Amrou Sarraj, MD; Ameer E. Hassan, DO; Sean Savitz, MD; et al.
free access
JAMA Neurol. 2019;76(10):1147-1156. doi:10.1001/jamaneurol.2019.2109
This prespecified secondary analysis of a cohort study compares outcomes in patients with large ischemic cores treated with endovascular thrombectomy vs medical management alone.
Brenda Huppke, MD; David Ellenberger, MSc; Hannah Hummel, MD; et al.
free access
JAMA Neurol. 2019;76(10):1157-1165. doi:10.1001/jamaneurol.2019.1997
This study examines whether high body mass index in children and adolescents is a factor in the onset of multiple sclerosis and in treatment response.
Elan L. Guterman, MD; I. Elaine Allen, PhD; S. Andrew Josephson, MD; et al.
free access
JAMA Neurol. 2019;76(10):1166-1173. doi:10.1001/jamaneurol.2019.1820
This cohort study uses data from the Care Ecosystem study to investigate whether caregiver depression is associated with increased use of the emergency department among patients with dementia.
Clifford R. Jack Jr, MD; Terry M. Therneau, PhD; Stephen D. Weigand, MS; et al.
open access
JAMA Neurol. 2019;76(10):1174-1183. doi:10.1001/jamaneurol.2019.1971
This population-based cohort study estimates the sex- and age-specific prevalence of 3 imaging biomarker鈥揵ased definitions of the Alzheimer disease spectrum from the National Institute on Aging鈥揂lzheimer鈥檚 Association research framework and compares these entities with clinically defined diagnostic entities commonly linked with Alzheimer disease.
Hui Xu, MSc; Rongrong Yang, MSc; Xiuying Qi, PhD; et al.
free access
JAMA Neurol. 2019;76(10):1184-1191. doi:10.1001/jamaneurol.2019.2455
This cohort study examines the association of lifespan cognitive reserve with dementia risk.
Ying Xian, MD, PhD; Haolin Xu, MS; Emily C. O鈥橞rien, PhD; et al.
free access
has audio
JAMA Neurol. 2019;76(10):1192-1202. doi:10.1001/jamaneurol.2019.2099
This cohort assesses the clinical effectiveness of direct oral anticoagulants vs warfarin for stroke prevention in patients with atrial fibrillation.
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Podcast:
Clinical Effectiveness of Direct Oral Anticoagulants vs Warfarin in Older Patients With Atrial Fibrillation and Ischemic Stroke
Jennifer S. Rabin, PhD; Hannah Klein, BSc; Dylan R. Kirn, MPH; et al.
free access
JAMA Neurol. 2019;76(10):1203-1210. doi:10.1001/jamaneurol.2019.1879
This study examines whether physical activity moderates the association of 尾-amyloid burden with longitudinal cognitive decline and neurodegeneration in clinically normal individuals.
Olajide Williams, MD, MS; Jeanne Teresi, EdD, PhD; Joseph P. Eimicke, MS; et al.
free access
has multimedia
JAMA Neurol. 2019;76(10):1211-1218. doi:10.1001/jamaneurol.2019.1741
This cluster randomized clinical trial of stroke preparedness among black and Hispanic churchgoers evaluates the effect of culturally tailored 12-minute stroke films on stroke preparedness vs the usual care practice of distributing stroke education pamphlets.
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Video:
Excerpt From
Derrame Cerebral, a Video Telenovella To Educate Hispanic Churchgoers About Stroke Warning Signs
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Video:
Excerpt From
Gospel of Stroke, a Music Video To Educate Black Churchgoers About Stroke Warning Signs
Christopher H. van Dyck, MD; Haakon B. Nygaard, MD, PhD; Kewei Chen, PhD; et al.
open access
JAMA Neurol. 2019;76(10):1219-1229. doi:10.1001/jamaneurol.2019.2050
This randomized clinical trial examines the effects, safety, and tolerability of AZD0530 medication in patients with mild Alzheimer disease.
Marian Galovic, MD; Victor Q. H. van Dooren, MSc; Tjardo S. Postma, MD; et al.
free access
JAMA Neurol. 2019;76(10):1230-1239. doi:10.1001/jamaneurol.2019.1708
This case-control study examines whether progressive cortical thinning in patients with focal epilepsy is distinct from cortical thinning associated with normal aging.