline, neurofibrillary tangles, other age-associated neuropathologic signs and symptoms, and APOE.
Daniel Morales, PhD; Alexandra Pacurariu, PhD; Jim Slattery, MSc; et al.
free access
JAMA Neurol. 2019;76(7):827-833. doi:10.1001/jamaneurol.2019.0887
This nested case-control study uses a large primary care population database in the United Kingdom to analyze the relative and absolute risk estimates of peripheral neuropathy among adults issued prescriptions for oral fluoroquinolone or amoxicillin-clavulanate antibiotics.
Marie Deen, MD; Anders Hougaard, PhD; Hanne Demant Hansen, PhD; et al.
free access
JAMA Neurol. 2019;76(7):834-840. doi:10.1001/jamaneurol.2019.0755
This study examines the mechanism by which triptan drugs enter the central nervous system in individuals with migraine.
Christiane Gasperi, MD; Anke Salmen, MD; Gisela Antony, DiplPsych; et al.
free access
JAMA Neurol. 2019;76(7):841-849. doi:10.1001/jamaneurol.2019.0905
This cohort study of patients with relapsing-remitting multiple sclerosis or clinically isolated syndrome assessed a possible association of intrathecal IgG synthesis and Expanded Disability Status Scale scores in the 4 years after diagnosis.