Romain Bourcier, MD; Mayank Goyal, MD; David S. Liebeskind, MD; et al.
free access
JAMA Neurol. 2019;76(4):405-411. doi:10.1001/jamaneurol.2018.4510
This meta-analysis of individual patient data from 7 randomized clinical trials analyzes the rate of reperfusion after endovascular thrombectomy started at different intervals after symptom onset in patients with acute ischemic stroke.
Jessica K. Lee, PhD; Vincent Koppelmans, PhD; Roy F. Riascos, PhD; et al.
free access
JAMA Neurol. 2019;76(4):412-419. doi:10.1001/jamaneurol.2018.4882
This study maps spaceflight-induced intracranial extracellular free water (FW) shifts and evaluates changes in brain white matter diffusion measures in astronauts following spaceflight.
Dilan Athauda, MRCP, PhD; Seema Gulyani, PhD; Hanuma kumar Karnati, PhD; et al.
free access
JAMA Neurol. 2019;76(4):420-429. doi:10.1001/jamaneurol.2018.4304
This secondary analysis of the Exenatide-PD trial assesses whether patients with Parkinson disease have augmented activity in brain insulin and protein kinase B signaling pathways.
Sarah Song, MD, MPH; Li Liang, PhD; Gregg C. Fonarow, MD; et al.
free access
JAMA Neurol. 2019;76(4):430-439. doi:10.1001/jamaneurol.2018.4410
This analysis compares the characteristics, care, and outcomes of Asian American and white patients with acute ischemic stroke at hospitals participating in the Get With The Guidelines–Stroke program.
Colin B. Josephson, MD, MSc, FRCPC; Jordan D. T. Engbers, PhD; Nathalie Jette, MD, MSc; et al.
free access
JAMA Neurol. 2019;76(4):440-446. doi:10.1001/jamaneurol.2018.4561
This open cohort study derives prediction models to estimate the risk of psychiatric adverse effects from levetiracetam use in patients with epilepsy.
Maarten G. Lansberg, MD, PhD; Michael Mlynash, MD; Scott Hamilton, PhD; et al.
free access
JAMA Neurol. 2019;76(4):447-453. doi:10.1001/jamaneurol.2018.4587
This secondary analysis of a randomized clinical trial determines the association of thrombectomy among patients by age, symptom severity, time to randomization, arterial occlusive lesion location, and imaging modality.
Gustaf Brander, MSc; Kayoko Isomura, MD, PhD; Zheng Chang, PhD; et al.
free access
JAMA Neurol. 2019;76(4):454-461. doi:10.1001/jamaneurol.2018.4279
This longitudinal population-based cohort study investigates the risk of metabolic and cardiovascular disorders among individuals with Tourette syndrome or chronic tic disorder over a period of 40 years.
John P. Andrews, MD; Abhijeet Gummadavelli, MD; Pue Farooque, DO; et al.
free access
JAMA Neurol. 2019;76(4):462-469. doi:10.1001/jamaneurol.2018.4316
This cohort study examines the association of seizure spread with seizure recurrence after surgery in patients who underwent medial temporal resections for drug-resistant temporal lobe epilepsy.
Eduardo De Pablo-Fernández, MD; Andrew J. Lees, MD; Janice L. Holton, MD, PhD; et al.
free access
JAMA Neurol. 2019;76(4):470-479. doi:10.1001/jamaneurol.2018.4377
This study provides longitudinal clinical disease-course data and neuropathologic association for newly proposed Parkinson disease subtypes.
Sandro Marini, MD; Katherine Crawford, BS; Andrea Morotti, MD; et al.
open access
JAMA Neurol. 2019;76(4):480-491. doi:10.1001/jamaneurol.2018.4519
This case-control study examines whether the risk for intracerebral hemorrhage presented by apolipoprotein E ε4 and ε2 alleles varies by race/ethnicity.