Felippe Borlot, MD, MSc; Brigid M. Regan, BSc (Hons); Anne S. Bassett, MD, FRCPC; et al.
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JAMA Neurol. 2017;74(11):1301-1311. doi:10.1001/jamaneurol.2017.1775
This cross-sectional study evaluates the prevalence of pathogenic copy number variations and identifies possible candidate copy number variations and genes in adults with epilepsy and intellectual disability with unknown cause.
Line K. Gjærde, MD; Michael Gamborg, PhD; Lars Ängquist, PhD; et al.
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JAMA Neurol. 2017;74(11):1312-1318. doi:10.1001/jamaneurol.2017.1627
This population-based cohort study of schoolchildren born from the 1930s through the 1980s in Denmark investigates whether childhood body mass index (BMI) and change in BMI are associated with adult ischemic stroke and assesses whether the associations are age dependent or influenced by birth weight.
Walter N. Kernan, MD; Catherine M. Viscoli, PhD; Jennifer L. Dearborn, MD; et al.
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JAMA Neurol. 2017;74(11):1319-1327. doi:10.1001/jamaneurol.2017.2136
This secondary analysis of the Insulin Resistance Intervention After Stroke trial estimates the relative and absolute effectiveness of pioglitazone after ischemic stroke or transient ischemic attack in subgroups of patients defined by pretreatment risk for stroke or myocardial infarction.
Xia Wang, PhD; Thompson G. Robinson, MD; Tsong-Hai Lee, MD; et al.
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JAMA Neurol. 2017;74(11):1328-1335. doi:10.1001/jamaneurol.2017.2286
This secondary analysis reports on the association of low-dose and standard-dose intravenous alteplase treatment with age, ethnicity (Asian vs non-Asian), and severity of acute ischemic stroke among patients in the ENCHANTED randomized clinical trial.
Bastien Joubert, MD; Catherine Chapelon-Abric, MD; Lucie Biard, MD, PhD; et al.
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JAMA Neurol. 2017;74(11):1336-1344. doi:10.1001/jamaneurol.2017.2492
This cohort study identifies prognostic factors for immunosuppressive treatment in patients with neurosarcoidosis and assesses the association of such treatment with relapse of the disease.
Carol A. Derby, PhD; Mindy J. Katz, MPH; Richard B. Lipton, MD; et al.
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JAMA Neurol. 2017;74(11):1345-1351. doi:10.1001/jamaneurol.2017.1964
This birth cohort study examined trends in dementia incidence and concomitant trends in cardiovascular comorbidities among individuals aged 70 years or older who were enrolled in the Einstein Aging Study between 1993 and 2015.
Jeffrey D. Long, PhD; James A. Mills, MA; Blair R. Leavitt, MD; et al.
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JAMA Neurol. 2017;74(11):1352-1360. doi:10.1001/jamaneurol.2017.2107
This study uses data from the Track and COHORT studies to examine an approach to planning prediagnosis clinical trials for Huntington disease.
Gregoire Boulouis, MD, MSc; Arne Lauer, MD; Ahmer Khawdja Siddiqui, MD; et al.
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JAMA Neurol. 2017;74(11):1361-1367. doi:10.1001/jamaneurol.2017.2149
This cohort study examines the clinical imaging factors associated with unfavorable imaging profile evolution for thrombectomy in patients with ischemic stroke initially transferred to non鈥搕hrombectomy-capable stroke centers.
Guido Ahle, MD; Valérie Touitou, MD, PhD; Nathalie Cassoux, MD, PhD; et al.
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JAMA Neurol. 2017;74(11):1368-1373. doi:10.1001/jamaneurol.2017.2545
This case series describes the clinical presentation of optic nerve infiltration, its imaging characteristics, and outcomes in patients with primary central nervous system lymphomas.