Donald A. Redelmeier, MD, MSHSR; Fizza Manzoor, BHSc; Deva Thiruchelvam, MSc
free access
has audio
JAMA Neurol. 2019;76(8):887-896. doi:10.1001/jamaneurol.2019.1148
This large extended population-based double cohort study tests whether statin use is associated with an increased or decreased risk of subsequent dementia after a concussion among older adults.
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Podcast:
Association Between Statin Use and Risk of Dementia After a Concussion
Aidan Neligan, MSc, PhD, MRCP; Alastair John Noyce, MSc, PhD, MRCP; Tushar Divakar Gosavi, MD, MRCP; et al.
free access
JAMA Neurol. 2019;76(8):897-905. doi:10.1001/jamaneurol.2019.1268
This systematic review and meta-analysis examines the change in convulsive status epilepticus–associated mortality among studies of adults and children in 17 countries..
Wen-Yi Huang, MD, PhD; Jeffrey L. Saver, MD; Yi-Ling Wu, DrPH; et al.
free access
JAMA Neurol. 2019;76(8):906-914. doi:10.1001/jamaneurol.2019.1120
This systematic review and meta-analysis assesses the risk of intracranial hemorrhage associated with low-dose aspirin among individuals without symptomatic cardiovascular disease.
Bernard J. Hanseeuw, MD; Rebecca A. Betensky, PhD; Heidi I. L. Jacobs, PhD; et al.
open access
JAMA Neurol. 2019;76(8):915-924. doi:10.1001/jamaneurol.2019.1424
This cohort study assesses the associations among amyloid-β, tau, and cognition, measured during different observation periods for 7 years.
Eric E. Smith, MD, MPH; Jiming Fang, PhD; Shabbir M. Alibhai, MD, MSc, FRCPC; et al.
free access
JAMA Neurol. 2019;76(8):925-931. doi:10.1001/jamaneurol.2019.1114
This prognostic study evaluated medical records of survivors of ischemic stroke from a national Canadian database to develop and validate a scoring system to predict low-trauma fractures within 1 year of hospital discharge.
M. Julia Machline-Carrion, MD, MHS, PhD; Eliana Vieira Santucci, BSc; Lucas Petri Damiani, MSc; et al.
free access
JAMA Neurol. 2019;76(8):932-941. doi:10.1001/jamaneurol.2019.1012
This cluster randomized clinical trial assesses the effect of a multifaceted quality improvement intervention compared with routine care on adherence to evidence-based therapy among patients with acute ischemic stroke and transient ischemic attack.
Giuseppe Tosto, MD, PhD; Badri Vardarajan, PhD; Sanjeev Sariya, MS; et al.
free access
JAMA Neurol. 2019;76(8):942-948. doi:10.1001/jamaneurol.2019.1066
This gene-based transethnic meta-analysis combines data from community-based cohorts to find genetic variants associated with late-onset Alzheimer disease.
Audrey C. Leasure, BS; Adnan I. Qureshi, MD; Santosh B. Murthy, MD, MPH; et al.
free access
JAMA Neurol. 2019;76(8):949-955. doi:10.1001/jamaneurol.2019.1141
This exploratory analysis of Antihypertensive Treatment of Acute Cerebral Hemorrhage–2 randomized clinical trial data seeks to determine whether intensive blood pressure reduction is associated with decreased risk of hematoma expansion in patients with intracerebral hemorrhage and if these associations are modified by the specific deep-brain nuclei involved.
Alexander E. Merkler, MD; Sigurdur Sigurdsson, MS; Gudny Eiriksdottir, MSc; et al.
free access
JAMA Neurol. 2019;76(8):956-961. doi:10.1001/jamaneurol.2019.1226
This cross-sectional study of a cohort of the Age, Gene/Environment Susceptibility–Reykjavik Study determines whether unrecognized myocardial infarction detected by cardiac magnetic resonance imaging is associated with cerebral infarction.
Amy Y. X. Yu, MD, MSc; Andrew M. Penn, MD; Mary L. Lesperance, PhD; et al.
free access
JAMA Neurol. 2019;76(8):962-968. doi:10.1001/jamaneurol.2019.1305
This cohort study assesses whether sex differences exist in symptoms, diagnoses, or outcomes among patients presenting with acute transient or minor neurologic events at multicenter academic emergency departments in Canada.
Adam M. Staffaroni, PhD; Abigail O. Kramer, MS; Megan Casey, BS; et al.
free access
JAMA Neurol. 2019;76(8):969-977. doi:10.1001/jamaneurol.2019.1071
This longitudinal cohort study assesses whether plasma and cerebrospinal fluid biomarkers are associated with survival time in sporadic Creutzfeldt-Jakob disease.