Willemijn J. Jansen, PhD; Olin Janssen, MSc; Betty M. Tijms, PhD; et al.
free access
JAMA Neurol. 2022;79(3):228-243. doi:10.1001/jamaneurol.2021.5216
This cross-sectional study evaluates amyloid biomarkers on positron emission tomography scans and in cerebrospinal fluid in individuals with normal cognition, subjective cognitive decline, mild cognitive impairment, or clinical Alzheimer disease dementia.
Sara K. Rostanski, MD; Alexandra Kvernland, MD; Ava L. Liberman, MD; et al.
free access
has audio
JAMA Neurol. 2022;79(3):244-250. doi:10.1001/jamaneurol.2021.4905
This post hoc analysis of a randomized clinical trial investigates whether the association of clopidogrel-aspirin treatment with stroke recurrence in patients with minor stroke or high-risk transient ischemic attack is modified by the presence of infarct on imaging attributed to the index event.
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Podcast:
Infarct on Brain Imaging, Subsequent Ischemic Stroke, and Clopidogrel-Aspirin Efficacy
Nagy Mekhail, MD, PhD; Robert M. Levy, MD, PhD; Timothy R. Deer, MD; et al.
free access
JAMA Neurol. 2022;79(3):251-260. doi:10.1001/jamaneurol.2021.4998
This secondary analysis of a randomized clinical trial determines whether evoked compound action potentials鈥揷ontrolled, closed-loop spinal cord stimulator is associated with better outcomes compared with fixed-output, open-loop spinal cord stimulator at 24 months following implant.
Yen Ying Lim, PhD; Paul Maruff, PhD; Nicolas R. Barthélemy, PhD; et al.
free access
JAMA Neurol. 2022;79(3):261-270. doi:10.1001/jamaneurol.2021.5181
This cross-sectional study investigates whether site-specific tau phosphorylation occupancy is associated with BDNF Val66Met in presymptomatic and symptomatic dominantly inherited Alzheimer disease.
Silvia Koton, PhD, RN; James Russell Pike, MBA; Michelle Johansen, MD, PhD; et al.
free access
JAMA Neurol. 2022;79(3):271-280. doi:10.1001/jamaneurol.2021.5080
This cohort study evaluates the association between risk of dementia and incident ischemic stroke by stroke severity and recurrence.
Guillaume Turc, MD; Melika Hadziahmetovic, MD; Silke Walter, MD; et al.
free access
JAMA Neurol. 2022;79(3):281-290. doi:10.1001/jamaneurol.2021.5321
This systematic review and meta-analysis investigates whether mobile stroke unit use is associated with better functional outcomes in patients with acute ischemic stroke.