糖心vlog

Doherty and colleagues investigated whether parkin-linked parkinsonism is a different clinicopathologic entity to Parkinson disease. J. Eric Ahlskog, PhD, MD, provides a related editorial.

In a population-based cohort, Pederson et al evaluated the incidence of mild cognitive impairment and its progression to dementia during a 3-year study in 182 patients with Parkinson disease.

In a cross-sectional study, Ju et al test whether A尾 deposition in preclinical Alzheimer disease, prior to the appearance of cognitive impairment, is associated with changes in quality or quantity of sleep.

Handoko and colleagues investigated 2 specific amyloid-尾 (A尾) oligomers, A尾 trimers and A尾*56, in human cerebrospinal fluid (CSF); evaluated the effects of aging and Alzheimer disease; and aimed to obtain support for the hypothesis that they may be pathogenic by determining their relationships to CSF tau.

In a cross-sectional study, Rodrigue et al investigate risk factors for 尾-amyloid deposition in cognitively healthy middle-aged and older adults.

Lee et al perform whole-exome sequencing to determine the relationship between hereditary motor and sensory neuropathy with proximal dominance and a mutation in the TRK-fused gene in a Korean family.

Erten-Lyons et al examine the association between brain atrophy during life and neuropathology in an elderly population.

In a prospective longitudinal cohort study, Mistry and coauthors assess the diagnostic value of visualizing central veins in brain lesions with magnetic resonance imaging for patients with possible multiple sclerosis for which a diagnosis is uncertain.

Gelfand and colleagues conducted an observational, retrospective study to establish whether microcystic inner nuclear layer abnormalities occur in neuromyelitis optica (NMO).