糖心vlog

Naci and Owen test whether selective auditory attention can be used to detect conscious awareness and communicate with behaviorally nonresponsive patients.

Wang et al performed a cross-sectional cohort study to assess the relationship between default mode network integrity and cerebrospinal fluid biomarkers of Alzheimer disease pathology. Resting-state functional connectivity magnetic resonance imaging measures were obtained in 207 cognitively normal older individuals. See also the Editorial by Jagust.

To correlate baseline resting-state measures within the salience network and changes in behavior among patients with frontotemporal dementia, Day et al obtained functional magnetic resonance imaging data and longitudinal clinical measures from 15 prospectively accrued patients with clinically diagnosed frontotemporal dementia during 8 weeks.

In a retrospective analysis of 3 patient cohorts, Muehlschlegel and coauthors identify predictors that can distinguish reversible cerebral vasoconstriction syndrome with subarachnoid hemorrhage (SAH) from aneurysmal SAH and cryptogenic 鈥渁ngiogram-negative鈥� SAH at the time of clinical presentation.

Ghani et al test the hypothesis that the late-onset Alzheimer disease (AD) in a Caribbean Hispanic population might be explained in part by the homozygosity of unknown loci that could harbor recessive AD risk haplotypes or pathologic mutations.

In a combined genome-wide association analysis, Moskvina and coauthors assess the genetic overlap between Parkinson disease (PD) and Alzheimer disease (AD) by testing for the presence of potentially pleiotropic loci in 2 recent genome-wide association studies of PD and AD.

Kang et al evaluate the baseline characteristics and relationship to clinical features of cerebrospinal fluid biomarkers (尾-amyloid 1-42 [A尾1-42], total tau [T-tau], tau phosphorylated at threonine 181 [P-tau₁₈₁], and 伪-synuclein) in drug-naive patients with early Parkinson disease (PD) and demographically matched healthy controls enrolled in the Parkinson鈥檚 Progression Markers Initiative study.

Gaspard et al describe an electroencephalography pattern, lateralized rhythmic delta activity, encountered in critically ill subjects and determine its clinical significance in this setting.

Noreau et al evaluated the prevalence of SYNE1 mutations in individuals with mild pure cerebellar ataxia and cerebellar atrophy by sequencing the gene in a cohort of 19 French-Canadians and 21 individuals from other ethnic backgrounds.