ÌÇÐÄvlog

This cross-sectional study investigates association of white matter rarefaction and cerebrovascular disease with dementia in deceased men older than 40 years who had played football and been found to have chronic traumatic encephalopathy.

This randomized clinical trial tests the hypothesis that targeting intensive blood pressure lowering of systolic and diastolic blood pressure less than 120 mm Hg and less than 80 mm Hg, respectively, reduces the rate of stroke recurrence compared with a standard blood pressure–lowering regimen.

This multicenter longitudinal cohort study of 741 participants uses in vivo β-amyloid cerebrospinal fluid and positron emission tomography findings to track progression of Alzheimer disease across 6 years of follow-up.

This phase 2 randomized clinical trial assesses the efficacy, safety, and tolerability of edonerpic maleate for patients with mild to moderate Alzheimer disease.

This case-control study examines neuronal-enriched extracellular vesicles as predictors of Alzheimer disease.

This cohort study examines the association between the level of care received by Canadian patients with epilepsy and the risk of premature mortality.

This cohort study compares changes in serum levels of neurofilament light chains with progression of disease among patients with multiple sclerosis.

This population-based parent-offspring heritability study examines the extent of amyotrophic lateral sclerosis heritability and assesses the association of sex with disease transmission

This study analyzes the decades-long early progression of Huntington disease and its dependence on CAG repeat length.