ÌÇÐÄvlog

This cohort study analyzes data from 4 independent cohorts to assess the clinical value of proposed biological research criteria intended to identify individuals with preclinical Alzheimer disease.

This cohort study tests a deep learning model using readily available clinical information to predict treatment success with the first antiseizure medication for individual patients.

This post hoc analysis of the Atrial Fibrillation Detected by Continuous Electrocardiogram Monitoring Using Implantable Loop Recorder to Prevent Stroke in High-Risk Individuals (LOOP) randomized clinical trial investigates if implantable loop recorder screening for atrial fibrillation can reduce the risk of severe stroke in individuals with risk factors or prior stroke history.

This randomized clinical trial investigates the efficacy and safety of partial receptor agonist vamorolone compared with placebo and prednisone in boys with Duchenne muscular dystrophy.

This post hoc analysis of the randomized clinical trial, Study of LY3002813 in Participants With Early Symptomatic Alzheimer’s Disease (TRAILBLAZER-ALZ), investigates if amyloid reduction from donanemab treatment is associated with slowing of tau pathology and clinical decline in individuals with early symptomatic Alzheimer disease.

This cohort study investigates the timing at which β-amyloid–positron emission tomography (PET) binding starts showing associations with other markers of Alzheimer disease using the Alzheimer’s Disease Neuroimaging Initiative, the Harvard Aging Brain Study, and the Presymptomatic Evaluation of Experimental or Novel Treatments for Alzheimer Disease Research Group.

This systematic review and meta-analysis compares temporal trends in incidence of stroke at younger vs older ages in high-income countries.

This systematic review and meta-analysis assesses data for adults with acute brain injury who were admitted to intensive care units to evaluate the association of neurocritical care with patient-centered outcomes.