Valeria De Giuli, MD; Mario Grassi, PhD; Corrado Lodigiani, MD, PhD; et al.
free access
JAMA Neurol. 2017;74(5):512-518. doi:10.1001/jamaneurol.2016.5704
This cohort study examines the association between migraine and ischemic stroke due to cervical artery dissection in young patients with ischemic stroke.
Bela R. Turk; Benjamin E. Theisen; Christina L. Nemeth, PhD; et al.
free access
JAMA Neurol. 2017;74(5):519-524. doi:10.1001/jamaneurol.2016.5715
This study identifies variations in the levels of antioxidant capacity and superoxide dismutase activity between adrenoleukodystrophy phenotypes in patients with cerebral adrenoleukodystrophy or adrenomyeloneuropathy, heterozygote female carriers, and healthy controls and correlates antioxidant levels with clinical outcome scores to determine a possible predictive value.
Alessandra Gaiani, MD; Ilaria Martinelli, MD; Luca Bello, MD, PhD; et al.
free access
JAMA Neurol. 2017;74(5):525-532. doi:10.1001/jamaneurol.2016.5398
This study assesses the ability of neurofilament light chain to serve as a diagnostic biomarker in amyotrophic lateral sclerosis and the prognostic value of cerebrospinal fluid neurofilament light chain in patients with amyotrophic lateral sclerosis.
Colin B. Josephson, MD; Mark Lowerison, MSc; Isabelle Vallerand, PhD; et al.
free access
JAMA Neurol. 2017;74(5):533-539. doi:10.1001/jamaneurol.2016.5042
This study reports on the effect of depression on the risk of epilepsy and seizure outcomes.
Jing Qian, PhD; Bradley T. Hyman, MD, PhD; Rebecca A. Betensky, PhD
free access
JAMA Neurol. 2017;74(5):540-548. doi:10.1001/jamaneurol.2016.5953
This study evaluates neurofibrillary tangle burden in the presence of moderate or frequent plaques and its ability to predict clinical rate of Alzheimer diesase progression.
Gaspard Gerschenfeld, MD, MSc; Ioan-Paul Muresan, MD; Raphael Blanc, MD, MSc; et al.
free access
JAMA Neurol. 2017;74(5):549-556. doi:10.1001/jamaneurol.2016.5823
This study compares the functional independence at 3 months between patients treated for acute ischemic stroke under the drip-and-ship paradigm and those treated on site (mothership paradigm).
Niklas Mattsson, MD, PhD; Ulf Andreasson, PhD; Henrik Zetterberg, MD, PhD; et al.
open access
JAMA Neurol. 2017;74(5):557-566. doi:10.1001/jamaneurol.2016.6117
This case-control study compares patients with mild cognitive impairment, patients with AD dementia, and cognitively healthy patients to test whether plasma neurofilament light concentrations are increased in patients with AD and associated with cognitive decline, other AD biomarkers, and imaging evidence of neurodegeneration.
Richard J. Kryscio, PhD; Erin L. Abner, PhD; Allison Caban-Holt, PhD; et al.
free access
JAMA Neurol. 2017;74(5):567-573. doi:10.1001/jamaneurol.2016.5778
This study aims to determine if antioxidant supplements (vitamin E or selenium) used alone or in combination can prevent dementia in asymptomatic older men.
Ethan Meltzer, MD; Peter V. Sguigna, MD; Adnan Subei, DO; et al.
free access
has multimedia
JAMA Neurol. 2017;74(5):574-582. doi:10.1001/jamaneurol.2016.5131
This case-control study assesses the association of melanopsin-mediated pupillary responses to blue and red light stimuli with abnormalities in retinal architecture in patients with multiple sclerosis.
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Video:
Melanopsin-Mediated Pupillary Constriction and Retina Abnormalities in Multiple Sclerosis
Juho Joutsa, MD, PhD; Juha O. Rinne, MD, PhD; Bruce Hermann, PhD; et al.
free access
JAMA Neurol. 2017;74(5):583-590. doi:10.1001/jamaneurol.2016.6091
This population-based case-control study examines the accumulation of amyloid in adults with childhood-onset epilepsy compared with a group of matched controls.