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October 2024 - July 1959

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April 2017, Vol 74, No. 4, Pages 375-489

In This Issue of JAMA Neurology

Highlights

Abstract Full Text
free access
JAMA Neurol. 2017;74(4):375. doi:10.1001/jamaneurol.2016.3989
Viewpoint

Hypertension—A Global Neurological Problem

Abstract Full Text
JAMA Neurol. 2017;74(4):381-382. doi:10.1001/jamaneurol.2016.4718

This Viewpoint discusses the gap in hypertension and stroke care between low-income countries and high-income countries and the role neurologists should play in stroke-prevention efforts.

Editorial

A Year in Review

Abstract Full Text
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JAMA Neurol. 2017;74(4):383. doi:10.1001/jamaneurol.2016.6004

Antibody Prevalence in Epilepsy (APE) Score—Evolution in Autoimmune Epilepsy Practice

Abstract Full Text
JAMA Neurol. 2017;74(4):384-385. doi:10.1001/jamaneurol.2016.5479

Cerebral Cortical Microinfarcts on 3-T Magnetic Resonance Imaging: A New Tool in the Study of Cerebrovascular Ischemia

Abstract Full Text
JAMA Neurol. 2017;74(4):385-386. doi:10.1001/jamaneurol.2016.5555

Circadian Rhythms and Chronotherapeutics—Underappreciated Approach to Improving Sleep and Wakefulness in Parkinson Disease

Abstract Full Text
JAMA Neurol. 2017;74(4):387-388. doi:10.1001/jamaneurol.2016.5519

Stroke Etiologic Classification—Moving From Prediction to Precision

Abstract Full Text
JAMA Neurol. 2017;74(4):388-390. doi:10.1001/jamaneurol.2016.5926

Tau and Cortical Thickness in Alzheimer Disease

Abstract Full Text
JAMA Neurol. 2017;74(4):390-392. doi:10.1001/jamaneurol.2016.5701

Selection of Patients With Multiple Sclerosis to Undergo Autologous Hematopoietic Stem Cell Transplantation

Abstract Full Text
JAMA Neurol. 2017;74(4):392-394. doi:10.1001/jamaneurol.2016.5925

Screening for Improvement of Health Outcomes in Asymptomatic Obstructive Sleep Apnea

Abstract Full Text
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JAMA Neurol. 2017;74(4):394-396. doi:10.1001/jamaneurol.2016.5975
Original Investigation

Neurological Autoantibody Prevalence in Epilepsy of Unknown Etiology

Abstract Full Text
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JAMA Neurol. 2017;74(4):397-402. doi:10.1001/jamaneurol.2016.5429

This study examines the neurological autoantibodies in patients with new-onset epilepsy and unexplained epilepsy.

Association Between Subclinical Cardiac Biomarkers and Clinically Manifest Cardiac Diseases With Cortical Cerebral Microinfarcts

Abstract Full Text
free access
JAMA Neurol. 2017;74(4):403-410. doi:10.1001/jamaneurol.2016.5335

This study examines the association of blood biomarkers of subclinical cardiac disease and clinically manifest cardiac diseases with cortical cerebral microinfarcts graded on 3-T magnetic resonance imaging in a memory clinic population.

Timed Light Therapy for Sleep and Daytime Sleepiness Associated With Parkinson Disease: A Randomized Clinical Trial

Abstract Full Text
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JAMA Neurol. 2017;74(4):411-418. doi:10.1001/jamaneurol.2016.5192

This randomized clinical trial reports the improvements in sleep-wake cycles, alertness, and motor and nonmotor functions achieved with the use of light therapy by participants with Parkinson disease.

Assessment of the Predictive Validity of Etiologic Stroke Classification

Abstract Full Text
free access
JAMA Neurol. 2017;74(4):419-426. doi:10.1001/jamaneurol.2016.5815

This study examines whether etiologic stroke subtyping using 3 different classification systems identifies different disease processes that can be recognized through their different clinical courses.

Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease

Abstract Full Text
free access
JAMA Neurol. 2017;74(4):427-436. doi:10.1001/jamaneurol.2016.5755

This case series examines whether topographical distribution and severity of hyperphosphorylated tau pathologic findings measured by [18F]AV-1451 positron emission tomographic imaging are linked with clinical phenotype and cortical atrophy in patients with Alzheimer disease.

Distribution and Quantity of Sites of John Cunningham Virus Persistence in Immunologically Healthy Patients: Correlation With John Cunningham Virus Antibody and Urine John Cunningham Virus DNA

Abstract Full Text
free access
JAMA Neurol. 2017;74(4):437-444. doi:10.1001/jamaneurol.2016.5537

This retrospective study determines sites of JCV persistence in immunologically healthy individuals.

