Ajay Malhotra, MD, MMM; Xiao Wu, BS; Howard P. Forman, MD, MBA; et al.
free access
JAMA Neurol. 2018;75(1):27-34. doi:10.1001/jamaneurol.2017.3232
This comparative effectiveness analysis evaluates the effectiveness of routine treatment (aneurysm coiling) vs 3 different strategies for imaging surveillance compared with no preventive treatment or routine follow-up of tiny unruptured intracranial aneurysms.
Paolo Zamboni, MD; Luigi Tesio, MD; Stefania Galimberti, PhD; et al.
open access
JAMA Neurol. 2018;75(1):35-43. doi:10.1001/jamaneurol.2017.3825
This randomized clinical trial determines the efficacy and safety of venous percutaneous transluminal angioplasty in patients with multiple sclerosis with chronic cerebrospinal venous insufficiency.
Jessica Mozersky, PhD; Pamela Sankar, PhD; Kristin Harkins, MPH; et al.
free access
JAMA Neurol. 2018;75(1):44-50. doi:10.1001/jamaneurol.2017.2954
This study examines comprehension of an elevated amyloid positron emission tomographic biomarker result by cognitively unimpaired older adults to inform the processes of describing Alzheimer disease biomarkers to cognitively normal adults and assessing their understanding of this knowledge.
Fadar Oliver Otite, MD, ScM; Priyank Khandelwal, MD; Amer M. Malik, MD, MBA; et al.
free access
JAMA Neurol. 2018;75(1):51-57. doi:10.1001/jamaneurol.2017.3496
This population-based study compares the use of coronary artery stenting in elderly patients between the years before and after publication of the Carotid Revascularization Endarterectomy vs Stenting Trial (CREST).
Jinsy A. Andrews, MD; Lisa Meng, PhD; Sarah F. Kulke, MD; et al.
open access
JAMA Neurol. 2018;75(1):58-64. doi:10.1001/jamaneurol.2017.3339
This study investigates the rate of decline in percentage predicted slow vital capacity and its association with respiratory-related clinical events and mortality in patients with amyotrophic lateral sclerosis.
Shahd H. M. Hamid, MBBS, MRCP; Dan Whittam, BMBS, MRCP; Mariyam Saviour, MBChB, BSc; et al.
free access
JAMA Neurol. 2018;75(1):65-71. doi:10.1001/jamaneurol.2017.3196
The case series describes myelin oligodendrocyte glycoprotein IgG鈥� and aquaporin 4 IgG鈥揳ssociated disease in 134 English patients who presented with seizure.
Ryan Sanford, MEng; Lesley K. Fellows, MD, CM, DPhil; Beau M. Ances, MD, PhD; et al.
free access
JAMA Neurol. 2018;75(1):72-79. doi:10.1001/jamaneurol.2017.3036
This longitudinal case-control study examines whether detectable brain changes occur during a 2-year period in HIV-positive individuals who were aviremic and treated with combination antiretroviral therapy.
Woo-Jin Lee, MD; Keun-Hwa Jung, MD, PhD; Young Jin Ryu, MD; et al.
free access
JAMA Neurol. 2018;75(1):80-87. doi:10.1001/jamaneurol.2017.2853
This study investigates the association between chronically altered cardiac hemodynamics and the severity of cerebral white matter hyperintensity in patients with chronic valvular heart disease.
Yujing Zhao, BA; Dana L. Tudorascu, PhD; Oscar L. Lopez, MD; et al.
free access
JAMA Neurol. 2018;75(1):88-96. doi:10.1001/jamaneurol.2017.3029
This longitudinal study in a subgroup of the Ginkgo Evaluation of Memory study compares the patterns of long-term cognitive decline in multiple domains by preclinical biomarker status in the oldest old without dementia.
Galit Weinstein, PhD; Shira Zelber-Sagi, PhD; Sarah R. Preis, ScD, MPH; et al.
free access
JAMA Neurol. 2018;75(1):97-104. doi:10.1001/jamaneurol.2017.3229
This cross-sectional analysis among participants from the Offspring cohort of the Framingham Study assesses the association between prevalent nonalcoholic fatty liver disease and brain magnetic resonance imaging measures.
Majida Charif, PhD; Alessia Nasca, MSc; Kyle Thompson, PhD; et al.
free access
JAMA Neurol. 2018;75(1):105-113. doi:10.1001/jamaneurol.2017.2065
This case series describes the RTN4IP1 mutations found in 12 children and young adults with severe central nervous system diseases and describes the association of these mutations with neurologic phenotypes.