J. David Spence, MD; Catherine M. Viscoli, PhD; Silvio E. Inzucchi, MD; et al.
free access
JAMA Neurol. 2019;76(5):526-535. doi:10.1001/jamaneurol.2019.0079
This post hoc analysis of Insulin Resistance Intervention After Stroke (IRIS) randomized clinical trial assesses the association of pioglitazone vs placebo with recurrent stroke, myocardial infarction, and other cardiovascular events.
Katharine Harding, PhD; Owain Williams, MBBCh; Mark Willis, PhD; et al.
free access
JAMA Neurol. 2019;76(5):536-541. doi:10.1001/jamaneurol.2018.4905
This cohort study analyzes long-term outcomes in a patients with multiple sclerosis according to initial treatment strategy.
Rachel F. Buckley, PhD; Elizabeth C. Mormino, PhD; Jennifer S. Rabin, PhD; et al.
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JAMA Neurol. 2019;76(5):542-551. doi:10.1001/jamaneurol.2018.4693
This analysis of 2 cross-sectional cohort studies examines the sex differences in the association between 尾-amyloid and regional tau deposition as measured with positron emission tomography (PET).
Yuesong Pan, PhD; Weiqi Chen, MD, PhD; Yilong Wang, MD, PhD; et al.
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JAMA Neurol. 2019;76(5):552-560. doi:10.1001/jamaneurol.2018.4775
This secondary analysis of the Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events (CHANCE) randomized clinical trial investigates the association of ABCB1 polymorphisms with efficacy of clopidogrel plus aspirin vs aspirin alone in patients with minor stroke or transient ischemic attack.
Marian Galovic, MD; Anne Julia Stauber, MD; Natascha Leisi, MSc; et al.
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JAMA Neurol. 2019;76(5):561-570. doi:10.1001/jamaneurol.2018.4858
This validation study describes the development of a prognostic model to predict swallowing recovery and guide the decision for enteral tube feeding in people with dysphagia after ischemic stroke.
Hermann Neugebauer, MD, MSc; Hauke Schneider, MD, MBA; Julian Bösel, MD; et al.
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JAMA Neurol. 2019;76(5):571-579. doi:10.1001/jamaneurol.2018.4822
This randomized clinical trial assesses whether moderate hypothermia after early hemicraniectomy reduces mortality in patients with malignant MCA stroke, compared with standard treatment.
Tomas Dobrocky, MD; Lorenz Grunder, MD; Philipe S. Breiding, MD; et al.
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JAMA Neurol. 2019;76(5):580-587. doi:10.1001/jamaneurol.2018.4921
This case-control study assesses brain magnetic resonance imaging data to develop a probability score of cerebrospinal fluid leak in patients with spontaneous intracranial hypotension.
Nima Etminan, MD; Han-Sol Chang, MD; Katharina Hackenberg, MD; et al.
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JAMA Neurol. 2019;76(5):588-597. doi:10.1001/jamaneurol.2019.0006
This systematic review and meta-analysis assesses worldwide aneurysmal subarachnoid hemorrhage incidence according to region, age, sex, time period, blood pressure, and smoking prevalence.
Matthew P. Pase, PhD; Alexa S. Beiser, PhD; Jayandra J. Himali, PhD; et al.
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JAMA Neurol. 2019;76(5):598-606. doi:10.1001/jamaneurol.2018.4666
This cohort study assesses the association between plasma total tau level and later development of dementia by comparing laboratory, clinical, and autopsy data from participants in the Framingham Heart Study in the United States and the Memento Study in France.