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October 2024 - July 1959

Decade

Year

Issue

February 2022, Vol 79, No. 2, Pages 103-199

Viewpoint

Modernizing Psychiatry Training for Neurologists—From Off-Service to In-Service

Abstract Full Text
JAMA Neurol. 2022;79(2):113-114. doi:10.1001/jamaneurol.2021.4456

This Viewpoint recommends 3 core guidelines to reconfigure psychiatry training for neurologists.

Clinical Neurophysiology Fellowships—They Can and Should Change

Abstract Full Text
JAMA Neurol. 2022;79(2):115-116. doi:10.1001/jamaneurol.2021.4763

This Viewpoint discusses why neurology residencies should offer more precise curriculum based on practice settings and Clinical Neurophysiology fellowships should be replaced by Comprehensive Ambulatory Neurology fellowships.

Editorial

Unintended Consequences of Approving Unproven Treatments—Hope, Hype, or Harm?

Abstract Full Text
JAMA Neurol. 2022;79(2):117-118. doi:10.1001/jamaneurol.2021.4193

Adjunctive Therapies in Parkinson Disease—Have We Made Meaningful Progress?

Abstract Full Text
JAMA Neurol. 2022;79(2):119-120. doi:10.1001/jamaneurol.2021.4140
Original Investigation

Safety and Effectiveness of Long-term Intravenous Administration of Edaravone for Treatment of Patients With Amyotrophic Lateral Sclerosis

Abstract Full Text
free access
JAMA Neurol. 2022;79(2):121-130. doi:10.1001/jamaneurol.2021.4893

This multicenter cohort study uses real-world clinical data to compare the long-term safety and effectiveness of intravenous edaravone plus riluzole therapy vs propensity score–matched controls receiving riluzole therapy alone among patients with amyotrophic lateral sclerosis.

Long-term Effectiveness of Adjuvant Treatment With Catechol-O-Methyltransferase or Monoamine Oxidase B Inhibitors Compared With Dopamine Agonists Among Patients With Parkinson Disease Uncontrolled by Levodopa Therapy: The PD MED Randomized Clinical Trial

Abstract Full Text
open access
JAMA Neurol. 2022;79(2):131-140. doi:10.1001/jamaneurol.2021.4736

This randomized clinical trial assesses the long-term effects on patient-rated quality of life of adjuvant treatment with dopamine reuptake inhibitors compared with dopamine agonists among patients with motor complications of Parkinson disease that are inadequately controlled by levodopa therapy.

Comparison of Ticagrelor vs Clopidogrel in Addition to Aspirin in Patients With Minor Ischemic Stroke and Transient Ischemic Attack: A Network Meta-analysis

Abstract Full Text
free access
JAMA Neurol. 2022;79(2):141-148. doi:10.1001/jamaneurol.2021.4514

This network meta-analysis compares ticagrelor and aspirin with clopidogrel and aspirin in patients with acute minor ischemic stroke or transient ischemic attack in the prevention of recurrent strokes or death.

Biomarker-Based Prediction of Longitudinal Tau Positron Emission Tomography in Alzheimer Disease

Abstract Full Text
open access
JAMA Neurol. 2022;79(2):149-158. doi:10.1001/jamaneurol.2021.4654

This cohort study describes longitudinal tau positron emission tomography findings using [18F]RO948 across the different clinical stages of Alzheimer disease.

Assessment of Erenumab Safety and Efficacy in Patients With Migraine With and Without Aura: A Secondary Analysis of Randomized Clinical Trials

Abstract Full Text
open access has active quiz has audio
JAMA Neurol. 2022;79(2):159-168. doi:10.1001/jamaneurol.2021.4678

This post hoc secondary analysis of 4 randomized clinical trials evaluates changes in migraine frequency, medication use, and patient-reported outcomes associated with erenumab use.

Association Between Antiseizure Drug Monotherapy and Mortality for Patients With Poststroke Epilepsy

Abstract Full Text
free access has active quiz
JAMA Neurol. 2022;79(2):169-175. doi:10.1001/jamaneurol.2021.4584

This cohort study uses data from linked registers in Sweden to investigate whether mortality varies with specific antiseizure medications among patients with poststroke epilepsy.

Comparison of Drug-Eluting Stent With Bare-Metal Stent in Patients With Symptomatic High-grade Intracranial Atherosclerotic Stenosis: A Randomized Clinical Trial

Abstract Full Text
free access
JAMA Neurol. 2022;79(2):176-184. doi:10.1001/jamaneurol.2021.4804

This randomized clinical trial evaluates the rate of in-stent restenosis and the risk of stroke recurrence after the placement of a drug-eluting stent vs standard bare-metal stent among patients with symptomatic high-grade intracranial atherosclerotic stenosis.

Association of Essential Tremor With Novel Risk Loci: A Genome-Wide Association Study and Meta-analysis

Abstract Full Text
open access
JAMA Neurol. 2022;79(2):185-193. doi:10.1001/jamaneurol.2021.4781

This genome-wide association study identifies common variants associated with risk of essential tremor.

Images in Neurology

Tap-Elicited Clonus of the Biceps and Triceps Brachii

Abstract Full Text
has multimedia
JAMA Neurol. 2022;79(2):194. doi:10.1001/jamaneurol.2021.4273

This case report describes a man with an unusual manifestation of primary lateral sclerosis.

Leptomeningeal Enhancement Associated With Cerebral Venous Thrombosis

Abstract Full Text
JAMA Neurol. 2022;79(2):195-196. doi:10.1001/jamaneurol.2021.4359

This case report describes a 13-year-old girl with chronic immune thrombocytopenia, an occlusive thrombus in the anterior superior sagittal sinus, a nonocclusive thrombus in the left transverse sinus, and bifrontal pachymeningeal dural thickening and enhancement as well as bifrontal leptomeningeal enhancement.

Isolated Myoclonus of the Vocal Folds in Alexander Disease

Abstract Full Text
has multimedia
JAMA Neurol. 2022;79(2):197. doi:10.1001/jamaneurol.2021.4707

This case report describes a 45-year-old woman with chronic progressive orthostatic intolerance and dysarthria and bilateral myoclonus of the vocal folds without simultaneous movement of the soft palate.

JAMA Neurology Clinical Challenge

A Woman With Eosinophilic Brainstem Meningoencephalitis

Abstract Full Text
has active quiz
JAMA Neurol. 2022;79(2):198-199. doi:10.1001/jamaneurol.2021.4861

A 25-year-old woman presented with headache, dysarthria, double vision, and dizziness for 1 week. She had traveled to northeastern Brazil 2 months before the onset of the neurological symptoms. What is your diagnosis?

JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2022;79(2):103. doi:10.1001/jamaneurol.2021.3753
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