Clinical Evidence of Disease Anticipation in Families Segregating a C9orf72 Repeat Expansion

Abstract Full Text
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JAMA Neurol. 2017;74(4):445-452. doi:10.1001/jamaneurol.2016.4847

This cohort study examines evidence for disease anticipation in families carrying a C9orf72 repeat expansion by analyzing age at onset, disease duration, and age at death in successive generations.

Association of Collateral Blood Vessels Detected by Arterial Spin Labeling Magnetic Resonance Imaging With Neurological Outcome After Ischemic Stroke

Abstract Full Text
free access
JAMA Neurol. 2017;74(4):453-458. doi:10.1001/jamaneurol.2016.4491

This cohort study assesses the association between the presence of collateral vessels identified using arterial spin labeling magnetic resonance imaging and neurologic outcome in patients after acute ischemic stroke.

Long-term Outcomes After Autologous Hematopoietic Stem Cell Transplantation for Multiple Sclerosis

Abstract Full Text
free access has audio
JAMA Neurol. 2017;74(4):459-469. doi:10.1001/jamaneurol.2016.5867

This multicenter cohort study of patients with multiple sclerosis treated with autologous hematopoietic stem cell transplantation (AHSCT) evaluates the long-term outcomes after AHSCT for the treatment of multiple sclerosis.

Clinical Implications of Basic Neuroscience Research

Electronic Dura Mater Meddling in the Central Nervous System

Abstract Full Text
JAMA Neurol. 2017;74(4):470-475. doi:10.1001/jamaneurol.2016.5767

This review of preclinical applications assesses the potential of the electronic dura mater to deliver electrical and chemical stimulation to targeted areas of the central nervous system for extended periods.

Clinical Pathologic Conference

A Woman in Her 40s With Headache and New-Onset Seizures

Abstract Full Text
JAMA Neurol. 2017;74(4):476-480. doi:10.1001/jamaneurol.2016.2961

This case report describes a woman in her 40s with a history of plasma cell leukemia who presented with 1 month of intermittent headaches followed by a seizure.

Images in Neurology

The Tadpole Pupil

Abstract Full Text
JAMA Neurol. 2017;74(4):481. doi:10.1001/jamaneurol.2016.5981

This case report describes the association between a tadpole pupil and Horner syndrome.

Comment & Response

Rituximab in Neuromyelitis Optica Spectrum Disorders: Why Not as First-Line Therapy

Abstract Full Text
JAMA Neurol. 2017;74(4):482. doi:10.1001/jamaneurol.2016.5933

Rituximab in Neuromyelitis Optica Spectrum Disorders—Reply: Why Not as First-Line Therapy

Abstract Full Text
JAMA Neurol. 2017;74(4):482-483. doi:10.1001/jamaneurol.2016.5936

Considering Blood Pressure Level in the Association Between Serum Calcium Level and the Size and Expansion in Patients With Intracerebral Hemorrhage—Reply

Abstract Full Text
JAMA Neurol. 2017;74(4):483-484. doi:10.1001/jamaneurol.2016.6011

Considering Blood Pressure Level in the Association Between Serum Calcium Level and the Size and Expansion in Patients With Intracerebral Hemorrhage

Abstract Full Text
JAMA Neurol. 2017;74(4):483. doi:10.1001/jamaneurol.2016.6045

Correct Data and Meta-analytic Approaches Show the Reduced Risk of Concussion for Athletes Playing at Higher Altitudes

Abstract Full Text
JAMA Neurol. 2017;74(4):484-485. doi:10.1001/jamaneurol.2016.6065

Correct Data and Meta-analytic Approaches Show the Reduced Risk of Concussion for Athletes Playing at Higher Altitudes—Reply

Abstract Full Text
JAMA Neurol. 2017;74(4):485-486. doi:10.1001/jamaneurol.2016.6068

Correct Data and Meta-analytic Approaches Show the Reduced Risk of Concussion for Athletes Playing at Higher Altitudes

Abstract Full Text
JAMA Neurol. 2017;74(4):485. doi:10.1001/jamaneurol.2016.6071

Not All Middle Cerebral Artery M2 Segments Are the Same

Abstract Full Text
JAMA Neurol. 2017;74(4):486-487. doi:10.1001/jamaneurol.2016.6168

Not All Middle Cerebral Artery M2 Segments Are the Same

Abstract Full Text
JAMA Neurol. 2017;74(4):487-488. doi:10.1001/jamaneurol.2016.6171

Response to Endovascular Therapy for Acute Ischemic Stroke With Occlusion of the Middle Cerebral Artery M2 Segment—Reply

Abstract Full Text
JAMA Neurol. 2017;74(4):488-489. doi:10.1001/jamaneurol.2016.6165
Peer Reviewers List

JAMA Neurology Peer Reviewers in 2016

Abstract Full Text
free access online only
JAMA Neurol. 2017;74(4):e164875. doi:10.1001/jamaneurol.2016.4875
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
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JAMA Neurol. 2017;74(4):380. doi:10.1001/jamaneurol.2016.3990
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