ÌÇÐÄvlog

[Skip to Navigation]
Sign In

October 2024 - July 1959

Decade

Year

Issue

July 2022, Vol 79, No. 7, Pages 644-727

Viewpoint

Disclosing Alzheimer Disease Biomarker Results to Research Participants

Abstract Full Text
JAMA Neurol. 2022;79(7):645-646. doi:10.1001/jamaneurol.2022.1307

This Viewpoint discusses issues surrounding the release of biomarker measures by research studies to their participants.

On the Brain

When a Neurologist Gets a Cerebrospinal Fluid Leak

Abstract Full Text
JAMA Neurol. 2022;79(7):647-648. doi:10.1001/jamaneurol.2022.0863

This essay describes how a neurologist’s experience with a cerebrospinal fluid leak led to newfound gratitude for their own treating physicians and nurses and insight into patients’ experiences.

Editorial

Rare APOE Missense Variants—Can We Overcome APOE ε4 and Alzheimer Disease Risk?

Abstract Full Text
JAMA Neurol. 2022;79(7):649-651. doi:10.1001/jamaneurol.2022.0854
Original Investigation

Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease

Abstract Full Text
free access
JAMA Neurol. 2022;79(7):652-663. doi:10.1001/jamaneurol.2022.1166

This genetic association study evaluates whether rare missense variants on APOE are associated with Alzheimer disease risk.

Evaluation of Outcomes Among Patients With Traumatic Intracranial Hypertension Treated With Decompressive Craniectomy vs Standard Medical Care at 24 Months: A Secondary Analysis of the RESCUEicp Randomized Clinical Trial

Abstract Full Text
free access
JAMA Neurol. 2022;79(7):664-671. doi:10.1001/jamaneurol.2022.1070

This randomized clinical trial uses Extended Glasgow Outcome Scale scores to evaluate 24-month outcomes for patients with traumatic intracranial hypertension who received a decompressive craniectomy vs standard medical treatment.

Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability

Abstract Full Text
open access has audio
JAMA Neurol. 2022;79(7):672-681. doi:10.1001/jamaneurol.2022.1269

This cohort study evaluates whether children exposed prenatally to antiseizure medications in mono- and duotherapy have increased risk of neurodevelopmental disorders.

Association of Brain Atrophy With Disease Progression Independent of Relapse Activity in Patients With Relapsing Multiple Sclerosis

Abstract Full Text
open access
JAMA Neurol. 2022;79(7):682-692. doi:10.1001/jamaneurol.2022.1025

This cohort study examines magnetic resonance imaging scans to determine changes in regional and total brain volume among patients with relapsing multiple sclerosis who have disease progression without relapse activity.

TDP-43 Accumulation Within Intramuscular Nerve Bundles of Patients With Amyotrophic Lateral Sclerosis

Abstract Full Text
open access
JAMA Neurol. 2022;79(7):693-701. doi:10.1001/jamaneurol.2022.1113

This dual case-control and cohort study assesses for a characteristic pathological hallmark in the muscle tissues of patients with amyotrophic lateral sclerosis.

Clinical Manifestations of Early-Onset Dementia With Lewy Bodies Compared With Late-Onset Dementia With Lewy Bodies and Early-Onset Alzheimer Disease

Abstract Full Text
free access
JAMA Neurol. 2022;79(7):702-709. doi:10.1001/jamaneurol.2022.1133

This case-control study investigates clinical features that distinguish early-onset dementia with Lewy bodies from late-onset dementia with Lewy bodies and from early-onset Alzheimer disease (AD) dementia.

Association of Aortic Stiffness and Pressure Pulsatility With Global Amyloid-β and Regional Tau Burden Among Framingham Heart Study Participants Without Dementia

Abstract Full Text
free access
JAMA Neurol. 2022;79(7):710-719. doi:10.1001/jamaneurol.2022.1261

This cross-sectional study evaluates the association of aortic stiffness and pressure pulsatility with global amyloid-β and regional tau burden among middle-aged and older Framingham Heart Study Third Generation participants without dementia.

Images in Neurology

Neuronal Ceroid Lipofuscinosis Owing to Complete Maternal Uniparental Disomy

Abstract Full Text
has active quiz
JAMA Neurol. 2022;79(7):720-721. doi:10.1001/jamaneurol.2022.1008

This case report describes a woman aged 31 years who presented with light perception visual acuity, ambiguous speech, and a worsening history of tonic-clonic seizures despite treatment.

Cerebral Ultrasonography of Cytotoxic Edema in a Newborn With a Mitochondrial Disorder

Abstract Full Text
has active quiz
JAMA Neurol. 2022;79(7):722-723. doi:10.1001/jamaneurol.2022.0957

This case report describes a preterm newborn with a mitochondrial disorder and cytotoxic edema seen on cerebral ultrasonography.

JAMA Neurology Clinical Challenge

Bilateral Complete Ophthalmoplegia in a 50-Year-Old Man

Abstract Full Text
has active quiz
JAMA Neurol. 2022;79(7):724-725. doi:10.1001/jamaneurol.2022.1320

A 50-year-old man had ophthalmoplegia that developed immediately after robotic cystectomy for small cell cancer of the bladder. What is your diagnosis?

Comment & Response

Commentary on Long-term Effectiveness of Adjuvant Treatment in Parkinson Disease

Abstract Full Text
JAMA Neurol. 2022;79(7):726. doi:10.1001/jamaneurol.2022.1601

Commentary on Long-term Effectiveness of Adjuvant Treatment in Parkinson Disease—Reply

Abstract Full Text
JAMA Neurol. 2022;79(7):726-727. doi:10.1001/jamaneurol.2022.1604
Correction

Errors in Results in Abstract and Text and in Table 1

Abstract Full Text
free access
JAMA Neurol. 2022;79(7):727. doi:10.1001/jamaneurol.2022.1581

Error in Figure

Abstract Full Text
free access
JAMA Neurol. 2022;79(7):727. doi:10.1001/jamaneurol.2022.1883

Error in Text

Abstract Full Text
free access
JAMA Neurol. 2022;79(7):727. doi:10.1001/jamaneurol.2022.1964
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2022;79(7):644. doi:10.1001/jamaneurol.2021.3778
×